View More View Less
  • 1 University of Uyo Department of Microbiology P.M.B. 1017 Uyo Nigeria
  • | 2 University of Uyo Department of Physics P.M.B. 1017 Uyo Nigeria
  • | 3 University of Uyo Department of Biochemistry P.M.B. 1017 Uyo Nigeria
  • | 4 University of Uyo Department of Obstetrics and Gynaecology P.M.B. 1017 Uyo Nigeria
Restricted access

Purchase article

USD  $25.00

1 year subscription (Individual Only)

USD  $784.00

Mycological research was conducted on the mycelial growth, keratinolytic proteinase activity and thermotolerance of dermatophytes associated with alopecia patients in Uyo, Nigeria. The results revealed that Microsporum sp. — AP 1 , Epidermophyton sp. — AP 2 , Trichophyton rubrum — AP 4 , Trichophyton mentagrophytes — AP 5 and a yeast Candida albicans — AP 3 isolated exhibited variable growth and keratinase activity at different temperatures. Microsporum sp. — AP 1 and T. mentagrophytes — AP 5 survived heat treatment at 90 °C but exhibited best mycelial growth at 30 °C (with 53.41 mg/50 ml biomass dry weight) and 40 °C (with 61.32 mg/50 ml biomass dry weight) respectively, after incubation for 2 weeks. Trichophyton rubrum — AP 4 and Epidermophyton sp. — AP 2 could not survive heat treatment at 90 °C but grew better at 40 °C (with 38.52 mg/50 ml biomass dry weight) and 30 °C (with 48.32 mg/50 ml biomass dry weight) respectively, over the same incubation period, while C. albicans — AP 3 grew better at 30 °C with 38.7 mg/50 ml biomass dry weight after 2 weeks, but failed to survive at 70 °C. All the isolates except Candida albicans — AP 3 survived at 80 °C and exhibited great potential to elaborate keratinolytic enzymes, with T. mentagrophytes demonstrating the best potential at 30 °C and 40 °C. Higher temperatures tended to reduce keratinolytic activities and there were significant (P <0.05) relationships between biomass weight and enzyme productivities of all the isolates except T. mentagrophytes . This indicates that in some dermatophytes keratinolytic proteinase activity is not a function of cell multiplicity. This plus the high thermostability of the enzymes are important attributes in the consideration of preventive and therapeutic methods against dermatophytes in the tropics.

  • Hay, R. J.: Dermatophytosis and other superficial mycoses. In: Mandell, Douglas and Pennett’s Principles and Practice of Infectious Diseases. 5th Edition. Churchill Livingstone 2000, pp. 2757–2768.

  • Nichoils, D. S. H., Midgley, G.: Onychomycosis caused by Trichophyton equinum . Clin Exp Dermatol 14 , 464–465 (1989).

    Midgley G. , 'Onychomycosis caused by Trichophyton equinum ' (1989 ) 14 Clin Exp Dermatol : 464 -465.

    • Search Google Scholar
  • Abdel-Hafez, S. I. I., El-said, A. A. M., Maghraby, T. A: Studies on fungi of students in Qena and Red Sea Governorates. Egypt Bull Fac Sci Assiat Univ 24 , 182–209 (1995).

    Maghraby T. A. , 'Studies on fungi of students in Qena and Red Sea Governorates ' (1995 ) 24 Egypt Bull Fac Sci Assiat Univ : 182 -209.

    • Search Google Scholar
  • El-Said, A. H. M.: Mycological and physiological studies on fungi isolated from skin diseases. Pakistan J Biol Sci 4 (11), 1432–1436 (2001).

    El-Said A. H. M. , 'Mycological and physiological studies on fungi isolated from skin diseases ' (2001 ) 4 Pakistan J Biol Sci : 1432 -1436.

    • Search Google Scholar
  • Takami, H. T., Horikoshi, K.: Production of extremely thermostable alkaline protease from Bacillus sp No. AH-101. Appl Microbiol Biotech 30 , 120–124 (1989).

    Horikoshi K. , 'Production of extremely thermostable alkaline protease from Bacillus sp No. AH-101 ' (1989 ) 30 Appl Microbiol Biotech : 120 -124.

    • Search Google Scholar
  • Manachini, P. L., Fortina, M. G., Parini, C.: Thermostable alkaline protease produced by Bacillus thermoruber: A new species of Bacillus. Appl Microbiol 25 , 409–413 (1989).

