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Browse our Medical Journals - AKJournals
Among all scientific traditions alive, medical publishing has a good chance to be the oldest. The first fully peer reviewed academic journal, “Medical Essays and Observations” was launched in 1731 by the Royal Society in Edinburgh. Since then, hundreds of medical journals have been published worldwide. Medical publication in Hungary started in 1857 when the famous physician, Markusovszky founded “Orvosi Hetilap”, which has been published since then every week (with short breaks during the world wars). It is now a most prestigious piece in AKJournals’ portfolio, listed in Journal Citation Reports, with a remarkable impact factor.
Discover the latest journals in Medical and Health Sciences
The primary function of medical articles is the validation of cutting-edge theoretical and clinical research, by providing reference and relevant forums. New drugs and medical practices can only enter the mainstream practise if their randomised trials had passed under the critical lens of prestigious peer reviewed journals. Technical reports help practitioners to improve their arsenal. Case reports confirm theories and provide tools for investigating or disclosing possible malpractice. Review articles serve educational purposes. Some more popular articles may play a role in educating the interested audience.
Types of medical articles
The papers published in medical journals can be classified in the following main categories
Research articles report about novel research results, of both theoretical and (direct or indirect) practical relevance.
Review articles survey specific topics by summarising and analysing all information available in the medical literature. Reviews are kind of combining results from different studies on the same topic. They can be useful for specialists in the field, may help them to prevent, diagnose, or treat a particular disease.
Case reports and case series reports about a concrete story of a concrete patient. They can be interesting because of their uniqueness, not matching any known diagnosis or describing unexpected symptoms. The report should describe each of the diagnosis, treatment, the patient’s response to it and the follow-up history. Case series are related reports about similarly treated patients.
Editorials are typically not peer reviewed shorter communications from senior members of the Editorial Board or from invited renown scholars. They discuss questions of relevance for the scientific community at the moment (say, about public health, or more generally, the health system).
Letters to the editor are articles of the interactive type, a form for readers to contact the medical journal. They can express comments, questions, or criticisms regarding some articles published in that journal. They provide a sophisticated forum for medical communities.
Medical Journals at AKJournals
AKJournals has 9 medical journals. Three of them are in Hungarian. The other six journals are in English and accept submissions from all over the world. Some of them are widely available Open Access journals. The covered topics include immunology, medical imaging, physiology, and veterinary and health care science. In these journals, you can find more than 11.000 medical articles altogether. A filter tool helps to single out the relevant titles. In addition to that, we highly recommend using the search box to find the most important topics only
Time perception is a cognitive process involving both the ability to estimate the duration of an event (time estimation, TE) and the subjective perception of its passage (time passage, TP). Studies show that alteration in TE/TP is associated with substance use disorders. However, little is known about the impact of these alterations in potentially problematic online behaviors. We explore TE and TP while participants were exposed to cues related to videogames, pornography, and TV series, and the relationship of TE and TP with scores from instruments that measure problematic gaming (PG), problematic pornography use (PPU), and problematic binge-watching (BW).
Participants from three independent samples (40 men from Luxembourg; 99 Spanish men, 111 Spanish women) completed an experimental task designed to assess TE and TP while they were exposed to short clips related to videogames, pornography, TV series, and documentaries (control condition). Participants also completed different self-reports.
Whereas men underestimated the time that they were exposed to pornography and TV series, women overestimated it. For videogames, we showed a consistent pattern of overestimation of time duration. Time was systematically perceived as passing faster while participants were presented with TV series and pornography. Regarding the association between time perception and PG, PPU, and BW, TE did not correlate with any of the indicators of problematic engagement assessed; but TP correlated with several of these indicators.
Discussion and conclusions
The present preliminary results showed mixed evidence regarding the involvement of time perception in gaming, pornography use, and binge-watching.
Klebsiella pneumoniae is a major human pathogen as it is responsible for various infections. In the past years hypervirulent K. pneumoniae (hvKP) emerged and disseminated worldwide. In this review a summary will be given about epidemiology, detection and antibiotic resistance of hypervirulent K. pneumoniae. A common feature of hypervirulent K. pneumoniae is a combined expression of several virulence factors. A mucoviscosus phenotype, certain capsulare serotypes (e.g.: K1, K2, K28, K47, K63) together with additional genetic markers namely, magA, rmpA or iucABCD, are needed in combinations to achieve the hypervirulent pathotype. Plasmid coded virulence determinants are also detected, that indicates horizontal gene transfer of hypervirulence factors in K. pneumoniae.
Interestingly, infections caused by hypervirulent K. pneumoniae occur usually in the community in otherwise healthy people, and during these infections multiple infection sites are detected. Clinical pictures include both invasive infections and local abscess formation. Pyogenic liver abscess is the most frequently reported clinical manifestation and abscess formation in brain, spleen and lung are also diagnosed. Additionally, meningitis, endophthalmitis, trombophlebitis, pneumonia can also develop.
