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  • 1 University of Extremadura Neuroimmunophysiology and Chrononutrition Research Group, Department of Physiology Badajoz Spain
  • 2 University of Extremadura Laboratory of Health Education, Experimental Sciences Education Area Av/de Elvas S/N CP: 06006 Badajoz Spain
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Sleep deprivation affects the homeostasis of the physiological functions in the human organism. Beer is the only beverage that contains hops, a plant which has a sedative effect. Our objective is to determine the improvement of subjective sleep quality using the Pittsburgh Sleep Quality Index (PSQI). The sample was conducted among a population of 30 university students. The study took place during a period of 3 weeks, the first 7 days were used for the Control, and during the following 14 days the students ingested beer (were asked to drink non-alcoholic beer) while having dinner. The results revealed that Subjective Sleep Quality improved in the case of those students who drank one beer during dinner compared to the Control, this is corroborated by the fact that Sleep Latency decreased (p < 0.05) compared to their Control. The overall rating Global Score of Quality of Sleep also improved significantly (p < 0.05). These results confirm that the consumption of non-alcoholic beer at dinner time helps to improve the quality of sleep at night.

  • Abourashed EA, Koetter U, Brattstrom A: In vitro binding experiments with a valerian, hops and the fixed combination extract (Ze91019) to selected central nervous system receptor. Phytomedicine 11, 633–638 (2004)

    Brattstrom A. , 'In vitro binding experiments with a valerian, hops and the fixed combination extract (Ze91019) to selected central nervous system receptor ' (2004 ) 11 Phytomedicine : 633 -638.

    • Search Google Scholar
  • Aoshima H, Takeda K, Okita Y, Sheikh Julfikar H, Koda H, Yoshinobu K: Effects of beer and hop on ionotropic γ-aminobutyric acid receptors. J. Agric. Food Chem. 54 2514–1519 (2006)

    Yoshinobu K. , 'Effects of beer and hop on ionotropic γ-aminobutyric acid receptors ' (2006 ) 54 J. Agric. Food Chem. : 2514 -1519.

    • Search Google Scholar
  • Arnedt JT, Owens J, Crouch M, Stahl J, Carskadon MA: Neurobehavioral performance of residents after heavy night call vs. after alcohol ingestion. JAMA 294, 1025–1033 (2005)

    Carskadon M.A. , 'Neurobehavioral performance of residents after heavy night call vs. after alcohol ingestion ' (2005 ) 294 JAMA : 1025 -1033.

    • Search Google Scholar
  • Bellini LM, Baime M, Shea JA: Variation of mood and empathy during internship. JAMA 287, 3143–3146 (2002)

    Shea J.A. , 'Variation of mood and empathy during internship ' (2002 ) 287 JAMA : 3143 -3146.

  • Bellini LM, Shea JA: Mood change and empathy decline persist during three years of internal medicine training. Acad. Med. 80, 164–167 (2005)

    Shea J.A. , 'Mood change and empathy decline persist during three years of internal medicine training ' (2005 ) 80 Acad. Med. : 164 -167.

    • Search Google Scholar
  • Bonnet MH: Effect of sleep disruption on sleep, performance, and mood. Sleep. 8, 11–19 (1985)

    Bonnet M.H. , 'Effect of sleep disruption on sleep, performance, and mood ' (1985 ) 8 Sleep : 11 -19.

    • Search Google Scholar
  • Carskadon MA: Patterns of sleep and sleepiness in adolescents. Pediatrician 17, 5–12 (1990)

    Carskadon M.A. , 'Patterns of sleep and sleepiness in adolescents ' (1990 ) 17 Pediatrician : 5 -12.

    • Search Google Scholar
  • Curcio G, Ferrara M, De Gennaro L: Sleep loss, learning capacity and academic performance. Sleep Med. Rev. 10, 323–337 (2006)

    Gennaro L. , 'Sleep loss, learning capacity and academic performance ' (2006 ) 10 Sleep Med. Rev. : 323 -337.

