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  • 1 Nutrition and Meat Science, H-2053 Herceghalom, Gesztenyés u.1, Hungary
  • 2 University of Kaposvár, Kaposvár, Hungary
  • 3 Association of Hungarian Simmental Cattle Breeders, Bonyhád, Hungary
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The objective of this study was to estimate the effect of single-nucleotide polymorphisms (SNPs) on the breeding value of fertility (BVF) and the breeding value of beef (BVB) in Hungarian Simmental cattle. Genotypes were determined on a high-density Illumina Bovine DNA Chip. Data screening and data identification were performed by multi-locus mixed-model. Statistical analyses were carried out to find associations between individual genotypes and the investigated quality values. Three loci showed considerable association with BVF (–log10 P = 9.5, 9.9 and 14.5, respectively) on chromosomes 9, 28 and 29, respectively. The frequencies of their minor alleles (MAF) were 0.375, 0.355 and 0.354, respectively. Two loci showed association with BVB (–log10 P = 25.3 and 22.7) on chromosomes 2 and 11, respectively (their MAF were 0.438 and 0.229). The abovementioned loci provide a straightforward possibility to assist selection by molecular tools.

  • Abo-Ismail, M. K., Voort, G. V., Squires, J. J., Swanson, K. C., Mandell, I. B., Liao, X., Stothard, P., Moore, S., Plastow, G. and Miller, S. P. (2014): Single nucleotide polymorphisms for feed efficiency and performance in crossbred beef cattle. BMC Genet. 15, 14.

    • Search Google Scholar
    • Export Citation
  • Adoligbe, C., Zan, L., Farougou, S., Wang, H. and Ujjan, J. A. (2012): Bovine GDF10 gene polymorphism analysis and its association with body measurement traits in Chinese indigenous cattle. Mol. Biol. Rep. 39, 40674075.

    • Search Google Scholar
    • Export Citation
  • Allais, S., Levéziel, H., Hocquette, J. F., Rousset, S., Denoyelle, C., Journaux, L. and Renand, G. (2014): Fine mapping of quantitative trait loci underlying sensory meat quality traits in three French beef cattle breeds. J. Anim. Sci. 92, 43294341.

    • Search Google Scholar
    • Export Citation
  • Anton, I., Kovács, K., Fésüs, L., Várhegyi, J., Lehel, L., Hajda, Z., Polgár, J. P., Szabó, F. and Zsolnai, A. (2008): Effect of DGAT1 and TG gene polymorphism on intramuscular fat and milk production traits in different cattle breeds in Hungary. Acta Vet. Hung. 56, 181186.

    • Search Google Scholar
    • Export Citation
  • Anton, I., Zsolnai, A., Holló, I., Repa, I. and Holló, G. (2013): Effect of thyroglobulin gene polymorphism on the intramuscular fat content in cattle examined by x-ray computed tomography and Soxhlet methods. Arch. Tierzucht 59, 593596.

    • Search Google Scholar
    • Export Citation
  • Armitage, P. (1955): Tests for linear trends in proportions and frequencies. Biometrics 11, 375386.

  • Ashburner, M., Ball, C. A., Blake, J. A., Botstein, D., Butler, H., Cherry, J. M., Davis, A. P., Dolinski, K., Dwight, S. S., Eppig, J. T., Harris, M. A., Hill, D. P., Issel-Tarver, L., Kasarskis, A., Lewis, S., Matese, J. C., Richardson, J. E., Ringwald, M., Rubin, G. M. and Sherlock, G. (2000): Gene ontology: tool for the unification of biology. Nat. Genet. 25, 2529.

    • Search Google Scholar
    • Export Citation
  • Ekerljung, M., Li, X., Lundén, A., Lundström, K., Marklund, S. and Näsholm, A. (2012): Associations between candidate SNPs in the calpain 1, calpastatin and leptin genes and meat tenderness among Swedish beef populations. Acta Agric. Scand., Section A – Anim. Sci. 62, 114119.

