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  • 1 Department of Medicinal Chemistry, Faculty of Pharmacy, Medical University of Lublin, Jaczewskiego 4, 20-090, Lublin, Poland
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Summary

This review focuses on the salting-out effect and its use in chromatographic analysis, mainly thin-layer chromatography. First, a theoretical background is given, focusing on the general salting-out theory and a comparison with chaotropic salt addition, practised recently in reversed-phase chromatography. All the salting-out chromatographic applications in literature (from the 1960s to the present moment) are then reviewed.

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