    • Search Google Scholar
  • Dimpfel W, Suter A: Sleep improving effects of a single dose administration of valerians/hops fluid extract-a double blind, randomized, placebo-controlled sleep-EEG study in parallel design using electrohypnograms. Eur. J. Med. Res. 26, 200–204 (2008)

    Suter A. , 'Sleep improving effects of a single dose administration of valerians/hops fluid extract-a double blind, randomized, placebo-controlled sleep-EEG study in parallel design using electrohypnograms ' (2008 ) 26 Eur. J. Med. Res. : 200 -204.

    • Search Google Scholar
  • Franco L, Sánchez C, Bravo R, Rodriguez AB, Barriga C, Romero E, Cubero J: The sedative effects of nonalcoholic beer in healthy female nurses. PLOS ONE 7 (2012)

    Cubero J. , '', in PLOS ONE , (2012 ) -.

  • Franco L, Sanchez C, Bravo R, Rodriguez A, Barriga C: The sedative effects of hops (Humulus lupulus), a component of beer, on the activity/rest rhythm. Acta Physiol. Hung. 99, 133–139 (2012)

    Barriga C. , 'The sedative effects of hops (Humulus lupulus), a component of beer, on the activity/rest rhythm ' (2012 ) 99 Acta Physiol. Hung. : 133 -139.

    • Search Google Scholar
  • García López P, Capote Gil F, Quintana Gallego ME: Valoración mediante escala de Epworth de la somnolencia diurna en pacientes con sospecha de síndrome de apneas obstructivas durante el sueño. Diferencias entre los pacientes y sus parejas. (Assessment, through Epworth’s scale, of diurnal sleepiness in patients that may have obstructive apnea syndrome during sleep. Differences between patients and their partners) Arch. Bronconeumol. 36, 608–611 (2000)

    Quintana Gallego M.E. , 'Valoración mediante escala de Epworth de la somnolencia diurna en pacientes con sospecha de síndrome de apneas obstructivas durante el sueño. Diferencias entre los pacientes y sus parejas ' (2000 ) 36 Arch. Bronconeumol. : 608 -611.

    • Search Google Scholar
  • Greene R, Siegel J: Sleep: a functional enigma. Neuromolecular Med. 5, 59–68. Review (2004)

    Siegel J. , 'Sleep: a functional enigma ' (2004 ) 5 Neuromolecular Med. : 59 -68.

  • Hänsel R, Wohlfart R, Coper H: Sedative-hypnotic compounds in the exhalation of hops, II. Z. Naturforsch. C. 35, 1096–1097 (1980)

    Coper H. , 'Sedative-hypnotic compounds in the exhalation of hops, II ' (1980 ) 35 Z. Naturforsch. C. : 1096 -1097.

    • Search Google Scholar
  • Howard SK (2000): Sleep deprivation and fatigue. In: Miller RD: Anesthesia, 5th edition, Philadelphia, Churchill Livingstone, pp. 2637–2646

    Howard S.K. , '', in Anesthesia , (2000 ) -.

  • Hsu Wen, Chiu Nan, Liu Jui, Wang Chieh, Chang Ting, Laido Yi, Kuo Pei: Sleep quality in heroin addicts under methadone manintence treatment. Acta Neuropsychiatr. 24, 356–360 (2012)

    Kuo P. , 'Sleep quality in heroin addicts under methadone manintence treatment ' (2012 ) 24 Acta Neuropsychiatr. : 356 -360.

    • Search Google Scholar
  • Jimenez-Genchi A, Monteverde-Maldonado E, Nenclares-Portocarrero A, Esquivel-Adame G, de la Vega-Pacheco A: Reliably and factorial analysis of the Spanish version of the Pittsburg Sleep Quality Index among psychiatric patients. Gac. Med. Mex. 144, 491–496 (2008)

    Vega-Pacheco A. , 'Reliably and factorial analysis of the Spanish version of the Pittsburg Sleep Quality Index among psychiatric patients ' (2008 ) 144 Gac. Med. Mex. : 491 -496.

