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611 Dillioglugil MO, Maral Kir H, Gulkac MD, Ozon Kanli A, Ozdogan HK, Acar O, Dillioglugil O: Protective effects of increasing vitamin E and A doses on cisplatin-induced oxidative damage to

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. and Packer, L. (1995): Vitamin E: Beyond antioxidant function. Am. J. Clin. Nutr. 62 , 1501-1509. Vitamin E: Beyond antioxidant function Am. J. Clin. Nutr

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Buckley, D.J., Morrissey, P.A. & Gray, J.I. (1995): Influence of dietary vitamin E on the oxidative stability and quality of pig meat. J. Anim. Sci. , 73 , 3122–3130. Gray J

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The purpose of the present study was to investigate the effect of experimental T-2 toxin load (2.35 mg/kg of feed) and vitamin E supply in the drinking water (10.5 mg/bird/day) on vitamin E levels of the blood plasma and liver in broiler chickens in a 14-day experiment. It was found that T-2 toxin load did not influence vitamin E content of the blood plasma except at day 3 after the toxin load when a moderate increase was detected in plasma vitamin E. No significant changes were found in vitamin E content of the liver. The simultaneous use of high-dose vitamin E supplementation and T-2 toxin load caused a significantly higher plasma vitamin E content but the changes were less expressed in the group subjected to T-2 toxin load. Vitamin E supply also resulted in a marked and significant increase in vitamin E concentrations of the liver on days 3 and 7 even in the T-2 loaded group, but this concentration significantly decreased thereafter. The results show that T-2 contamination of the diet has an adverse effect on the utilisation of vitamin E in broiler chickens.

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53 33 39 Kökçam I, Nazıroğlu M: Effects of vitamin E supplementation on blood antioxidant levels in patients with Behçet’s disease. Clinical

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Journal of Thermal Analysis and Calorimetry
Authors: Alexandre G. S. Prado, André L. F. Santos, Carolina P. Pedroso, Thiago O. Carvalho, Lilian R. Braga, and Sheila M. Evangelista

vitamins are useful for prevention, being used as drugs or cosmetic products [ 2 ]. Vitamin A (also called retinol) has been shown to improve depigmentation of photodamaged skin [ 3 ]. Vitamin E contributes to the antioxidant defense of the skin, absorbing

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In our study, the protective effects of vitamin E and Se (selenium) against cigarette smoke hazards on second-hand smoker (passive smoker) male mice (Balb/c) were investigated. Serum MDA levels in the smoke-exposed mice were found higher than serum MDA levels of control mice and Se- and vitamin E-treated mice. But, the MDA levels of smoke-exposed plus Se- and vitamin E-treated mice were found lower than MDA levels of smoke-exposed mice at the end of the three and five months. According to these results, application of vitamin E and Se, when given to smoke-exposed mice together, had an additive protective effect against cigarette smoke hazards (p<0.05). Vitamin E also had protective effect on formation of 8-OHdG in smoke-exposed mice. The serum 8-OHdG amounts of smoke-exposed plus vitamin E-treated mice were found low, but the serum 8-OHdG amounts of smoke-exposed mice were found high. Also 8-OHdG levels in the serum of the smoke-exposed mice were increased which occurs as a result of DNA oxidation (p<0.05). At the end of the three and five months, COMT (catechol-o-methyl transferase) activity of smoke-exposed mice livers were increased but, vitamin E and/or Se showed a significant protective effect on changing of COMT activity only at the end of the 5 months. Our results showed that MDA levels and 8-OHdG amounts were increased in the serum of smoke-exposed mice. On the other hand, vitamin E and Se had an additive protective effect against increasing MDA level. Also vitamin E had a protective effect against formation of 8-OHdG amounts and COMT activity alterations.

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peroxidation, and impairment in anti-oxidant status induced by CCl 4 ( 3 , 13 , 35 ). Vitamin E (VE) is one of the most potent lipid-soluble free radical scavengers, believed to be one of the primary components of the anti-oxidant system of the spermatozoa

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Acta Veterinaria Hungarica
Authors: Tibor Gaál, L. Wágner, F. Husvéth, H. A. Manilla, P. Vajdovich, N. Balogh, I. Lóth, and Katalin Németh S.

. (ed.) Vitamin E, A comprehensive treatise. Marcel Dekker Inc., New York. pp. 372-389. Vitamin E, A comprehensive treatise. 372 389

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strains due to inappropriate antibiotic application and to maintain treatment of bacterial infections in the future [ 7, 14 ]. Vitamin E as a promising candidate molecule in the combat of infectious diseases Basic molecular features of vitamin E Vitamin E

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