Acta Chromatographica
Volume/Issue:
Volume 25: Issue 4
Optimization and validation of a method based on derivatization with methylating agent followed by HPLC-DAD for determining dithiocarbamates residues
Authors:
L. Zhou Department of Applied Chemistry, College of Science, China Agricultural University, Beijing, 100193, China

Search for other papers by L. Zhou in
Current site
Google Scholar
PubMed Close
,
J. Xu Department of Applied Chemistry, College of Science, China Agricultural University, Beijing, 100193, China

Search for other papers by J. Xu in
Current site
Google Scholar
PubMed Close
,
L. Luan Department of Applied Chemistry, College of Science, China Agricultural University, Beijing, 100193, China

Search for other papers by L. Luan in
Current site
Google Scholar
PubMed Close
,
J. Ma Department of Applied Chemistry, College of Science, China Agricultural University, Beijing, 100193, China

Search for other papers by J. Ma in
Current site
Google Scholar
PubMed Close
,
Y. Gong Institute for the Control of Agrochemicals, Ministry of Agriculture, Beijing, 100026, China

Search for other papers by Y. Gong in
Current site
Google Scholar
PubMed Close
,
D. Qin Institute for the Control of Agrochemicals, Ministry of Agriculture, Beijing, 100026, China

Search for other papers by D. Qin in
Current site
Google Scholar
PubMed Close
, and
C. Pan Department of Applied Chemistry, College of Science, China Agricultural University, Beijing, 100193, China

Search for other papers by C. Pan in
Current site
Google Scholar
PubMed Close
Pages:
613–625
Online Publication Date:
01 Dec 2013
Publication Date:
01 Dec 2013
Article Category:
Research Article
DOI:
https://doi.org/10.1556/achrom.25.2013.4.2
Keywords:
dithiocarbamates; methyl derivatization; pesticide residue; HPLC
Full access

Summary

Dithiocarbamates fungicides (DTCs) are worldwidely used fungicides. Residue analytical methods on DTCs are usually based on headspace gas chromatography, which are not much stable and precise. In this study, a specific, simple and reliable method for determining DTCs fungicides residues was optimized and validated. The DTCs in foods and soils were extracted with an alkaline solution of EDTA and l-cysteine, followed by pH adjusting and methyl derivatization in methyl iodine solution. The organic layer of the reactants was separated, concentrated under vacuum and reconstructed in acetonitrile. DTCs residues were eluted on a C18 column and detected by HPLC-DAD at 272 nm. The S-alkyl derivatives of thiram, mancozeb and propineb were separated at different retention times. At fortified levels of 0.05 mg/kg to 2 mg/kg (residue expressed as CS2, in mg/kg, the same below), it is found that recoveries for DTCs spiked in apple, cucumber, tomato, rice and soil samples ranged from 70.8% to 105.3%, with relative standard deviations (RSD) from 0.6% to 13.7%. Limits of detection (LODs) and quantification (LOQs) ranged from 0.003 to 0.026 mg/kg and from 0.011 to 0.105 mg/kg for various foods and soils. This method was also applied to real sample tests.

  • [1]. European Commission (EC, 2007) http://ec.europa.eu/food/fvo/specialreports/pesticide_residues/annex_2_2005_en.pdf.

  • [2]. A.K. Malik W. Faubel 1999 Pestic. Sci. 55 965.

  • [3]. O.H.J. Szolar 2007 Anal. Chim. Acta 58 191.

  • [4]. G. Crnogorac W. Schwack 2009 Trends Anal. Chem. 28 40.

  • [5]. G.E. Keppel 1965 J. Assoc. Off Anal. Chem. 52 162.

  • [6]. M.J.M. Jongen J.C. Ravensberg Ravensberg 1991 J. Chromatogr. Sci. 29 292.

  • [7]. N. Ahmad L. Guo P. Mandarakas V. Frarah S. Appleby T. Gibson 1996 J. AOAC Int. 79 1417.

