Cultivated mushrooms are not only valuable foods of our age (functional foods) but contain certain beneficial chemical components (high level of K and P, very low content of Na, considerable quantities of some microelements, high and valuable protein but low fat contents). Some cultivated mushrooms have anti-carcinogenic effects caused first of all by polysaccharides (Lentinan: Lentinula edodes) and by triterpenoids (ganoderic acids: Ganoderma lucidum or unsaturated fatty acids: linoleic, linolenic acids); antidiabetic effects, which can improve the sugar metabolism of patients (Coprinus comatus, Ganoderma lucidum, Agaricus bisporus); anti-microbial effects, caused partly by smaller triterpenoids or by higher molecules, i.e. by direct or indirect effects: via stimulation of the immune system. Certain mushrooms have antioxidant effects, provided mostly by higher radical scavenging activity of phenolic (flavonoid) components. The chemical composition and its biological effects form together the biological values of the cultivated mushrooms.
The following review would like to summarize the most important facts of this topic.
Agrawal, R.P., Chopra, G., Lavekar, G.S., Padhi, M.M., Srikanth, N., Ota, S. & Jain, S. (2010): Effect of oyster mushroom on glycemia, lipid profile and quality of life in type 2 diabetic patients. Aust. J. Med. Herbalism, 22, 50–54.
Bauer-Petrowska, B. (2001): Protein fractions in edible Macedonian mushrooms. Eur. Food Res. Technol., 212, 469–472.
Bernas, E., Jaworska, G. & Lisiewska, Z. (2006): Edible mushrooms as a source of valuable nutritive constituents. Acta Sci. Pol. Technol. Aliment., 5, 5–20.
Chen, S., Oh, S., Phung, S., Hur, G., Ye, J.J., …. & Williams, D. (2006): Anti-aromatase activity of phytochemicals in white button mushrooms (Agaricus bisporus). Cancer Res., 66, 12026–12034.
Cheng, S.J. & Sliva, D. (2015): Ganoderma lucidum for cancer treatment: We are close but still not there. Integr. Cancer Ther., 14, 249–257.
Cheung, P.C.K. (2008): Nutritional value and health benefits of mushrooms. -in: Cheung, P.C.K. (Ed.) Mushrooms as functional foods. John Wiley and Sons Inc., Hoboken, New Jersey, USA, pp. 71–110.
Cheung, P.C.K. (2013): Mini-review on edible mushrooms as source of dietary fiber: Preparation and health benefits. Food Science and Human Wellness, 2, 162–166.
Chihara, G., Hamuro, J., Maeda, Y.Y., Arai, Y. & Fukuoka, F. (1970): Fractionation and purification of the polysaccharides with marked antitumor activity, especially lentinan from Lentinus edodes (Berk.) Sing. (an edible mushroom). Cancer Res., 30, 2776–2781.
De Silva, D.D., Rapior, S., Hyde, K.D. & Bahkali, A.H. (2012): Medicinal mushrooms in prevention and control of diabetes mellitus. Fungal Divers., 56, 1–29.
Del Toro, G.V., Vega, R.C., Garin-Aquilar, M.E. & Lara, H.L. (2006): Biological quality of proteins from three strains of Pleurotus spp. Food Chem. Food Chem., 94, 494–497.
Dikeman, C.L., Bauer, L.L., Flickinger, E.A. & Fahey, G.C. Jr. (2005): Effects of stage and maturity and cooking on the chemical composition of select mushroom varieties. J. Agr. Food Chem., 53, 1130–1138.
Ding, Z.Y., Lu, Y.J., Lu, Z.X., Iv, F.X., Wang, Y.H., Bei, X.M., Wang, F. & Zhang, K.C. (2010): Hypoglycaemic effect of comatin, an antidiabetic substance separated from Coprinus comatus broth, on alloxan induced-diabetic rats. Food Chem., 121, 39–43.
Gao, Y., Lan, J., Dai, X., Ye, J. & Zhou, S. (2004): A phase I/II study of lingzhi mushroom Ganoderma lucidum (W. Curt.:Fr.) Lloyd (Aphyllophoromycetidae) extract in patients with type II diabetes mellitus. Int. J. Med. Mushrooms, 6, 33–39.
Ghaly, I.S., Ahmed, E.S., Booles, H.F., Farag, I.M. & Nada, S.A. (2011): Evaluation of antihyperglycemic action of oyster mushroom (Pleurotus ostreatus) and its effect on DNA damage, chromosome aberrations and sperm abnormalities in streptozotocin-induced diabetic rats. Global Veterinaria, 7, 532–544.
Ghorai, S., Banik, S.P., Verma, D., Chowdury, S., Mukherjee, S. & Khowala, S. (2009): Fungal biotechnology in food and feed processing. Food Res. Int., 42, 577–587.
Györfi, J., Geösel, A. & Vetter, J. (2010): Mineral composition of different strains of edible medicinal mushroom Agaricus subrufescens Peck. J. Med. Food, 13, 1510–1514.
