Acta Veterinaria Hungarica
Volume/Issue:
Volume 55: Issue 4
Serological evidence for Babesia canis infection of horses and an endemic focus of B. caballi in Hungary
Authors: S. Hornok 1 , Renate Edelhofer 2 , G. Földvári 1 , Anja Joachim 2 , and R. Farkas 1
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  • 1 Szent István University Department of Parasitology and Zoology, Faculty of Veterinary Science H-1078 Budapest István u. 2 Hungary
  • | 2 University of Veterinary Medicine Department of Pathobiology, Institute of Parasitology and Zoology Vienna Austria
Pages:
491–500
Online Publication Date:
10 Nov 2007
Publication Date:
01 Dec 2007
Article Category:
Research Article
DOI:
https://doi.org/10.1556/avet.55.2007.4.8
Keywords:
Horse babesiosis; Babesia canis ; Babesia caballi ; seroprevalence; Hungary
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In order to evaluate the seroconversion of horses to Babesia caballi and B. canis in Hungary, blood samples were collected from 371 animals on 23 different locations of the country. The presence of antibodies to B. caballi was screened with a competitive ELISA. All 29 positive samples came from one region (the Hortobágy). The prevalence of infection did not show correlation with sexes, and reached 100% in the age group of 2–5 years. Babesia canis -specific antibodies were demonstrated by IFAT in 6.74% of animals kept in 7 regions. The titres were low or medium level (1:40 to 1:160), indicating that the horses had previously been exposed to this piroplasm, but their infection must have been limited. The highest seropositivity rate was observed in the age group of 3–4 years, and males (stallions and geldings) were significantly more frequently infected than females. However, neither B. caballi nor B. canis could be identified in the peripheral blood samples of infected horses by PCR. Since most of the B. caballi -positive horses remained negative in the B. canis IFAT, whereas seroconversion solely to B. canis was detected in several regions of the country, serological cross-reaction between the two species can be discounted. This is the first serological evidence of horses being naturally infected with B. canis , supporting the view that piroplasms are less host specific than previously thought.

  • Allen, P. C., Frerichs, W. M. and Holbrook, A. A. (1975 a ): Experimental acute Babesia caballi infections I. Red blood cell dynamics. Exp. Parasitol. 37 , 67–77.

    Holbrook A. A. , 'Experimental acute Babesia caballi infections I. Red blood cell dynamics ' (1975 ) 37 Exp. Parasitol. : 67 -77.

    • Search Google Scholar

  • Allen, P. C., Frerichs, W. M. and Holbrook, A. A. (1975 b ): Experimental acute Babesia caballi infections II. Response of platelets and fibrinogen. Exp. Parasitol. 37 , 373–379.

    Holbrook A. A. , 'Experimental acute Babesia caballi infections II. Response of platelets and fibrinogen ' (1975 ) 37 Exp. Parasitol. : 373 -379.

    • Search Google Scholar

  • Babos, S. (1965): Kullancsok — Ixodidea (in Hungarian). Fauna Hungariae 18 , 28–31.

    Babos S. , 'Kullancsok — Ixodidea (in Hungarian) ' (1965 ) 18 Fauna Hungariae : 28 -31.

  • Baneth, G., Kenny, M. J., Tasker, S., Anug, Y., Shkap, V., Levy, A. and Shaw, S. E. (2004): Infection with a proposed new subspecies of Babesia canis, Babesia canis subsp. presentii , in domestic cats. J. Clin. Microbiol. 42 , 99–105.

    Shaw S. E. , 'Infection with a proposed new subspecies of Babesia canis, Babesia canis subsp. presentii, in domestic cats ' (2004 ) 42 J. Clin. Microbiol. : 99 -105.

    • Search Google Scholar

  • Bashiruddin, J. B., Camma, C. and Rebelo, E. (1999): Molecular detection of Babesia equi and Babesia caballi in horse blood by PCR amplification of part of the 16S RNA gene. Vet. Parasitol. 84 , 75–83.

    Rebelo E. , 'Molecular detection of Babesia equi and Babesia caballi in horse blood by PCR amplification of part of the 16S RNA gene ' (1999 ) 84 Vet. Parasitol. : 75 -83.

