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Authors: Teodora Mocan, S. Clichici, L. Agoşton-Coldea, L. Mocan, Ş Şimon, I. Ilie, A. Biriş and Adriana Mureşan

25 Goodman CM, McCusker CD, Yilmaz T, Rotello VM: Toxicity of gold nanoparticles functionalized with cationic and anionic side chains. Bioconjugate Chem. 15, 897–900 (2004

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. Pharmacol. 2007 219 151 161 Kuroda, K. (1992) Mitotic toxicity, sister chromatid exchange, and

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Authors: Y. Zhang, W. Zheng, Q.C. Ying, L.-E. Shi, Z.-L. Zhang, M.-Z. Shi and Z.-X. Tang

. Toxicol. , 47 , 1231 – 1238 . GAO , Y. , SHEN , J. , YIN , J. , LI , C. , FU , C. , CHO , S. ( 2013 ): A subchronic dietary toxicity study

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): Agrochemical Year Book. Korean Agricultural Chemicals Industrial Association. Seoul, Republic of Korea. Aslan, I., Ozbek, H., Calmasur, O. and Sahln, F. (2004): Toxicity of essential oil vapours to two greenhouse pests

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and acaricidal effect of three Lamiaceae plant essential oils against Tetranychus urticae Koch and Bemisia tabaci Genn . Ind. Crop. Prod. 23 , 140 – 146 . Choi , W. I. , Lee , S. G. , Park , H. M. and Ahn , Y. J. ( 2004 ): Toxicity

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). Recent studies concluded that oxidative stress, exhibited by exposure to toxic chemicals, causes a major damage to sperm quality by disrupting the anti-oxidant and reactive oxygen species (ROS) balance and thus resulting in abnormalities of

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): Toxicity of heavy metals to microorganisms and microbial processes in agricultural soils: a review. Soil Biol. Biochem. , 30 , 1389–1414. McGrath S. P. Toxicity of heavy metals

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Abstract  

Microcalorimetry was applied to study the toxic action of two cobalt compounds such as bis(salicylideniminato-3-propyl)methylaminocobalt(II) (denoted as Co(II)) and Co(III) sepulchrate trichloride (denoted as Co(sep)3+) on (E. coli) DH5α. The power-time curves of the E. coli DH5α growth were determined, and the thermokinetics parameters such as the growth rate constant k, the maximum power output P m and the time (t m) corresponding to the P m were obtained. The half-inhibitory concentrations (IC50) of Co(II) and Co(sep)3+ to E. coli DH5α were 15 and 42.1 mg mL−1, respectively. The experimental results revealed that the toxicity of the Co(II) compound was larger than that of Co(sep)3+. On the other hand, the scanning electron microscopy (SEM) demonstrated that the two cobalt compounds had the same toxic mechanism on E. coli DH5α, which was attributed to the damage of cell wall of the bacteria caused by both Co(II) and Co(sep)3+. Furthermore, accumulation of intracellular cobalt of E. coli DH5α, due to the interaction of Co(II) or Co(sep)3+ and E. coli DH5α, has been found by using inductively coupled plasma (ICP) analytical technique.

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Authors: H. Sumano, Lilia Gutierrez, C. Velazquez and Sayuri Hayashida

Tran Ba Huy, P. and Deffrennes, D. (1988): Aminoglycoside toxicity - influence of dosage regimen on drug uptake and correlation between drug binding and some clinical features. Acta Oto-laryngol. 105, 511-515. Aminoglycoside

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Authors: Anna Sobeková, Katarína Holovská, Viera Lenártová, Slávka Flešárová and P. Javorský

Bus, J. S., Gibson, J. E. (1984) Paraquat: model for oxidant-initiated toxicity. Environ. Health Persp. 55 , 37–46. Gibson J. E. Paraquat: model for oxidant-initiated toxicity

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