    Parini C. , 'Thermostable alkaline protease produced by Bacillus thermoruber: A new species of Bacillus ' (1989 ) 25 Appl Microbiol : 409 -413.

    • Search Google Scholar
  • Takuichi, I., Higuchi, D., Sei, Y., Koga, M.: Isolation of an extracellular proteinase, keratinase from Microsporum canis . Sabouraudia 20 , 281–288 (1982).

    Koga M. , 'Isolation of an extracellular proteinase, keratinase from Microsporum canis ' (1982 ) 20 Sabouraudia : 281 -288.

    • Search Google Scholar
  • Jain, P. C., Agrawal, S. C.: A note on the keratin decomposing capability of some fungi. Trans Mycol Soc Japan 21 , 513–517 (1980).

    Agrawal S. C. , 'A note on the keratin decomposing capability of some fungi ' (1980 ) 21 Trans Mycol Soc Japan : 513 -517.

    • Search Google Scholar
  • Dozie, I. N. S., Okeke, C. N., Unaeze, N. C.: A thermostable, alkaline-active, keratinolytic proteinase from Chrysosporium keratinophilum . World J Microbiol Biotech 10 , 563–567 (1994).

    Unaeze N. C. , 'A thermostable, alkaline-active, keratinolytic proteinase from Chrysosporium keratinophilum ' (1994 ) 10 World J Microbiol Biotech : 563 -567.

    • Search Google Scholar
  • Yu, R. J., Harmon, S. R., Blank, F.: Isolation and purification of an extracellular keratinase of Trichophyton mentagrophytes . J Bacteriol 96 , 1435–1436 (1968).

    Blank F. , 'Isolation and purification of an extracellular keratinase of Trichophyton mentagrophytes ' (1968 ) 96 J Bacteriol : 1435 -1436.

    • Search Google Scholar
  • William, C. D., Tonic, P. C., Stratrian, C., Leeman, U., Harmon, S.: Isolation and properties of extracellular protease of Trichophyton granulosum . Biochem et Biophys Act 167 , 597–599 (1978).

    Harmon S. , 'Isolation and properties of extracellular protease of Trichophyton granulosum ' (1978 ) 167 Biochem et Biophys Act : 597 -599.

    • Search Google Scholar
  • Sutton, D. A., Fothergill, A. W., Rinaldi, M. G.: Guide to Clinically Significant Fungi. 1 st Edition. Williams and Wilkins, Baltimore, 1998.

    Rinaldi M. G. , '', in Guide to Clinically Significant Fungi , (1998 ) -.

  • NCCLS: References method for broth dilution antifungal susceptibility testing of conidium-forming filametous fungi. Proposed Standard. National Committee for Clinical Laboratory Standard (NCCLS) Document, Wayne Pa, 1998, 38 p.

  • Rhode, B., Hartmann, G.: Introduction mycology by examples. Schering Aktienges — Sellschaft, Hamburg, 1980.

    Hartmann G. , '', in Introduction mycology by examples , (1980 ) -.

  • Larone, D. H.: Medically important fungi: A guide to identification. 3 rd Edition. ASMPress. Washington, DC, 1995.

    Larone D. H. , '', in Medically important fungi: A guide to identification , (1995 ) -.

  • de-Hoog, G. S., Guano, J., Gene, J., Figueras, M. J.: Atlas of Clinical Fungi, 2 nd edition, vol. 1. Centraal Bureau Voor Schimmelcultures, Utrecht, Netherlands, 2000.

    Figueras M. J. , '', in Atlas of Clinical Fungi , (2000 ) -.

  • Sanyal, A. K., Das, S. K., Banerjee, A. B.: Purification and partial characterization of an extracellular protease from Trichophyton rubrum . Sabouraudia 20 , 281–288 (1985).

    Banerjee A. B. , 'Purification and partial characterization of an extracellular protease from Trichophyton rubrum ' (1985 ) 20 Sabouraudia : 281 -288.

    • Search Google Scholar
  • Ekanem, L. S., Gugnani, H. C.: Etiology of dermatophytoses among school children in Cross River State of Nigeria. Mykosen 30 , 493–498 (1987).

    Gugnani H. C. , 'Etiology of dermatophytoses among school children in Cross River State of Nigeria ' (1987 ) 30 Mykosen : 493 -498.