    • Search Google Scholar

  • Butler, C. M., van Gils, J. A. M. and van der Kolk, J. H. (2005): Acute infection with Babesia caballi in a Dutch Standardbred foal after visiting a stud in Normandy (France) (in Dutch). Tijdsch. Diergeneesk. 130 , 726–731.

    Kolk J. H. , 'Acute infection with Babesia caballi in a Dutch Standardbred foal after visiting a stud in Normandy (France) (in Dutch) ' (2005 ) 130 Tijdsch. Diergeneesk. : 726 -731.

    • Search Google Scholar

  • Buza, L., Hajdu, G. and Temesi, Z. (1953): Occurrence of horse babesiosis in Hungary (in Hungarian). Magyar Állatorvosok Lapja 8 , 265–268.

    Temesi Z. , 'Occurrence of horse babesiosis in Hungary (in Hungarian) ' (1953 ) 8 Magyar Állatorvosok Lapja : 265 -268.

    • Search Google Scholar

  • Buza, L., Hajdu, G. and Temesi, Z. (1955): New cases of horse babesiosis in Hungary (in Hungarian). Magyar Állatorvosok Lapja 10 , 427–429.

    Temesi Z. , 'New cases of horse babesiosis in Hungary (in Hungarian) ' (1955 ) 10 Magyar Állatorvosok Lapja : 427 -429.

    • Search Google Scholar

  • Camacho, A. T., Guitian, F. J., Pallas, E., Gestal, J. J., Olmeda, A. S., Habela, M. A., Telford, S. R. 3rd and Spielman, A. (2005): Theileria (Babesia) equi and Babesia caballi infections in horses in Galicia, Spain. Trop. Anim. Health Prod. 37 , 293–302.

    Spielman A. , 'Theileria (Babesia) equi and Babesia caballi infections in horses in Galicia, Spain ' (2005 ) 37 Trop. Anim. Health Prod. : 293 -302.

    • Search Google Scholar

  • Criado-Fornelio, A., Martinez-Marcos, A., Buling-Sarana, A. and Barba-Carretero, J. C. (2003): Molecular studies on Babesia, Theileria and Hepatozoon in Southern Europe: Part I. Epizootiological aspects. Vet. Parasitol. 113 , 189–201.

    Barba-Carretero J. C. , 'Molecular studies on Babesia, Theileria and Hepatozoon in Southern Europe: Part I. Epizootiological aspects ' (2003 ) 113 Vet. Parasitol. : 189 -201.

    • Search Google Scholar

  • Criado, A., Martinez, J., Buling, A., Barba, J. C., Merino, S., Jefferies, R. and Irwin, P. J. (2006): New data on epizootiology and genetics of piroplasms based on sequences of small ribosomal subunit and cytochrome b genes. Vet. Parasitol. 142 , 238–247.

    Irwin P. J. , 'New data on epizootiology and genetics of piroplasms based on sequences of small ribosomal subunit and cytochrome b genes ' (2006 ) 142 Vet. Parasitol. : 238 -247.

    • Search Google Scholar

  • de Waal, D. T. (1992): Equine piroplasmosis: a review. Br. Vet. J. 148 , 6–14.

    Waal D. T. , 'Equine piroplasmosis: a review ' (1992 ) 148 Br. Vet. J. : 6 -14.

  • Földvári, G., Hell, É. and Farkas, R. (2005): Babesia canis canis in dogs from Hungary: detection by PCR and sequencing. Vet. Parasitol. 127 , 221–226.

    Farkas R. , 'Babesia canis canis in dogs from Hungary: detection by PCR and sequencing ' (2005 ) 127 Vet. Parasitol. : 221 -226.

    • Search Google Scholar

  • Frerichs, W. M., Holbrook, A. A. and Johnson, A. J. (1969): Equine piroplasmosis: complement-fixation titres of horses infected with Babesia caballi . Am. J. Vet. Res. 30 , 697–702.

    Johnson A. J. , 'Equine piroplasmosis: complement-fixation titres of horses infected with Babesia caballi ' (1969 ) 30 Am. J. Vet. Res. : 697 -702.

