Bruck, R., Aeed, H., Shirin, H., Matas, Z., Azidel, L., Avni, Y. and Halpern, Z. (1999): The hydroxyl radical scavengers dimethylsulfoxide and dimethylthiourea protect rats against thioacetamide-induced fulminant
Authors:M. Batista, M. Ginani, D. Melo, and A. Oliveira
ZnS(1-x)MSx(x=0.01 and M=Mn2+, Cu2+ and Eu2+) compounds have been obtained by precipitation from homogeneous solutions of zinc, copper, manganese and europium salts,
with S2- as the precipitating anion, formed by the decomposition of thioacetamide. The thermal study of the milled zinc acetate, thioacetamide,
copper acetate, manganese acetate and europium nitrate, respectively, was studied for thermal analyis TG/DSC. XRD respect
exhibits a zinc blend crystal structure.
The volatilization losses of mercury before, during and after neutron irradiation were studied. To minimize the losses, respectively,
were added to the standards, thiourea, L-cysteine, thioacetamide and ammonium sulfide. It was possible to minimize the losses
by preserving the standard at −20°C after irradiation. No loss was seen in the biological materials after irradiation.
Arsenic, selenium and antimony were determined in four different tin samples. After distillation from HBr−H2SO4 medium arsenic and selenium were precipitated with thioacetamide, and antimony was subsequently separated by deposition on
iron powder. The separated samples were counted on a high-resolution Ge(Li) γ-spectrometer. The sensitivity of the method
is highly satisfactory.
The determination of 210Po in phosphoric acid reagent by alpha-ray spectrometry using extraction chromatographic resin is presented. The decontamination factors of interference elements were measured. It was observed that HCl, HNO3, ascorbic acid, thioacetamide and Cu were free from 210Po but Pb contain small amounts of 210Po. 210Po in phosphoric acid samples was ranged from <8 to 2.4 Bq/l. The detection limit of 210Po in 50 ml of phosphoric acid is 8 mBq/l with a counting time of 1 day undercounting efficiency of 30%.
Instrumental neutron activation analysis was applied to the determination of the elements Na, K, Br, As, Rb, Zn, Co, Fe and Sc in Brazilian rice samples and in biological standards. Hg and Se concentrations were determined by using a simple radiochemical separation. The chemical procedure was carried out by means of distillation of Hg and Se in HBr medium and subsequent precipitation of selenium by sodium metabisulfite and mercury by thioacetamide. The accuracy of the instrumental and radiochemical methods was evaluated by means of analysis of the Reference Materials NBS-Bovine Liver, Bowen's Kale and NBS-Rice Flour.
Authors:Erika Rapavi, Klára Szentmihályi, Erzsébet Fehér, Andrea Lugasi, Edit Székely, Tímea Kurucz, Zs. Pallai, and Anna Blázovics
In order to evaluate the effect of diosmin-hesperidin containing drug on redox balance and Cu, Zn, Fe and Mn concentrations of toxin-injured liver, Wistar albino rats were subjected to thioacetamide administration (500 mg TAA/l in their drinking water) with and without drug (425 mg/kg body weight/day). Animals were treated for 30 days. No significant change in the concentration of Zn, Cu, Mn and Fe in the liver was measured in TAA-treated animals compared to control. Diosmin-hesperidin mixture treatment increased levels of Fe and Zn and decreased concentration of Cu of the liver in TAA-treated animals. These alterations were not significant. Decrease of both the total scavenger capacity (TSC) and the activity of superoxide dismutase (SOD) in liver homogenates were observed in TAA-treated rats. The diosmin-hesperidin-supplemented diet also significantly decreased the TSC and activity of SOD in liver of both the control and toxin-treated animals. On the basis of results it seems that high dosage of the diosmin-hesperidin mixture induces slight changes in the Cu, Zn, Mn and Fe content of the liver, however it may decrease the scavenger capacity and the activity of SOD when applied either alone or together with thioacetamide.
Authors:Y. Shafiq, M. Al-Hissoni, M. Jassim, and M. Abdul Azzez
Kits were developed for labeling sulphur microcolloids with99mTc. The microcolloids were prepared to get the desired particle size. The stannous chloride was treated with sulphide ions released from thioacetamide in the presence of carboxymethyl cellulose and the pH of the reaction was adjusted to 3.0. The contents of single reaction vial were reacted with99mTc, the radiochemical yield was higher than 95%. Sulphur-microcolloid kits were stable and the stability was followed for 6 hours. The freeze-dried kits were followed more than three months after production and were found stable. Bone marrow uptake in rabbits was determined to be about 36%. The preparation of99mTc-sulphur microcolloid is performed in single step process and axellent node scintigraphy was obtained using experimental animal.
Galisteo, M., Suárez, A., Montilla, M. P., et al.: Protective effects of Rosmarinus tomentosus ethanol extract on thioacetamide-induced liver cirrhosis in rats. Phytomedicine, 2006, 13 , 101–108.
Montilla M. P