    • Search Google Scholar
  • Zohdi, H. A. A., Youssef, Y. A., Abdel-Moneim, M. M. A, Forghaly, M. S., Eman, F. M., Abdallah, M. A.: Study of dermatophytes and dermatophytosis. Egyptian J Dermatol Vert 8 , 41–50 (1988).

    Abdallah M. A. , 'Study of dermatophytes and dermatophytosis ' (1988 ) 8 Egyptian J Dermatol Vert : 41 -50.

    • Search Google Scholar
  • Zaini, F., Chagan, A.: Epidemiological and mycological studies on tinea capitis at nurseries and school of Bander Chabahar. Iranian Public Health 18 , 39–43 (1989).

    Chagan A. , 'Epidemiological and mycological studies on tinea capitis at nurseries and school of Bander Chabahar ' (1989 ) 18 Iranian Public Health : 39 -43.

    • Search Google Scholar
  • Ogbonna, C. I. C., Robinson, R. O., Abubakar, J. M.: The distribution of ringworm infections among primary school children in Jos, Plateau State of Nigeria. Mycopathology 89 , 101–106 (1985).

    Abubakar J. M. , 'The distribution of ringworm infections among primary school children in Jos, Plateau State of Nigeria ' (1985 ) 89 Mycopathology : 101 -106.

    • Search Google Scholar
  • Nweze, E. I.: Etiology of dermatophytoses amongst children in Northeastern Nigeria. Med Mycol 39 , 181–184 (2001).

    Nweze E. I. , 'Etiology of dermatophytoses amongst children in Northeastern Nigeria ' (2001 ) 39 Med Mycol : 181 -184.

    • Search Google Scholar
  • Anosike, J. C., Kike, I. R., Uwaezuoke, J. C., Anozie, J. C., Obiakwu, C. E., Nwoke, B. E. B., Awajuoyi, O. U.: Prevalence and distribution of ringworm infections in primary school children in parts of Eastern Nigeria. JASEM 9 (3), 21–25 (2005).

    Awajuoyi O. U. , 'Prevalence and distribution of ringworm infections in primary school children in parts of Eastern Nigeria ' (2005 ) 9 JASEM : 21 -25.

    • Search Google Scholar
  • Awajuoyi, O. U.: Prevalence and distribution of ringworm infections in primary school children in parts of Eastern Nigeria. JASEM 9 (3): 21–25 (2005).

    Awajuoyi O. U. , 'Prevalence and distribution of ringworm infections in primary school children in parts of Eastern Nigeria ' (2005 ) 9 JASEM : 21 -25.

    • Search Google Scholar
  • Al-Sogair, S. M., Al-Humaidan, Y. M., Moawad, M. K.: Scalp fungus infection in the eastern province of Saudi Arabia. Ann Saudi Med 9 , 259–262 (1989).

    Moawad M. K. , 'Scalp fungus infection in the eastern province of Saudi Arabia ' (1989 ) 9 Ann Saudi Med : 259 -262.

    • Search Google Scholar
  • El-Benhawi, M. O., Fathy, S., Moubasher, A. H., Alem, N. S.: Mycologic study of tinea capitis in Qater. Int J Dermatol 30 , 204–205 (1991).

    Alem N. S. , 'Mycologic study of tinea capitis in Qater ' (1991 ) 30 Int J Dermatol : 204 -205.

    • Search Google Scholar
  • Seddon, M. E., Thomas, M. G.: Invasive disease due to Epidermophyton floccosum on an Immunocompromised patients with behest’s syndrome. Clinical Infections Diseases 25 , 153–154 (1997).

    Thomas M. G. , 'Invasive disease due to Epidermophyton floccosum on an Immunocompromised patients with behest’s syndrome ' (1997 ) 25 Clinical Infections Diseases : 153 -154.

    • Search Google Scholar
  • Nester, E. W., Anderson, D. G., Roberts, Jr., C. E., Pearsall, N. N., Nester, M. T.: Microbiology: A Human Perspective. 3 rd Edition, McGraw-Hill Company 2001, pp. 544–545.

  • Berger, T. G.: Baldness (Alopecia). In Mcphee, S. J., Papadakis, M. A., Tierney, Jr. L. M. (eds): Current Medical Diagnosis and Treatment, 46 th Edition. McGraw Hill Medical, 2007, pp. 145–146.