    • Search Google Scholar

  • Friedhoff, K. T. and Soule, C. (1996): An account on equine babesiosis. Rev. Sci. Tech. 15 , 1191–1201.

    Soule C. , 'An account on equine babesiosis ' (1996 ) 15 Rev. Sci. Tech. : 1191 -1201.

  • Friedhoff, K. T., Tenter, A. M. and Muller, I. (1990): Haemoparasites of equines: impact on international trade of horses. Rev. Sci. Tech. 9 , 1187–1194.

    Muller I. , 'Haemoparasites of equines: impact on international trade of horses ' (1990 ) 9 Rev. Sci. Tech. : 1187 -1194.

    • Search Google Scholar

  • Holman, P. J., Frerichs, W. M., Chieves, L. and Wagner, G. G. (1993): Culture confirmation of the carrier status of Babesia caballi -infected horses. J. Clin. Microbiol. 31 , 698–701.

    Wagner G. G. , 'Culture confirmation of the carrier status of Babesia caballi-infected horses ' (1993 ) 31 J. Clin. Microbiol. : 698 -701.

    • Search Google Scholar

  • Hornok, S., Edelhofer, R. and Farkas, R. (2006): Seroprevalence of canine babesiosis in Hungary suggesting breed predisposition. Parasitol. Res. 99 , 638–642.

    Farkas R. , 'Seroprevalence of canine babesiosis in Hungary suggesting breed predisposition ' (2006 ) 99 Parasitol. Res. : 638 -642.

    • Search Google Scholar

  • International Collating Centre (1997): Disease outbreaks. Equine Disease Quarterly 6 , 1. http://www.ca.uky.edu/gluck/q/1997/oct97/Q_oct97.htm

    'Disease outbreaks ' (1997 ) 6 Equine Disease Quarterly : 1 -.

  • Joyner, L. P., Donnelly, J. and Huck, R. A. (1981): Complement fixation tests for equine piroplasmosis ( Babesia equi and B. caballi ) performed in the UK during 1976 to 1979. Equine Vet. J. 13 , 103–106.

    Huck R. A. , 'Complement fixation tests for equine piroplasmosis (Babesia equi and B. caballi) performed in the UK during 1976 to 1979 ' (1981 ) 13 Equine Vet. J. : 103 -106.

    • Search Google Scholar

  • Kappmeyer, L. S., Perryman, L. E., Hines, S. A., Baszler, T. V., Katz, J. B., Hennager, S. G. and Knowles, D. P. (1999): Detection of equine antibodies to Babesia caballi by recombinant B. caballi rhoptry-associated protein 1 in a competitive-inhibition enzyme-linked immunosorbent assay. J. Clin. Microbiol. 37 , 2285–2290.

    Knowles D. P. , 'Detection of equine antibodies to Babesia caballi by recombinant B. caballi rhoptry-associated protein 1 in a competitive-inhibition enzyme-linked immunosorbent assay ' (1999 ) 37 J. Clin. Microbiol. : 2285 -2290.

    • Search Google Scholar

  • Leblond, A., Pradier, S., Pitel, P. H., Fortier, G., Boireau, P., Chadoeuf, J. and Sabatier, P. (2005): An epidemiological survey of equine anaplasmosis ( Anaplasma phagocytophilum ) in Southern France (in French). Rev. Sci. Tech. 24 , 899–908.

    Sabatier P. , 'An epidemiological survey of equine anaplasmosis (Anaplasma phagocytophilum) in Southern France (in French) ' (2005 ) 24 Rev. Sci. Tech. : 899 -908.

    • Search Google Scholar

  • Mancianti, F., Nardoni, S., Cecconi, M. and Bonanno, E. L. (2000): Prevalence of antibabesia antibodies in racehorses in Tuscany. Ippologia 11 , 29–33.

    Bonanno E. L. , 'Prevalence of antibabesia antibodies in racehorses in Tuscany ' (2000 ) 11 Ippologia : 29 -33.

