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  • 1 Széchenyi István Egyetem, Mosonmagyaróvár
  • 1 Széchenyi István University
  • 2 Nemzeti Népegészségügyi Központ, Budapest
  • 2 National Public Health Center, Budapest
Open access

Összefoglalás

Egy vegyület akkor tekinthető ösztrogén hatásúnak, ha alacsony affinitással is, de az ösztrogén receptorokhoz (ER) kötődni képes, az ösztrogén érzékeny sejtekben, szövetekben biológiai hatást képes kiváltani, melyek hasonlóak a petefészek eredetű ösztrogén hormonok által előidézett folyamatokhoz.

Irodalmi adatok alapján a hígtrágyával történő öntözés és intenzív állattartásból származó trágya termőföldre juttatása következtében a szteroid ösztrogének, beleértve az ösztron E1, ösztradiol E2, ösztriol E3, valamint a szintetikus ösztrogén EE2, mindenütt jelen vannak a termőtalajban. A növények felhalmozhatják az ösztrogéneket gyökereikben és hajtásaikban, bekerülve a táplálékláncba akár hatást fejthetnek ki a humán egészségre. A vegyületek ösztrogén potenciálját legtöbbször a 17β-ösztradiol referencia vegyülethez viszonyított relatív potenciálként fejezik ki. Meghatározó szerepe van a vegyületek minőségének, ugyanis az egyes ösztrogénhatású vegyületek különböző hatással lehetnek a receptorokra

Ahogy korábban említettük, hígtrágya csak talajtani szakvéleményre alapozott talajvédelmi hatósági engedély birtokában juttatható ki mezőgazdasági területre, melyben az is meghatározásra kerül, hogy a területre milyen mennyiségű hígtrágya helyezhető el. A különböző típusú hígtrágyák nemcsak tápanyag összetételben, hanem EDC tartalomban is különböznek egymástól. A természetes hormon kiválasztódás és a hormonhatású készítmények felhasználása tekintetében fontos az állatállomány ivararányát és korcsoportját figyelembe venni. A jövőre nézve fontos, hogy toxikológiai vizsgálatokat végezzünk, és nagyobb hangsúlyt fektessünk a mezőgazdasági melléktermékek által kijuttatott hormonhatású anyagok mennyiségére és lehetséges hatásaira.

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