In the early reports, hypervirulent K. pneumoniae strains exhibited enhanced virulence but these were susceptible to commonly used antibiotics. However, recently KPC, VIM, NDM and OXA-48 carbapenemase producing hypervirulent K. pneumoniae strains are increasingly reported, furthermore, well-known high-risk K. pneumoniae clones (e.g.: ST11, ST147, ST307) can develop hypervirulent pathotype, that poses an even more alarming challenge.
The intertemporal and risk decision-making impairments are vital cognitive mechanisms in internet use disorder (IUD). However, the underlying neural mechanisms for these two decision-making dysfunctions in individuals with IUD remain unclear.
This study employed Functional Near-Infrared Spectroscopy (fNIRS) to record changes in blood oxygen concentration in the prefrontal cortex of individuals with IUD during intertemporal and risk decision-making tasks.
The findings revealed that the intertemporal decision-making deficits in IUD group were primarily associated with reduced activation in the left dorsolateral prefrontal cortex (dlPFC) and orbitofrontal cortex (OFC) and FC from the left dlPFC to the right dlPFC. On the other hand, risk decision-making impairments were linked to decreased OFC activation and weakened functional connectivity from the left dlPFC to the right dlPFC and OFC.
Discussions and Conslusions
These results suggested that while there were common neural mechanisms underlying intertemporal and risk decision-making impairments in individuals with IUD, specific neural foundations existed for each type of dysfunction.
Gaming disorder (GD) screening often involves self-report survey measures to detect the presence of symptoms. Studies have shown that gamers' responses vary greatly across survey items. Some symptoms, such as preoccupation and tolerance, are frequently reported by highly engaged but non-problematic gamers, and therefore these symptoms are thought to lack specificity and are suggested to be less important in classification decisions. We argue that the influence of response categories (e.g., dichotomous responses, such as ‘yes’ or ‘no’; or frequency categories, such as ‘rarely’ and ‘often’) on item responses has been relatively underexplored despite potentially contributing significantly to the psychometric performance of items and scales. In short, the type of item response may be just as important to symptom reporting as the content of survey questions. We propose some practical alternatives to currently used item categories across GD tools. Research should examine the performance of different response categories, including whether certain response categories aid respondents' comprehension and insight, and better capture pathological behaviours and harms.
Introduction: Beta-lactams are among the most commonly used
antibiotics. Their efficacy is time-dependent, thus the European Society of
Clinical Microbiology and Infectious Diseases (ESCMID) recommends that their
plasma concentrations should remain above the minimal inhibitory concentration
(MIC) of the pathogenic bacteria throughout the dosing period (100%fT>MIC).
However, according to several studies, it appears that the plasma concentrations
of beta-lactam antibiotics can be suboptimal in critically ill patients.
Objective: The aim of our study was to determine the
pharmacodynamic target achievement of beta-lactam antibiotics (meropenem,
piperacillin/tazobactam, and ceftriaxone) among critically ill adult patients
admitted to an intensive care unit. Method: We conducted a
prospective, observational single-centre study in a teaching hospital.
Critically ill patients who were prescribed meropenem, piperacillin or
ceftriaxone were enrolled. Trough antibiotic plasma concentration was measured
using high-performance liquid chromatography (HPLC) and liquid
chromatography–tandem mass spectrometry (LC–MS/MS) to assess the achievement of
the pharmacodynamic target of 100%fT>MIC. The target concentration was
determined based on the definitions of the European Committee on Antimicrobial
Susceptibility Testing (EUCAST), depending on the pathogen. The primary endpoint
was the proportion of patients not achieving therapeutic plasma concentrations.
Results: A total of 60 antibiotic level measurements were
performed in 28 patients. The median age of the patients was 64.5 ± 28,7 years,
80% (n = 22 patients) were male. The reason for admission was medical in 35.7%
(n = 10), surgical/trauma in 53.5% (n = 15) and burns in 10.7% (n = 3) of
patients. The therapeutic target was not achieved in 39.3% (n = 11) of patients,
66.6% (n = 6) in the meropenem group, 41.6% (n = 5) in the piperacillin group
and 12.5% (n = 1) in the ceftriaxone group. Discussion: A
significant proportion of critically ill patients receiving beta-lactam
antibiotics did not achieve their target concentration, particularly
piperacillin and meropenem. Conclusion: Our pilot study
confirms the importance of therapeutic drug monitoring in critically ill
patients receiving beta-lactam therapy. Orv Hetil. 2023; 164(48): 1904–1911.
One of the most common dentoalveolar surgical procedures, with the most
difficulties and complications, is the surgical removal of wisdom teeth. The
topic is very topical, both because of its frequency and its diversity. It is
diverse because its diagnostic evaluation in relation to the root canal
mandibulae requires great expertise, the surgical technique is not standardised
in the majority of the cases and the surgeon is often forced to improvise. The
complications, the treatment of which is part of our daily tasks, are relatively
frequent and sometimes require a strong institutional background. The literature
on the subject is vast and the guidelines proposed often change from year to
year. The authors review the indications, contraindications, diagnostics,
surgical management, complications associated with the surgical removal of the
wisdom teeth and their management. The authors present an overview of the
protocols of the different international schools and formulate current
recommendations for general practitioners, dentists and dentoalveolar surgeons
in Hungary. Orv Hetil. 2023; 164(48): 1887–1894.