    • Search Google Scholar
  • Killgore WDS, Balkin TJ, Wesensten NJ: Impaired decision making following 49 h of sleep deprivation. J. Sleep Res. 15, 7–13 (2006)

    Wesensten N.J. , 'Impaired decision making following 49 h of sleep deprivation ' (2006 ) 15 J. Sleep Res. : 7 -13.

    • Search Google Scholar
  • Killgore WDS, Killgore DB, Day LM, Li C, Kamimori GH, Balkin TJ: The effects of 53 hours of sleep deprivation on moral judgment. Sleep 30, 345–352 (2007)

    Balkin T.J. , 'The effects of 53 hours of sleep deprivation on moral judgment ' (2007 ) 30 Sleep : 345 -352.

    • Search Google Scholar
  • Koether U, Schrader E, Kaufeler R, Brattstrom A: A randomized double blind, placebo-controlled, prospective clinical efficacy of fixed valerian hops extract combination (Ze 91019) in patients suffering from non-organic sleep disorder. Phytother. Res. 21, 847–851 (2007)

    Brattstrom A. , 'A randomized double blind, placebo-controlled, prospective clinical efficacy of fixed valerian hops extract combination (Ze 91019) in patients suffering from non-organic sleep disorder ' (2007 ) 21 Phytother. Res. : 847 -851.

    • Search Google Scholar
  • Lee KM, Jung KS, Song DK, Krauter M, Kim HY: Effects of Humulus lupulus extract on the central nervous system in mice. Planta Med. 59(Suppl): A691 (1993)

    Kim H.Y. , 'Effects of Humulus lupulus extract on the central nervous system in mice ' (1993 ) 59 Planta Med. : A691 -.

    • Search Google Scholar
  • Maldonado M, Moreno H, Calvo JR: Melatonin present in beer contributes to increase the levels of melatonin and antioxidant capacity of the human serum. Clin. Nutr. 28, 188–191 (2009)

    Calvo J.R. , 'Melatonin present in beer contributes to increase the levels of melatonin and antioxidant capacity of the human serum ' (2009 ) 28 Clin. Nutr. : 188 -191.

    • Search Google Scholar
  • Marín HA, Sosa S, Vivanco D, Aristizábal N, Berrio MC, Vinaccia S: Factores culturales que privan el sueño y causan somnolencia excesiva en estudiantes universitarios: un estudio piloto. (Cultural factors that deprive sleep and cause excessive sleepiness in university students: a pilot study) Psicol.Salud. 15, 57–68 (2005)

    Vinaccia S. , 'Factores culturales que privan el sueño y causan somnolencia excesiva en estudiantes universitarios: un estudio piloto ' (2005 ) 15 Psicol.Salud. : 57 -68.

    • Search Google Scholar
  • Meissner O, Haberlein H: Influence of xanthohumol on the binding behaviour of GABAA receptors and their lateral mobility at hippocampal neurons. Planta Med. 72, 656–658 (2006)

    Haberlein H. , 'Influence of xanthohumol on the binding behaviour of GABAA receptors and their lateral mobility at hippocampal neurons ' (2006 ) 72 Planta Med. : 656 -658.

    • Search Google Scholar
  • Philibert I: Sleep loss and performance in residents and nonphysicians: a meta-analytic examination. Sleep 28, 1392–1402 (2005)

    Philibert I. , 'Sleep loss and performance in residents and nonphysicians: a meta-analytic examination ' (2005 ) 28 Sleep : 1392 -1402.

    • Search Google Scholar
  • Pilcher JJ, Huffcutt AI: Effects of sleep deprivation on performance: a meta-analysis. Sleep 19, 318–326 (1996)

    Huffcutt A.I. , 'Effects of sleep deprivation on performance: a meta-analysis ' (1996 ) 19 Sleep : 318 -326.

    • Search Google Scholar
  • Posada J (1998): Estudio recopilatorio Cerveza y Salud. Escuela Superior de Cerveza y Malta. (Beer and Health compilation study. Higher School of Beer and Malt). ESCEMA. Madrid. Spain

    Posada J. , '', in Estudio recopilatorio Cerveza y Salud. Escuela Superior de Cerveza y Malta , (1998 ) -.