  • Paige, D. G.: Skin diseases — disorder of hair (Hair Loss). In Kumar, P., Clerk, M. (eds): Clinical Medicine. Elsevier Science Ltd. 2002, pp. 1315–1316.

  • Nelson, D. L., Cox, M. M.: Lehininger Principles of Biochemistry, 3 rd Edition. Worth Publishers, Madison Avenue, Newcastle 2000, pp. 163–166.

    Cox M. M. , '', in Lehininger Principles of Biochemistry , (2000 ) -.

 

The author instruction is available in PDF.
Please, download the file from HERE

Senior editors

Editor-in-Chief: Prof. Dóra Szabó (Institute of Medical Microbiology, Semmelweis University, Budapest, Hungary)

Managing Editor: Dr. Béla Kocsis (Institute of Medical Microbiology, Semmelweis University, Budapest, Hungary)

Co-editor: Dr. Andrea Horváth (Institute of Medical Microbiology, Semmelweis University, Budapest, Hungary)

Editorial Board

  • Prof. Éva ÁDÁM (Institute of Medical Microbiology, Semmelweis University, Budapest, Hungary)
  • Prof. Sebastian AMYES (Department of Medical Microbiology, University of Edinburgh, Edinburgh, UK.)
  • Dr. Katalin BURIÁN (Institute of Clinical Microbiology University of Szeged, Szeged, Hungary; Department of Medical Microbiology and Immunobiology, University of Szeged, Szeged, Hungary.)
  • Dr. Orsolya DOBAY (Institute of Medical Microbiology, Semmelweis University, Budapest, Hungary)
  • Prof. Ildikó Rita DUNAY (Institute of Inflammation and Neurodegeneration, Medical Faculty, Otto-von-Guericke University, Magdeburg, Germany; Center for Behavioral Brain Sciences (CBBS), Magdeburg, Germany)
  • Prof. Levente EMŐDY(Department of Medical Microbiology and Immunology, University of Pécs, Pécs, Hungary.)
  • Prof. Anna ERDEI (Department of Immunology, Eötvös Loránd University, Budapest, Hungary, MTA-ELTE Immunology Research Group, Eötvös Loránd University, Budapest, Hungary.)
  • Prof. Éva Mária FENYŐ (Division of Medical Microbiology, University of Lund, Lund, Sweden)
  • Prof. László FODOR (Department of Microbiology and Infectious Diseases, University of Veterinary Medicine, Budapest, Hungary)
  • Prof. József KÓNYA (Department of Medical Microbiology, University of Debrecen, Debrecen, Hungary)
  • Prof. Yvette MÁNDI (Department of Medical Microbiology and Immunobiology, University of Szeged, Szeged, Hungary)
  • Prof. Károly MÁRIALIGETI (Department of Microbiology, Eötvös Loránd University, Budapest, Hungary)
  • Prof. János MINÁROVITS (Department of Oral Biology and Experimental Dental Research, University of Szeged, Szeged, Hungary)
  • Prof. Béla NAGY (Centre for Agricultural Research, Institute for Veterinary Medical Research, Budapest, Hungary.)
  • Prof. István NÁSZ (Institute of Medical Microbiology, Semmelweis University, Budapest, Hungary)
  • Prof. Kristóf NÉKÁM (Hospital of the Hospitaller Brothers in Buda, Budapest, Hungary.)
  • Dr. Eszter OSTORHÁZI (Institute of Medical Microbiology, Semmelweis University, Budapest, Hungary)
  • Prof. Rozália PUSZTAI (Department of Medical Microbiology and Immunobiology, University of Szeged, Szeged, Hungary)
  • Prof. Peter L. RÁDY (Department of Dermatology, University of Texas, Houston, Texas, USA)
  • Prof. Éva RAJNAVÖLGYI (Department of Immunology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary)
  • Prof. Ferenc ROZGONYI (Institute of Laboratory Medicine, Semmelweis University, Budapest, Hungary)
  • Prof. Zsuzsanna SCHAFF (2nd Department of Pathology, Semmelweis University, Budapest, Hungary)
  • Prof. Joseph G. SINKOVICS (The Cancer Institute, St. Joseph’s Hospital, Tampa, Florida, USA)
  • Prof. Júlia SZEKERES (Department of Medical Biology, University of Pécs, Pécs, Hungary.)
  • Prof. Mária TAKÁCS (National Reference Laboratory for Viral Zoonoses, National Public Health Center, Budapest, Hungary.)
  • Prof. Edit URBÁN (Department of Medical Microbiology and Immunology University of Pécs, Pécs, Hungary; Institute of Translational Medicine, University of Pécs, Pécs, Hungary.)