Higaki, M., Eguchi, F., Zhang, J., Kikukawa, T., Abe, C., Kato, K., Hasegawa, K. & Watanabe, Y. (2005): Improvement of pancreatic beta-cells by hot water extract from cultured Agaricus blazei (CJ-01) fruiting bodies in GK rats. J. Tradit. Med., 17, 205–214.
Hong, L., Xun, M. & Wutong, W. (2007): Anti-diabetic effect of an alfa-glucan from fruit body of maitake (Grifola frondosa) on KK-Ay mice. J. Pharm. Pharmacol., 59, 575–582.
Hung, P.V. & Nhi, N.Y. (2012): Nutritional composition and antioxidant capacity of several edible mushrooms grown in the Southern Vietnam. Int. Food Res. J., 19, 611–615.
Jagadish, L.K., Krishnan, V.V., Shenbhagaraman, R. & Kaviyarasan, V. (2009): Comparative study on the antioxidant, anticancer and antimicrobial property of Agaricus bisporus (J.E. Lange) Imbach before and after boiling. Afr. J. Biotechnol., 8, 654–661.
Jasinghe, V.J., Perera, C.O. & Barlow, P.J. (2005): Bioavailability of vitamin D2 from irradiated mushrooms: An in vivo study. Brit. J. Nutr., 93, 951–955.
Jedinak, A., Thyagarajan-Sahu, A., Jiang, J. & Sliva, D. (2011): Ganodermanotriol, a lanostanoid triterpene from Ganoderma lucidum, suppresses growth and colon cancer cells through ss-catenin signalling. Int. J. Oncol., 38, 761–767.
Jeong, S.C., Jeong, Y.T., Yang, B.K., Islam, R., Koyyalamudi, S.R., Pang, G., Cho, K.Y. & Song, C.H. (2010): White button mushroom (Agaricus bisporus) lowers blood glucose and cholesterol levels in diabetic and hypercholesterolemic rats. Nutr. Res., 30, 49–56.
Kalac, P. (2012): A review of chemical composition and nutritional value of wild-growing and cultivated mushrooms. J. Sci. Food Agr., 93, 209–218.
KALAC, P. (2016): Edible mushrooms. Chemical composition and nutritional value. Elsevier, Amsterdam, Tokyo. p. 207.
Kalac, P. & Svoboda, L. (2000): A review of trace element concentrations in edible mushrooms. Food Chem., 69, 273–281.
Kao, C.H.J., Jesuthasan, A.C., Bishop, K.S., Glucina, M.P. & Ferguson, L.R. (2013): Anti-cancer activities of Ganoderma lucidum: Active ingredients and pathways. Functional Foods in Health and Disease (FFHD), 3, 48–65.
Kawagishi, H., Inagaki, R., Kanao, T., Mizuno, T., Shimura, K., Ito, H., Hagiwara, T. & Nakamura, T. (1989): Fractionation and antitumor activity of the water-insoluble residue of Agaricus blazei fruiting bodies. Carbohyd. Res., 186, 267–273.
Khan, A. & Tania, M. (2012): Nutritional and medicinal importance of Pleurotus mushrooms: An overview. Food Rev. Int., 28, 313–329.
Kim, S.K., Hong, U.P., Kim, J.S., Kim, C.H., Lee, K.W., Choi, S.E., Park, K.H. & Lee, M.W. (2007): Antidiabetic effect of Auricularia auricula mycelia in streptozotocin-induced diabetic rats. Natural Product Sciences, 13, 390–393.
Krüzselyi, D., Kovács, D. & Vetter, J. (2016): Chemical analysis of king oyster mushroom (Pleurotus eryngii) fruit bodies. Acta Alimentaria, 45, 20–27.
Lelley, J. & Vetter, J. (2005): The possible role of mushrooms in maintaining good health and preventing diseases. -in: Mushroom biology and mushroom products, Proceedings of the Fifth International Conference on Mushroom Biology and Mushroom Products 8–12 April 2005, Shanghai China, pp. 412–419.
Lisiecka, J., Sobieralski, K., Siwulski, M. & Jasinska, A. (2013): Almond mushroom Agaricus brasiliensis (Wasser et al.) Properties and culture conditions. Acta Sci. Pol. Hortoru., 12, 27–40.
Manzi, P. & Pizzoferrato, L. (2000): Beta-glucans in edible mushrooms. Food Chem., 68, 315–318.
Mattila, P., Könkö, K., Eurola, M., Pihlava, J.M., Astola, J. & Vahteristo, L. (2001): Contents of vitamins, mineral elements and some phenolic compounds in cultivated mushrooms. J. Agr. Food Chem., 49, 2343–2348.
Pardo-Gimenez, A., Figueiredo, V.R., Dias, E.S., Pardo-Gonzalez, J.E., Alvarez-Orti, M. & Zied, D.C. (2013): Proximate analysis of sporophores of Agaricus subrufescens Peck. ITEA Inf. Tec. Econ. Ag., 109, 290–302.
