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Crawley, J. T., Zanardelli, S., Chion, C. K., et al.: The central role of thrombin in hemostasis. J. Thromb. Haemost., 2007, 5 (Suppl. 1), 95–101. Mosesson, M. W

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increased levels of prothrombin fragments demonstrate the prothrombotic state of these patients. Thrombin generation (TG) tests are global hemostasis assays applicable for the overall functional assessment of the hemostasis ( 10 ). TG measurement is

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Aoki, I., Aoki, N., Kawano, K., Shimoyama, K., Maki, A., Homori, M., Yanagishawa, A., Yamamoto, M., Kawai, Y. and Ishikawa, K. (1997): Platelet-dependent thrombin generation in patients with hyperlipidemia. JACC 30 , 91

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Acta Veterinaria Hungarica
Authors: Renata Rafaj, Vesna Matijatko, Ivana Kiš, Nada Kučer, Tatjana Živičnjak, Niksa Lemo, Zdravko Žvorc, Mirna Brkljačić and Vladimir Mrljak

Korte, W., Clarke, S. and Lefkowitz, J. B. (2000): Short activated partial thromboplastin times are related to increased thrombin generation and an increased risk for thromboembolism. Am. J. Clin. Pathol. 113 , 123

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Schelling, G., Block, T., Blanke, E. és mtsai: Application of a fibrinogen-thrombin-collagen-hased haemostatic agent in experimental injuries of liver and spleen. J. Trauma, 1998, 28 , 472–475. Blanke E

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-Westendorf J, Marten S, Michalski F. Outcome of NOAC exposure during pregnancy (...and the problem of event reporting...). Blood 2015; 126: 1125. 23 Weitz JI. Factor Xa and thrombin

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64 17 25 Stangier, J.: Clinical pharmacokinetics and pharmacodynamics of the oral direct thrombin inhibitor dabigatran etexilate. Clin

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. For measuring clopidogrel efficacy, ADP (0.2 mM, Roche) was used as agonist agent. Efficiency of tirofiban was determined indirectly, as the overall platelet function independent from ADP reactivity. Thrombin receptor-activating peptide (TRAP; 0.2 mM

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Orvosi Hetilap
Authors: Lajos Driesz, Éva Barabás, Ildikó Bodócs, Zoltán Szántó, György Herr, Gábor Bencsik, László Pál and József Borbola

novel, reversible, oral direct thrombin inhibitor: interpretation of coagulation assays and reversal of anticoagulant activity. Thromb. Haemost., 2012, 103 (6), 1116–1127. 11

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position on the biochemical markers of coagulation activation in healthy subjects: evidence of reduced thrombin generation. J. Thromb. Hemost., 2003, 1 , 380–381. Godio M. The

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