    • Search Google Scholar
    • Export Citation
  • Fagerberg, L., Hallström, B. M., Oksvold, P., Kampf, C., Djureinovic, D., Odeberg, J., Habuka, M., Tahmasebpoor, S., Danielsson, A., Edlund, K., Asplund, A., Sjöstedt, E., Lundberg, E., Szigyarto, C. A., Skogs, M., Takanen, J. O., Berling, H., Tegel, H., Mulder, J., Nilsson, P., Schwenk, J. M., Lindskog, C., Danielsson, F., Mardinoglu, A., Sivertsson, A., von Feilitzen, K., Forsberg, M., Zwahlen, M., Olsson, I., Navani, S., Huss, M., Nielsen, J., Ponten, F. and Uhlén, M. (2013): Analysis of the human tissue-specific expression by genome-wide integration of transcriptomics and antibody-based proteomics. Mol. Cell Proteomics 13, 397406.

    • Search Google Scholar
    • Export Citation
  • Fortes, M. R. S., Reverter, A., Hawken, R. J., Bolormaa, S. and Lehnert, S. A. (2012): Candidate genes associated with testicular development, sperm quality, and hormone levels of inhibin, luteinizing hormone, and insulin-like growth factor 1 in Brahman bulls. Biol. Reprod. 87, 58.

    • Search Google Scholar
    • Export Citation
  • Fortes, M. R. S., Reverter, A., Kelly, M., McCulloch, R. and Lehnert, S. A. (2013): Genome-wide association study for inhibin, luteinizing hormone, insulin-like growth factor 1, testicular size and semen traits in bovine species. Andrology 1, 644650.

    • Search Google Scholar
    • Export Citation
  • Füller, I. (2010): Further development of selection for meat production improvement in the Hungarian Fleckvieh cattle. PhD Thesis. http://phd.ke.hu/fajlok/1275040173-doktori_final.pdf.

  • Gill, J. L., Bishop, S. C., McCorquodale, C., Williams, J. L. and Wiener, P. (2009): Association of selected SNP with carcass and taste panel assessed meat quality traits in a commercial population of Aberdeen Angus-sired beef cattle. Genet. Sel. Evol. 41, 36.

    • Search Google Scholar
    • Export Citation
  • Goravanahally, M. P., Sen, A., Inskeep, E. K. and Flores, J. A. (2007): PKC epsilon and an increase in intracellular calcium concentration are necessary for PGF2 alpha to inhibit LHstimulated progesterone secretion in cultured bovine steroidogenic luteal cells. Reprod. Biol. Endocrinol. 5, 37.

    • Search Google Scholar
    • Export Citation
  • Han, Y. and Peñagaricano, F. (2016): Unravelling the genomic architecture of bull fertility in Holstein cattle. BMC Genet. 17, 143.

  • Húth, B., Holló, I., Füller, I., Polgár, J. P. and Komlósi, I. (2013): Association of Hungarian Simmental Breeders – 25 years serving breeding of Hungarian Simmental [in Hungarian, with English abstract]. Állattenyésztés és Takarmányozás 62, 384397.

    • Search Google Scholar
    • Export Citation
  • Kadri, N. K., Sahana, G., Charlier, C., Iso-Touru, T., Guldbrandtsen, B., Karim, L., Nielsen, U. S., Panitz, F., Aamand, G. M., Schulman, N., Georges, M., Vilkki, J., Lund, M. S. and Druet, T. (2014): A 660-kb deletion with antagonistic effects on fertility and milk production segregates at high frequency in Nordic Red cattle: additional evidence for the common occurrence of balancing selection in livestock. PLOS Genet. 10, e1004049.

    • Search Google Scholar
    • Export Citation
  • Kim, J. Y., Burghardt, R. C., Wu, G., Johnson, G. A., Spencer, T. E. and Bazer, F. W. (2011): Select nutrients in the ovine uterine lumen. VIII. Arginine stimulates proliferation of ovine trophectoderm cells through MTOR-RPS6K-RPS6 signaling cascade and synthesis of nitric oxide and polyamines. Biol Reprod. 84, 7078.