    • Search Google Scholar

  • Mantran, A., Votion, D. M. and Amory, H. (2004): Piroplasmose: une réalité belge? (in Flemish). Studiedag van de Belgian Equine Practitioners Society 21 . http://www.ivis.org/proceedings/BEPS/2004/Amory/IVIS.pdf

  • Mehlhorn, H. and Schein, E. (1998): Redescription of Babesia equi Laveran, 1901 as Theileria equi Mehlhorn, Schein 1998. Parasitol. Res. 84 , 467–475.

    Schein E. , 'Redescription of Babesia equi Laveran, 1901 as Theileria equi Mehlhorn, Schein 1998 ' (1998 ) 84 Parasitol. Res. : 467 -475.

    • Search Google Scholar

  • Pavlovic, I., Milutinovic, M., Petkovic, D., Terzin, D. and Terzin, V. (2002): Epizootiological research of canine babesiosis in the Belgrade district. J. Protozool. Res. 12 , 10–15.

    Terzin V. , 'Epizootiological research of canine babesiosis in the Belgrade district ' (2002 ) 12 J. Protozool. Res. : 10 -15.

    • Search Google Scholar

  • Price, J. S., Jackson, B., Eastell, R., Goodship, A. E., Blumsohn, A., Wright, I., Stoneham, S., Lanyon, L. E. and Russell, R. G. (1995): Age-related changes in biochemical markers of bone metabolism in horses. Equine Vet. J. 27 , 201–207.

    Russell R. G. , 'Age-related changes in biochemical markers of bone metabolism in horses ' (1995 ) 27 Equine Vet. J. : 201 -207.

    • Search Google Scholar

  • Savini, G., Battistini, M. L., Scaramozzino, P., Tittarelli, M. and Molteni, C. (1997): Equine babesiosis: the situation in Italy (in Italian). Summa 14 , 35–40.

    Molteni C. , 'Equine babesiosis: the situation in Italy (in Italian) ' (1997 ) 14 Summa : 35 -40.

    • Search Google Scholar

  • Sréter, T., Széll, Z. and Varga, I. (2005): Spatial distribution of Dermacentor reticulatus and Ixodes ricinus in Hungary: evidence for change? Vet. Parasitol. 128 , 347–351.

    Varga I. , 'Spatial distribution of Dermacentor reticulatus and Ixodes ricinus in Hungary: evidence for change? ' (2005 ) 128 Vet. Parasitol. : 347 -351.

    • Search Google Scholar

  • Zahler, M. and Gothe, R. (2000): Infections of horses with Babesia caballi and Theileria equi in Germany — an epidemiological analysis (in German). Tierärztl. Umschau 55 , 655–657.

    Gothe R. , 'Infections of horses with Babesia caballi and Theileria equi in Germany — an epidemiological analysis (in German) ' (2000 ) 55 Tierärztl. Umschau : 655 -657.

    • Search Google Scholar

  • Zahler, M., Schein, E., Rinder, H. and Gothe, R. (1998): Characteristic genotypes discriminate between Babesia canis isolates of differing vector capacity and pathogenicity to dogs. Parasitol. Res. 84 , 544–548.

    Gothe R. , 'Characteristic genotypes discriminate between Babesia canis isolates of differing vector capacity and pathogenicity to dogs ' (1998 ) 84 Parasitol. Res. : 544 -548.

    • Search Google Scholar
Cover Acta Veterinaria Hungarica
Acta Veterinaria Hungarica
Print ISSN:
0236-6290
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  • Béla DÉNES (National Food Chain Safety Office, Budapest Hungary)
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  • Tibor NÉMETH (University of Veterinary Medicine, Budapest, Hungary)
  • Zsuzsanna NEOGRÁDY (University of Veterinary Medicine, Budapest, Hungary)
  • Alessandra PELAGALLI (University of Naples Federico II, Naples, Italy)
  • Kurt PFISTER (Ludwig-Maximilians-University of Munich, Munich, Germany)
  • László SOLTI (University of Veterinary Medicine, Budapest, Hungary)
  • József SZABÓ (University of Veterinary Medicine, Budapest, Hungary)
  • Péter VAJDOVICH (University of Veterinary Medicine, Budapest, Hungary)
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Acta Veterinaria Hungarica
Language English
Size A4
Year of
Foundation		 1951
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per Year		 1
Issues
per Year		 4
Founder Magyar Tudományos Akadémia
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