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  • 1 Department of Pathology, Section of Clinical Diagnosis, Faculty of Veterinary Medicine and Animal Science, National Autonomous University of Mexico 04510 Mexico City, Mexico
  • | 2 Department of Animal Production: Poultry, Faculty of Veterinary Medicine and Animal Science, National Autonomous University of Mexico 04510 Mexico City, Mexico
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In the present study, specific-pathogen-free, 2-week-old Leghorn chickens were experimentally infected with strain 73688 of infectious bursal disease virus (IBDV) in order to evaluate haematological and histological changes that might suggest a pathomechanism for haemorrhages in this disease. At 96 hours post infection (hpi) a significant increase in prothrombin time was detected in the absence of visible lesions in myeloid bone marrow tissue and of significant thrombocytopenia. The aforementioned findings suggest alteration of the secondary coagulation mechanisms and not a direct effect of virus on thrombocytes or its precursors.

  • Ley, D. H., Yamamoto, K. and Bickford, A. A. (1983): The pathogenesis of infectious bursal disease: serologic, histopathologic, and clinical chemical observations. Avian Dis. 27, 1060-1085.

    'The pathogenesis of infectious bursal disease: serologic, histopathologic, and clinical chemical observations ' () 27 Avian Dis. : 1060 -1085.

    • Search Google Scholar
  • Okoye, J. O. A. (1984): Infectious bursal disease of chickens. Vet. Bull. 54, 425-436.

    'Infectious bursal disease of chickens ' () 54 Vet. Bull. : 425 -436.

  • Banda, C. A. (1996): Obtaining, serotyping, and virulence characterisation of three field isolates of infectious bursal disease (IBDV) in Mexico (in Spanish). Facultad de Medicina Veterinaria y Zootecnia, UNAM, Mexico City.

    Obtaining, serotyping, and virulence characterisation of three field isolates of infectious bursal disease (IBDV) in Mexico (in Spanish) , ().

    • Search Google Scholar
  • CalderóAn, A. N. (1998): Pathogenesis of thrombocytopenia in acute classical swine fever. Acta Vet. Brno 67, 115-119.

    'Pathogenesis of thrombocytopenia in acute classical swine fever ' () 67 Acta Vet. Brno : 115 -119..

    • Search Google Scholar
  • Campbell, W. T. (1992): Avian Hematology and Cytology. First edition. Iowa State University Press, Ames, USA.

    Avian Hematology and Cytology , ().

  • Banda, C. A., Valladares-de la Cruz, J. C. and Navarro-Hernandez, J. A. (1999): Clinical and pathological characterisation of three isolates of infectious bursal disease virus obtained from commercial broiler flocks in Mexico (in Spanish) Veterinaria MéAxico (Mexico City) 30, 7-18.

    'Clinical and pathological characterisation of three isolates of infectious bursal disease virus obtained from commercial broiler flocks in Mexico (in Spanish) ' () 30 Veterinaria MéAxico (Mexico City) : 7 -18.

    • Search Google Scholar
  • Sharma, J. M., Dohms, J. E. and Metz, A. L. (1989): Comparative pathogenesis of serotype 1 and variant serotype 1 isolates of infectious bursal disease virus and their effect on humoral and cellular immune competence of specific-pathogen-free chickens. Avian Dis. 33, 112-124.

    'Comparative pathogenesis of serotype 1 and variant serotype 1 isolates of infectious bursal disease virus and their effect on humoral and cellular immune competence of specific-pathogen-free chickens ' () 33 Avian Dis. : 112 -124.

    • Search Google Scholar
  • Skeeles, J. K., Slavick, M., Beasley, J. N., Brown, A. H. and Meinecke, C. F. (1980): An agerelated coagulation disorder associated with experimental infection with infectious bursal disease virus. Am. J. Vet. Res. 41, 1458-1461.

    'An agerelated coagulation disorder associated with experimental infection with infectious bursal disease virus ' () 41 Am. J. Vet. Res. : 1458 -1461.

    • Search Google Scholar
  • Van den Berg, T. P. (2000): Acute infectious bursal disease in poultry: a review. Avian Pathol. 29, 175-179.

    'Acute infectious bursal disease in poultry: a review ' () 29 Avian Pathol. : 175 -179..

  • Tsukamoto, K., Tanimura, N., Mase, M. and Imai, K. (1995): Comparison of virus replication efficiency in lymphoid tissues among three infectious bursal disease virus strains. Avian Dis. 39, 844-852.

    'Comparison of virus replication efficiency in lymphoid tissues among three infectious bursal disease virus strains ' () 39 Avian Dis. : 844 -852.

    • Search Google Scholar
  • Villegas, P. (2001): Avian Virus Diseases. Laboratory Manual AVMD 8050. College of Veterinary Medicine, University of Georgia, Georgia, USA. p. 62.

    Avian Virus Diseases , () 62.

  • Inoue, M., Fujita, A. and Maeda, K. (1999): Lysis of myelocytes in chickens infected with infectious bursal disease virus. Vet. Pathol. 36, 146-151.

    'Lysis of myelocytes in chickens infected with infectious bursal disease virus ' () 36 Vet. Pathol. : 146 -151.

    • Search Google Scholar
  • Lasher, H. N. and Shane, S. M. (1994): Infectious bursal disease. World's Poultry Sci. J. 50, 133-166.

    'Infectious bursal disease ' () 50 World's Poultry Sci. J. : 133 -166..

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