    • Search Google Scholar
    • Export Citation
  • Kiss, A. M., Jády, B. E., Bertrand, E. and Kiss, T. (2004): Human box H/ACA pseudouridylation guide RNA machinery. Mol. Cell. Biol. 24, 57975807.

    • Search Google Scholar
    • Export Citation
  • Komlósi, I. and Húth, B. (2010): The evaluation of heifer and cow fertility in the Hungarian Fleckvieh cattle breed [in Hungarian, with English abstract]. Állattenyésztés és Takarmányozás 59, 423440.

    • Search Google Scholar
    • Export Citation
  • Krammer, J., Digel, M., Ehehalt, F., Stremmel, W., Füllekrug, J. and Ehehalt, R. (2011): Overexpression of CD36 and acyl-CoA synthetases FATP2, FATP4 and ACSL1 increases fatty acid uptake in human hepatoma cells. Int. J. Med. Sci. 8, 599614.

    • Search Google Scholar
    • Export Citation
  • Li, G., Penagaricano, F., Weigel, K. A., Zhang, Y., Rosa, G. and Khatib, H. (2012): Comparative genomics between fly, mouse, and cattle identifies genes associated with sire conception rate. J. Dairy Sci. 95, 61226129.

    • Search Google Scholar
    • Export Citation
  • Li, X., Ekerljung, M., Lundström, K. and Lundén, A. (2013): Association of polymorphisms at DGAT1, leptin, SCD1, CAPN1 and CAST genes with color, marbling and water holding capacity in meat from beef cattle populations in Sweden. Meat Sci. 94, 153158.

    • Search Google Scholar
    • Export Citation
  • Liu, X., Usman, T., Wang, Y., Wang, Z., Xu, X., Wu, M., Zhang, Y., Zhang, X., Li, Q., Liu, L., Shi, W., Qin, C., Geng, F., Wang, C., Tan, R., Huang, X., Liu, A., Wu, H., Tan, S. and Yu, Y. (2015): Polymorphisms in epigenetic and meat quality related genes in fourteen cattle breeds and association with beef quality and carcass traits. Asian-Australas. J. Anim. Sci. 28, 467475.

    • Search Google Scholar
    • Export Citation
  • Minozzi, G., Nicolazzi, E. L., Stella, A., Biffani, S., Negrini, R., Lazzari, B., Ajmone-Marsan, P. and Williams, J. L. (2013): Genome wide analysis of fertility and production traits in Italian Holstein cattle. PLOS One 8, e80219.

    • Search Google Scholar
    • Export Citation
  • Nayeri, S., Sargolzaei, M., Abo-Ismail, M. K., May, N., Miller, P. S., Schenkel, F., Moore, S. S. and Stothard, P. (2016): Genome-wide association for milk production and female fertility traits in Canadian dairy Holstein cattle. BMC Genet. 17, 75.

    • Search Google Scholar
    • Export Citation
  • Pfarrer, C. D., Heeb, C. and Leiser, R. (2006): Expression of gap junctional connexins 26, 32 and 43 in bovine placentomes during pregnancy. Placenta 27, 7986.

    • Search Google Scholar
    • Export Citation
  • Picard, B., Jurie, C., Duris, M. P. and Renand, G. (2006): Consequences of selection for higher growth rate on muscle fibre development in cattle. Livestock Sci. 102, 107120.

    • Search Google Scholar
    • Export Citation
  • Segura, V., Vihjálmsson, B. J., Platt, A., Korte, A., Seren, Ü., Long, Q. and Nordborg, M. (2012): An efficient multi-locus mixed model approach for genome-wide association studies in structured populations. Nature Genet. 44, 825830.

    • Search Google Scholar
    • Export Citation
  • Tizioto, P. C., Meirelles, S. L., Veneroni, G. B., Tullio, R. R., Rosa, A. N., Alencar, M. M., Medeiros, S. R., Siqueira, F., Feijó, G. L., Silva, L. O., Torres, R. A. Jr. and Regitano, L. C. (2012): A SNP in ASAP1 gene is associated with meat quality and production traits in Nelore breed. Meat Sci. 92, 855857.

    • Search Google Scholar
    • Export Citation

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