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  • 1 Department of Psychology, The Pennsylvania State University University Park, PA 16802, USA
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Nausea is an unpleasant sensation usually referred to the stomach and sometimes followed by vomiting. Little is known about the subjective aspects of nausea because like pain and fatigue, it is a private sensation. We conceive of nausea as a complex control mechanism that signals us when not to eat. Our research in the areas of motion sickness and chemotherapy has led us to propose that we each have a dynamic threshold for nausea, which depends on the interaction of inherent factors and more changeable psychological factors, and that this threshold effects the individual's cognitive appraisal of both the nauseogenic stimulus and his/her bodily change in response to the nauseogenic stimulus. Inherent factors that are described are age, gender and race; psychological factors that are included are anxiety, expectation, anticipation and adaptation. The physiological responses that have been found to accompany nausea include an increase in sympathetic nervous system activity, a decrease in parasympathetic activity, an increase of abnormal dysrhythmic gastric activity, and an increase in plasma vasopressin. It is concluded that beneficial selective reduction of nausea will depend on a greater knowledge of the interaction of the psychological and physiological variables.

  • Stern, R. M., Hu, S., LeBlanc, R., Koch, K. L. (1993) Chinese hyper-susceptibility to vection-induced motion sickness. Aviation, Space and Environmental Medicine 64, 827-830.

    'Chinese hyper-susceptibility to vection-induced motion sickness ' () 64 Aviation, Space and Environmental Medicine : 827 -830.

    • Search Google Scholar
  • Stern, R. M., Hu, S., Uijtdehaage, S. H. J., Muth, E. R., Xu, L. H., Koch, K. L. (1996) Asian hyper-susceptibility to motion sickness. Human Heredity 46, 7-14.

    'Asian hyper-susceptibility to motion sickness ' () 46 Human Heredity : 7 -14.

  • Stern, R. M., Hu, S., Vasey, M. W., Koch, K. L. (1989) Adaptation to vection-induced symptoms of motion sickness. Aviation, Space, and Environmental Medicine 60, 566-571.

    'Adaptation to vection-induced symptoms of motion sickness ' () 60 Aviation, Space, and Environmental Medicine : 566 -571.

    • Search Google Scholar
  • Jokerst, M. D., Gatto, M., Fazio, R., Gianaros, P. J., Stern, R. M., Koch, K. L. (1999) Effects of gender of subjects and experimenter on susceptibility to motion sickness. Aviation, Space and Environmental Medicine 70, 962-965.

    'Effects of gender of subjects and experimenter on susceptibility to motion sickness ' () 70 Aviation, Space and Environmental Medicine : 962 -965.

    • Search Google Scholar
  • Kelly, K. (1993) A neural control of gastric electrical and motor activity. In: Brooks, F. P., Evers, P. W. (eds) Nerves and the Gut. Slack, Thorofare, New Jersey.

  • Kirsch, I. (1999) How Expectancies Shape Experience. American Psychological Association, Washington, D.C. pp. 5-8.

    5 8

  • Koch, K. L., Stern, R. M., Vasey, M. W., Seaton, J. F., Demers, L. M., Harrison, T. S. (1990) Neuroendocrine and gastric myoelectric responses to illusory self-motion in men. Am. J. Physiol. 258, E304-E310.

    'Neuroendocrine and gastric myoelectric responses to illusory self-motion in men ' () 258 Am. J. Physiol. : E304 -E310.

    • Search Google Scholar
  • Levine, M. E., Stern, R. M. (2002) The effect of placebo-induced expectations on gastric tachyarrhythmia and vection-induced nausea. Neurogastroenterology and Motility. 14, 319.

    'The effect of placebo-induced expectations on gastric tachyarrhythmia and vection-induced nausea ' () 14 Neurogastroenterology and Motility : 319.

    • Search Google Scholar
  • Marten, P. A., Brown, T. A., Barlow, D. H., Borkovec, T. D., Shear, K. M., Lydiard, R. B. (1993) Evaluation of the ratings comprising the associated symptom criterion of DSM-III-R Generalized Anxiety Disorder. J. Nervous & Mental Disorders 181, 676-682.