  • Rey de Castro J, Vizcarra D, Álvarez J: Somnolencia diurna y síndrome apnea hipopnea del sueño-asociación entre parámetros antropométricos y puntaje Epworth en polisomnografía convencional y de noche partida. (Diurnal sleepiness and apnea hypopnea sleep syndrom- associaton between anthropometric parameters and Epworth’s score in conventional polysleepinessgrafy and of part night). Rev. Soc. Peru Med. Interna.16, 74–83 (2003)

    Álvarez J. , 'Somnolencia diurna y síndrome apnea hipopnea del sueño-asociación entre parámetros antropométricos y puntaje Epworth en polisomnografía convencional y de noche partida ' (2003 ) 16 Rev. Soc. Peru Med. Interna. : 74 -83.

    • Search Google Scholar
  • Rey de Castro J, Vizcarra D: Limited value of Epworth Modified Scale for hipersomnia assessment in 57 patients submited to polisomnography. 24th International Congress of Internal Medicine, PS 134 (1998)

    Vizcarra D. , '', in 24th International Congress of Internal Medicine , (1998 ) -.

  • Rodrigues RND, Viegas CAA, Abreu e Silva AAA, Tavares P: Daytime sleepiness and academic performance in medical students. Arq. Neuropsiquiatr. 60, 6–11 (2002)

    Tavares P. , 'Daytime sleepiness and academic performance in medical students ' (2002 ) 60 Arq. Neuropsiquiatr. : 6 -11.

    • Search Google Scholar
  • Salter S, Brownie S: Treating primary insomnia — the efficacy of valerian and hops. Aust. Fam. Physician. 39, 433–437 (2010)

    Brownie S. , 'Treating primary insomnia — the efficacy of valerian and hops ' (2010 ) 39 Aust. Fam. Physician. : 433 -437.

    • Search Google Scholar
  • Sánchez CL, Franco L, Bravo R, Rubio C, Rodríguez AB; Barriga C, Cubero J: Cerveza y salud, beneficios en el sueño (Beer and health, benefits in sleep). Rev. Esp. Nutr. Comunitaria. 13, 160–163 (2010)

    Cubero J. , 'Cerveza y salud, beneficios en el sueño ' (2010 ) 13 Rev. Esp. Nutr. Comunitaria. : 160 -163.

    • Search Google Scholar
  • Schellenberg R, Sauer S, Abourashed E, Koetter U, Brattstrom A: The fixed combination of valerian and hops (Ze91019) acts via a central adenosine mechanism. Planta Med. 70, 594–597 (2004)

    Brattstrom A. , 'The fixed combination of valerian and hops (Ze91019) acts via a central adenosine mechanism ' (2004 ) 70 Planta Med. : 594 -597.

    • Search Google Scholar
  • Schmitz M, Jackel M: Comparative study for assessing quality of life of patients with exogenous sleep disorders (temporary sleep onset and sleep interruption disorders) treated with hops-valerian preparation and benzodiazepine drug. Wien Med. Wochenschr. 148, 291–298 (1998)

    Jackel M. , 'Comparative study for assessing quality of life of patients with exogenous sleep disorders (temporary sleep onset and sleep interruption disorders) treated with hops-valerian preparation and benzodiazepine drug ' (1998 ) 148 Wien Med. Wochenschr. : 291 -298.

    • Search Google Scholar
  • Sierra JC, Jiménez-Navarro C, Martín-Ortíz JD: Calidad del sueño en estudiantes universitarios: importancia de la higiene del sueño (Sleep quality in universitary students: the importance of the sleep higiene). Salud Mental. 25, 35–43 (2002)

    Martín-Ortíz J.D. , 'Calidad del sueño en estudiantes universitarios: importancia de la higiene del sueño ' (2002 ) 25 Salud Mental. : 35 -43.