 

Editorial Office:
Akadémiai Kiadó Zrt.
Budafoki út 187-187, A/3, H-1117 Budapest, Hungary

Editorial Correspondence:
Acta Microbiologica et Immunologica Hungarica
Institute of Medical Microbiology
Semmelweis University
P.O. Box 370
H-1445 Budapest, Hungary
Phone: + 36 1 459 1500 ext. 56101
Fax: (36 1) 210 2959
E-mail: amih@med.semmelweis-univ.hu

 Indexing and Abstracting Services:

  • Biological Abstracts
  • BIOSIS Previews
  • CAB Abstracts
  • Chemical Abstracts
  • Global Health
  • Index Medicus
  • Index Veterinarius
  • Medline
  • Referativnyi Zhurnal
  • SCOPUS
  • Science Citation Index Expanded
2020  
Total Cites 662
WoS
Journal
Impact Factor
2,048
Rank by Immunology 145/162(Q4)
Impact Factor Microbiology 118/137 (Q4)
Impact Factor 1,904
without
Journal Self Cites
5 Year 0,671
Impact Factor
Journal  0,38
Citation Indicator  
Rank by Journal  Immunology 146/174 (Q4)
Citation Indicator  Microbiology 120/142 (Q4)
Citable 42
Items
Total 40
Articles
Total 2
Reviews
Scimago 28
H-index
Scimago 0,439
Journal Rank
Scimago Immunology and Microbiology (miscellaneous) Q4
Quartile Score Medicine (miscellaneous) Q3
Scopus 438/167=2,6
Scite Score  
Scopus General Immunology and Microbiology 31/45 (Q3)
Scite Score Rank  
Scopus 0,760
SNIP
Days from  225
sumbission
to acceptance
Days from  118
acceptance
to publication
Acceptance 19%
Rate

2019  
Total Cites
WoS
485
Impact Factor 1,086
Impact Factor
without
Journal Self Cites
0,864
5 Year
Impact Factor
1,233
Immediacy
Index
0,286
Citable
Items
42
Total
Articles
40
Total
Reviews
2
Cited
Half-Life
5,8
Citing
Half-Life
7,7
Eigenfactor
Score
0,00059
Article Influence
Score
0,246
% Articles
in
Citable Items
95,24
Normalized
Eigenfactor
0,07317
Average
IF
Percentile
7,690
Scimago
H-index
27
Scimago
Journal Rank
0,352
Scopus
Scite Score
320/161=2
Scopus
Scite Score Rank
General Immunology and Microbiology 35/45 (Q4)
Scopus
SNIP
0,492
Acceptance
Rate
16%

 

Acta Microbiologica et Immunologica Hungarica
Publication Model Online only Hybrid
Submission Fee none
Article Processing Charge 1100 EUR/article
Regional discounts on country of the funding agency World Bank Lower-middle-income economies: 50%
World Bank Low-income economies: 100%
Further Discounts Editorial Board / Advisory Board members: 50%
Corresponding authors, affiliated to an EISZ member institution subscribing to the journal package of Akadémiai Kiadó: 100%
Subscription Information Online subsscription: 652 EUR / 812 USD
Online subscribers are entitled access to all back issues published by Akadémiai Kiadó for each title for the duration of the subscription, as well as Online First content for the subscribed content.
Purchase per Title Individual articles are sold on the displayed price.

Acta Microbiologica et Immunologica Hungarica
Language English
Size A4
Year of
Foundation
1954
Publication
Programme
2021 Volume 68
Volumes
per Year
1
Issues
per Year
4
Founder Magyar Tudományos Akadémia
Founder's
Address
H-1051 Budapest, Hungary, Széchenyi István tér 9.
Publisher Akadémiai Kiadó
Publisher's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Responsible
Publisher
Chief Executive Officer, Akadémiai Kiadó
ISSN 1217-8950 (Print)
ISSN 1588-2640 (Online)

Monthly Content Usage

Abstract Views Full Text Views PDF Downloads
Feb 2021 5 0 0
Mar 2021 7 0 0
Apr 2021 1 0 0
May 2021 6 0 0
Jun 2021 2 0 0
Jul 2021 28 0 0
Aug 2021 0 0 0