    () 181 J. Nervous & Mental Disorders : 676 -682.

  • Morrow, G. R. (1989) Chemotherapy-related nausea and vomiting: Etiology and management. Cancer 39, 89-104.

    'Chemotherapy-related nausea and vomiting: Etiology and management ' () 39 Cancer : 89 -104.

    • Search Google Scholar
  • Reason, J. T., Brand, J. J. (1975) Motion Sickness. Academic Press, London.

  • Robertson, G. L. (1977) The regulation of vasopressin function in health and disease. Recent Progr. Hormonal Res. 33, 333-385.

    'The regulation of vasopressin function in health and disease ' () 33 Recent Progr. Hormonal Res. : 333 -385.

    • Search Google Scholar
  • Stern, R. M., Koch, K. L., Muth, E. R. (2000) Gastrointestinal System. In: Cacioppo, J. T., Tassinary, L. G., Berntson, G. G. (eds) Handbook of Psychophysiology, 2nd ed. Cambridge University Press, Cambridge, pp.

  • Stern, R. M., Koch, K. L. (1996) Motion sickness and differential susceptibility. Curr. Directions Psycholog. Sci. 5, 115-120.

    'Motion sickness and differential susceptibility ' () 5 Curr. Directions Psycholog. Sci. : 115 -120.

    • Search Google Scholar
  • Andrykowski, M. A. (1990) The role of anxiety in the development of anticipatory nausea in cancer chemotherapy: A review and synthesis. Psychosom. Med. 52, 458-475.

    'The role of anxiety in the development of anticipatory nausea in cancer chemotherapy: A review and synthesis ' () 52 Psychosom. Med. : 458 -475.

    • Search Google Scholar
  • Feldman, M., Samson, W. K., O'Dorisio, T. M. (1988) Apomorphine-induced nausea in humans: Release of vasopressin and pancreatic polypeptide. Gastroenterology 95, 721-726.

    'Apomorphine-induced nausea in humans: Release of vasopressin and pancreatic polypeptide ' () 95 Gastroenterology : 721 -726.

    • Search Google Scholar
  • Gianaros, P. J., Stern, R. M., Morrow, C. R., Hickok, J. T. (2001) Relationship of gastric myoelectrical and cardiac parasympathetic activity to chemotherapy-induced nausea. J. Psychosom. Res. 50, 263-266.

    'Relationship of gastric myoelectrical and cardiac parasympathetic activity to chemotherapy-induced nausea ' () 50 J. Psychosom. Res. : 263 -266.

    • Search Google Scholar
  • Edwards, C., Carmichael, J., Baylis, P., Harris, A. (1989) Arginine vasopressin - a mediator of chemotherapy induced emesis? Brit. J. Cancer 59, 467.

    'Arginine vasopressin - a mediator of chemotherapy induced emesis ' () 59 Brit. J. Cancer : 467.

    • Search Google Scholar
  • Eversmann, T., Gottsmann, M., Uhlich, E., Ulbrecht, G., von Werder, K., Scriba, P. C. (1978) Increased secretion of growth hormone, prolactin, antidiuretic hormone, and cortisol induced by the stress of motion sickness. Aviation, Space and Environmental Medicine 49, 53-57.

    'Increased secretion of growth hormone, prolactin, antidiuretic hormone, and cortisol induced by the stress of motion sickness ' () 49 Aviation, Space and Environmental Medicine : 53 -57.

    • Search Google Scholar
  • Gianaros, P. J., Quigley, K. S., Mordkoff, J. T., Stern, R. M. (2001) Gastricmyoelectrical and autonomic cardiac reactivity to laboratory stressors. Psychophysiology 38, 1-11.

    'Gastricmyoelectrical and autonomic cardiac reactivity to laboratory stressors ' () 38 Psychophysiology : 1 -11.

    • Search Google Scholar
  • Grant, P. J., Hughes, J. R., Dean, H. G., Davies, J. A., Prentice, C. R. M. (1986) Vasopressin and catecholamine secretion during apomorphine-induced nausea mediate acute changes in hemostatic function in man. Clin. Sci. 71, 621-624.