    • Search Google Scholar
  • Smith-Coggins R, Rosekind MR, Hurd S, Buccino KR: Relationship of day versus night sleep to physician performance and mood. Ann. Emerg. Med. 24, 959–961 (1994)

    Buccino K.R. , 'Relationship of day versus night sleep to physician performance and mood ' (1994 ) 24 Ann. Emerg. Med. : 959 -961.

    • Search Google Scholar
  • Spielberger CD, Gorsuch RL, Lushene RE (2008): Cuestionario de Ansiedad Estado-Rasgo. (Survey about Condition-Characteristic Anxiety). C.D. Madrid

    Lushene R.E. , '', in Cuestionario de Ansiedad Estado-Rasgo , (2008 ) -.

  • Vonderheid-Guth B, Todorova A, Brattstrom A, Dimpfel W: Pharmacodynamic effects of valerian and hops extract combination (Ze 91019) on the quantitative-topographical EEG in the healthy volunteers. Eur. J. Med. Res. 5, 139–144 (2000)

    Dimpfel W. , 'Pharmacodynamic effects of valerian and hops extract combination (Ze 91019) on the quantitative-topographical EEG in the healthy volunteers ' (2000 ) 5 Eur. J. Med. Res. : 139 -144.

    • Search Google Scholar
  • Weeks BS: Formulations of dietary supplements and herbal extracts for relaxation and anxiolytic action: Relarian. Med. Sci. Monit. 15, 256–262 (2009)

    Weeks B.S. , 'Formulations of dietary supplements and herbal extracts for relaxation and anxiolytic action: Relarian ' (2009 ) 15 Med. Sci. Monit. : 256 -262.

    • Search Google Scholar
  • Weinger MB, Ancoli-Israel S: Sleep deprivation and clinical performance. JAMA 287, 955–957 (2002)

    Ancoli-Israel S. , 'Sleep deprivation and clinical performance ' (2002 ) 287 JAMA : 955 -957.

  • Wiggins CL, Schmidt-Nowara WW, Coultas DB, Samet JM: Comparation of self and spouse reports of snoring and other symptoms associated with sleep apnea syndrome. Sleep 13, 245–252 (1990)

    Samet J.M. , 'Comparation of self and spouse reports of snoring and other symptoms associated with sleep apnea syndrome ' (1990 ) 13 Sleep : 245 -252.

    • Search Google Scholar
  • Wohlfart R, Hansel R, Schmidt H: The sedative-hypnotic principle of hops. 4. Pharmacology of the hop substance 2-methyl-3-buten-ol. Planta Med. 48, 120–123 (1983)

    Schmidt H. , 'The sedative-hypnotic principle of hops. 4. Pharmacology of the hop substance 2-methyl-3-buten-ol ' (1983 ) 48 Planta Med. : 120 -123.

    • Search Google Scholar
  • Yasuhiro I, Nakayama A, Kanbe H, Miwako K, Saito Y, Adachi M, Kondo N, Tadayuki I: A knowledge about the relationship between dietary habits and sleep quality. J. Anal. Bio-Science 36, 2 181–185 (2013)

    Tadayuki I. , 'A knowledge about the relationship between dietary habits and sleep quality ' (2013 ) 36 J. Anal. Bio-Science : 181 -185.

    • Search Google Scholar
  • Zanoli P, Zavatti M, Rivasi M, Brusiani F, Losi G, Puia R, Avallone R, Baraldi M: Evidence that the β-acids fraction of hops reduces central GABAergic neurotransmission. J. Ethnopharmacol. 109, 87–92 (2007)

    Baraldi M. , 'Evidence that the β-acids fraction of hops reduces central GABAergic neurotransmission ' (2007 ) 109 J. Ethnopharmacol. : 87 -92.

    • Search Google Scholar
  • Zanoli P, Zavatti M: Pharmacognostic and pharmacological profile of Humulus lupulus L. J. Ethnopharmacol. 116, 383–396 (2008)

    Zavatti M. , 'Pharmacognostic and pharmacological profile of Humulus lupulus L. ' (2008 ) 116 J. Ethnopharmacol. : 383 -396.

    • Search Google Scholar

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