Schistosomiasis, a worm infection known as bilharziasis or blood fluke, typically
occurs in tropical regions. In temperate climates like Hungary, only imported
cases are reported. The disease can affect the skin, gastrointestinal tract, or
bladder, depending on the subtype of the worm. We present the case of a
32-year-old male of African origin who visited the urology clinic with
macroscopic hematuria. Despite initial antibiotic therapy, the hematuria
persisted. A cystoscopy revealed polyp-like lesions in the bladder, which were
resected. Histological examination excluded bladder cancer and described a
granulomatous and eosinophil granulocyte-rich inflammation. On top of that, the
presence of Schistosoma haematobium eggs and sexually mature
parasites in the venules was confirmed. After that, antihelmintic therapy was
administered, leading to the resolution of symptoms. Notably, this case is the
first documented instance of bladder schistosomiasis diagnosed in Hungary. Our
paper aims to raise awareness of this rare condition while providing insights
into its development, treatment, and potential complications. Orv Hetil. 2023;
Introduction: The association of chronic diseases with eating
disorders requires increased attention due to the potential for serious
complications and increased risk of mortality. Eating disorders and sub-clinical
eating disorders are associated with maladaptive emotion regulation, which may
be both triggers and maintaining factors of the disease. To our knowledge, the
role of cognitive emotion regulation in eating disorders in adolescents with
inflammatory bowel disease and type 1 diabetes mellitus has not been
investigated to date. Objective: We analysed the relationship
between cognitive emotion regulation and symptoms of eating disorder in
adolescents aged 14 to 18 years, focusing on young people with type 1 diabetes
mellitus and inflammatory bowel disease. Our research aimed to identify the role
of specific cognitive emotion regulation strategies in eating disorders in
patient populations with chronic disease. Method: In our study,
300 adolescents completed the Cognitive Emotion Regulation Questionnaire and the
Self Administrated Psychiatric Scales for Children and Adolescents after
informed consent. The four study groups consisted of 157 physically healthy
adolescents, 51 adolescents diagnosed with IBD, 61 adolescents diagnosed with
type 1 diabetes mellitus and 31 adolescents diagnosed with anorexia nervosa.
Results: The results of our study showed that rumination
and positive reframing were significantly associated with symptoms of eating
disorders in adolescents with inflammatory bowel disease, and self-blame and
rumination were significantly associated with symptoms of eating disorders in
adolescents with type 1 diabetes mellitus diagnosis, through an indirect
pathway. Discussion: Our results suggest that cognitive emotion
regulation strategies are indirectly related to symptoms of eating disorders
among adolescents with the chronic illness studied. More frequent use of
negative emotion regulation strategies of self-blame and rumination increases
the incidence of eating disorder symptoms, and less frequent use is associated
with fewer eating disorder symptoms. Greater use of positive reappraisal is
associated with fewer eating disorder symptoms. Conclusion: We
recommend the incorporation of cognitive emotion regulation strategies in the
complex care of chronically ill adolescents, both in screening and in
interventions. Orv Hetil. 2023; 164(48): 1895–1903.
Introduction: Knowledge and prejudices of medical students
regarding marginalised patient groups can influence their interactions with
patients. Objective: The perceptions of medical students from
the point of view of which social groups they would be less likely to accept as
patients. Method: Medical students of the University of Szeged
completed a voluntary, anonymous questionnaire (n = 410) in 2021, which included
several groups of questions (sociodemographic characteristics, family
background, career choice motivations, shaping of medical identity, future
professional plans, working during university; warmth and competence, social
distance, own experiences among 19 social groups). Results:
Students were least likely to meet abusers, vaccine deniers and prisoners in
their future work. Female medical students were more reluctant to meet abusers,
while their male counterparts homeless, alcoholic, AIDS and psychiatric
patients, and senior students the vaccine denial group and AIDS patients. Their
experiences with different social groups also varied widely. Most of them
personally knew Romani people, drug users, psychiatric patients and alcoholics.
In clinical practice, they encountered Romani people, alcoholics and psychiatric
patients the most. During their education, they heard most often about vaccine
deniers, alcoholics, Romani people, homeless people, AIDS patients.
Discussion: Overall, the students were accepting patients
from different social groups. However, their personal and educational
experiences behind their prejudices were very diverse.
Conclusion: It would be important to strive to meet and get
to know different social groups during university studies in behavioural
sciences and public health as well as during clinical work, so that students can
learn to communicate with them appropriately. Orv Hetil. 2023; 164(48):
This analysis of current and historical research and clinical reports observes that the relationship between psychedelics and schizophrenia is complex and there are reports of psychedelics benefiting this population. Specifically, lower doses of psychedelics (mostly LSD) appear to have a potential beneficial impact on the negative symptoms of schizophrenia.