Roberfroid, M.B. (2002): Global view on functional foods: European perspectives. Brit. J. Nutr., 88, 133–138.
Royse, D.J. (2014): A global perspective on the high five: Agaricus, Pleurotus, Lentinula, Auricularia & Flammulina. Proceedings of the 8th International Conference on Mushroom Biology and Mushroom Products (ICMBMP8), pp. 1–6.
Sales-Campos, C., Araujo, L.M., Minhoni, M.T.A. & Andrade, M.C.N. (2011): Physicochemical analysis and centesimal composition of Pleurotus ostreatus mushroom grown in residues from the Amazon. Cienc. Tecnol. Aliment., 31, 456–461.
Seto, S.W., Lam, T.Y., Tam, H.L., Au, A.L., Chan, S.W., … & Kwan, Y.W. (2009): Novel hypoglycemic effects of Ganoderma lucidum water-extract in obese/diabetic (+db/+db) mice. Phytomedicine, 16, 426–436.
Stajic, M., Vukojevic, J. & Duletic-Lausevic, S. (2009): Biology of Pleurotus eryngii and role in biotechnological processes: A review. Crit. Rev. Biotechnol., 29, 55–66.
Stijve, T., Amazonas, M. & Giller, V. (2002): Flavour and taste components of Agaricus blazei ss. Heinem — A new gourmet and medicinal mushroom. Deut. Lebensm.-Rundsch., 98, 448–453.
Sun, J., He, H. & Xie, B.J. (2004): Novel antioxidant peptides from fermented mushroom Ganoderma lucidum. J. Agr. Food Chem., 52, 6646–6652.
Synytsya, A., Mickova, K., Jablonsky, I., Slukova, M. & Copikova, J. (2008): Mushrooms of genus Pleurotus as a source of dietary fibres and glucans for good supplements. Czech. J. Food Sci., 26, 441–446.
Taofiq, O., Fernandes, A., Barros, L., Barreiro, M.F. & Ferreira, I.C.F.R. (2017): UV-irradiated mushrooms as a source of vitamin D2: A review. Trends Food Sci. Tech., 70, 82–94.
Tsai, S.Y., Huang, S.J., Lo, S.H., Wu, T.P., Lian, P.Y. & Mau, J.L. (2009): Flavour components and antioxidant properties of several cultivated mushrooms. Food Chem., 113, 578–584.
Ulziijargal, E. & Mau, J.L. (2011): Nutrient composition of culinary-medicinal mushroom fruiting bodies and mycelia. Int J. Med. Mushrooms, 13, 343–349.
Vetter, J. (1994): Data on arsenic and cadmium contents of some common mushrooms. Toxicon, 32, 11–15.
Vetter, J. (1996): Vanadium content of wild growing edible mushrooms. Clusiana, 35, 37–46.
Vetter, J. (2007): Chitin content of cultivated mushrooms Agaricus bisporus, Pleurotus ostreatus and Lentinula edodes. Food Chem., 102, 6–9.
Vetter, J. (2010): A gombák táplálkozási értékei (Nutritional value of mushrooms). -in: Györfi, J. (Ed.) Gombabiológia — Gombatermesztés (Biology of mushrooms — Mushroom cultivation). Mezőgazda Kiadó, Budapest, pp. 48–63.
Vetter, J. & Lelley, J. (2004): Selenium level of the cultivated mushroom Agaricus bisporus. Acta Alimentaria, 33, 297–301.
Vetter, J. & Rimóczi, I. (1993): Crude, digestible and non-digestible proteins in fruit bodies of Pleurotus ostreatus (oyster mushroom). Z. Lebensm. Unters. For., 197, 427–428.
Wang, Y. & Xu, B. (2014): Distribution of antioxidant activities and total phenolic contents in acetone, ethanol, water and hot water extracts from 20 edible mushrooms via sequential extraction. Austin J. Nutr. Food Sci., 2, 1009–1014.
Wasser, S.P. & Weiss, L. (1999): Medicinal properties of substances in higher Basidiomycetes mushrooms: Current perspectives (Review). Int. J. Med. Mushrooms, 1, 31–62.
Yang, B.K., Kim, D.H., Jeong, S.C., Das, S., Choi, Y.S., Shin, J.S., Lee, S.C. & Song, C.H. (2002): Hypoglycaemic effect of a Lentinus edodes exopolymer produced from a submerged mycelia culture. Biosci. Biotech. Bioch., 66, 937–942.
Zhang, H.N., He, J.H., Yuan, L. & Lin, Z.B. (2003): In vitro and in vivo protective effect of Ganoderma lucidum polysacharides on alloxan-induced pancreatic islets damage. Life Sci., 73, 2307–2319.
Zhang, Y., Li, S., Wang, X., Zhang, L. & Cheung, P.C.K. (2011): Advances in lentinan: Isolation, structure, chain conformation and bioactivities. Food Hydrocolloids, 25, 196–206.