    'Vasopressin and catecholamine secretion during apomorphine-induced nausea mediate acute changes in hemostatic function in man ' () 71 Clin. Sci. : 621 -624.

    • Search Google Scholar
  • Hawthorn, J., Andrews, P. L. R., Ang, V. T. Y., Jenkins, J. S. (1988) Differential release of vasopressin and oxytocin in response to abdominal vagal afferent stimulation of apomorphine in the ferret. Brain Res. 438, 193-198.

    'Differential release of vasopressin and oxytocin in response to abdominal vagal afferent stimulation of apomorphine in the ferret ' () 438 Brain Res. : 193 -198.

    • Search Google Scholar
  • Jacobsen, P. B., Andrykowski, M. A., Redd, W. H., Die-Trill, M., Hakes, T. B., Kaufman, R. J., Currie, V. E., Holland, J. C. (1988) Nonpharmacologic factors in the development of post treatment nausea with adjuvant chemotherapy for breast cancer. Cancer 61, 379-385.

    'Nonpharmacologic factors in the development of post treatment nausea with adjuvant chemotherapy for breast cancer ' () 61 Cancer : 379 -385.

    • Search Google Scholar
  • Verbalis, J. G., Richardson, D. W., Stricker, E. M. (1987) Vasopressin release in response to nausea-producing agents and cholecystokinin in monkeys. Am. J. Physiol. 252, 749-753.

    'Vasopressin release in response to nausea-producing agents and cholecystokinin in monkeys ' () 252 Am. J. Physiol. : 749 -753.

    • Search Google Scholar
  • Xu, L. H., Koch, K. L., Summy-Long, J., Stern, R. M., Seaton, J. F., Harrison, T. S., Demers, L. M., Bingaman, S. (1993) Hypothalamic and gastric myoelectric responses during vection-induced nausea in healthy Chinese subjects. Am. J. Physiol. 265, E578-E584.

    'Hypothalamic and gastric myoelectric responses during vection-induced nausea in healthy Chinese subjects ' () 265 Am. J. Physiol. : E578 -E584.

    • Search Google Scholar

Editorial Board

    1. Csányi, Vilmos (Göd)
    1. Dudits, Dénes (Szeged)
    1. Falus, András (Budapest)
    1. Fischer, Ernő (Pécs)
    1. Gábriel, Róbert (Pécs)
    1. Gulya, Károly (Szeged)
    1. Gulyás, Balázs (Stockholm)
    1. Hajós, Ferenc (Budapest)
    1. Hámori, József (Budapest)
    1. Heszky, László (Gödöllő)
    1. Hideg, Éva (Szeged)
    1. E. Ito (Sanuki)
    1. Janda, Tibor (Martonvásár)
    1. Kavanaugh, Michael P. (Missoula)
    1. Kása, Péter (Szeged)
    1. Klein, Éva (Stockholm)
    1. Kovács, János (Budapest)
    1. Brigitte Mauch-Mani (Neuchâtel)
    1. Nässel, Dick R. (Stockholm)
    1. Nemcsók, János (Szeged)
    1. Péczely, Péter (Gödöllő)
    1. Roberts, D. F. (Newcastle-upon-Tyne)
    1. Sakharov, Dimitri A. (Moscow)
    1. Singh, Meharvan (Fort Worth)
    1. Sipiczky, Mátyás (Debrecen)
    1. Szeberényi, József (Pécs)
    1. Székely, György (Debrecen)
    1. Tari, Irma (Szeged)
    1. Vágvölgyi, Csaba (Szeged),
    1. L. Zaborszky (Newark)

 

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Acta Biologica Hungarica
Language English
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Year of
Foundation
1950
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Programme
changed title
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Founder Magyar Tudományos Akadémia
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H-1051 Budapest, Hungary, Széchenyi István tér 9.
Publisher Akadémiai Kiadó
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Chief Executive Officer, Akadémiai Kiadó
ISSN 0236-5383 (Print)
ISSN 1588-256X (Online)