  • [8]. Z. Vryzas E.N. Papadakis E. Papadopoulou-Mourkidou 2002 J. Agric. Food Chem. 50 2220.

  • [9]. W. Schwack S. Nyanzi 1995 J. AOAC Int. 78 458.

  • [10]. M. Häfner 1977 Gesunde Pflanz. 29 261.

  • [11]. H.P. Their 1977 Lebensmittelchem. Gerichtl. Chem. 31 25.

  • [12]. R.C. Perz H. Lishaut W. Schwack 2000 J. Agric. Food Chem. 48 792.

  • [13]. Joint FAO/WHO food standard programme codex committee on pesticide residues, 39th Session, Beijing, China, 2007, CX/PR 07/39/6-Add. 1.

    • Search Google Scholar
    • Export Citation

  • [14]. EU Reference Laboratories for Residues of Pesticides, 18.12.2009 (V2) http://www.eurl-pesticides.eu/docs/public/home.asp?LabID=100&Lang=EN.

    • Search Google Scholar
    • Export Citation

  • [15]. Joint FAO/WHO food standard programme codex committee on pesticide residues, 43rd Session Beijing, China, 2011, CX/PR 11/43/3.

  • [16]. K.H. Gustafsson R.A. Thompson 1981 J. Agric. Food Chem. 29 729.

  • [17]. K.H. Gustafsson C.H. Fahlgren 1983 J. Agric. Food Chem. 31 461.

  • Collapse
  • Expand
Cover Acta Chromatographica
Acta Chromatographica
Online ISSN:
2083-5736
Submit Your Manuscript

 

The author instructions are available in PDF.
Please, download the file from HERE.

 

 

Senior editors

Editor(s)-in-Chief: Kowalska, Teresa (1946-2023)

Editor(s)-in-Chief: Sajewicz, Mieczyslaw, University of Silesia, Katowice, Poland

Editors(s)

  • Danica Agbaba, University of Belgrade, Belgrade, Serbia
  • Łukasz Komsta, Medical University of Lublin, Lublin, Poland
  • Ivana Stanimirova-Daszykowska, University of Silesia, Katowice, Poland
  • Monika Waksmundzka-Hajnos, Medical University of Lublin, Lublin, Poland

Editorial Board

  • Ravi Bhushan, The Indian Institute of Technology, Roorkee, India
  • Jacek Bojarski, Jagiellonian University, Kraków, Poland
  • Bezhan Chankvetadze, State University of Tbilisi, Tbilisi, Georgia
  • Michał Daszykowski, University of Silesia, Katowice, Poland
  • Tadeusz H. Dzido, Medical University of Lublin, Lublin, Poland
  • Attila Felinger, University of Pécs, Pécs, Hungary
  • Kazimierz Glowniak, Medical University of Lublin, Lublin, Poland
  • Bronisław Glód, Siedlce University of Natural Sciences and Humanities, Siedlce, Poland
  • Anna Gumieniczek, Medical University of Lublin, Lublin, Poland
  • Urszula Hubicka, Jagiellonian University, Kraków, Poland
  • Krzysztof Kaczmarski, Rzeszow University of Technology, Rzeszów, Poland
  • Huba Kalász, Semmelweis University, Budapest, Hungary
  • Katarina Karljiković Rajić, University of Belgrade, Belgrade, Serbia
  • Imre Klebovich, Semmelweis University, Budapest, Hungary
  • Angelika Koch, Private Pharmacy, Hamburg, Germany
  • Piotr Kus, Univerity of Silesia, Katowice, Poland
  • Debby Mangelings, Free University of Brussels, Brussels, Belgium
  • Emil Mincsovics, Corvinus University of Budapest, Budapest, Hungary
  • Ágnes M. Móricz, Centre for Agricultural Research, Budapest, Hungary
  • Gertrud Morlock, Giessen University, Giessen, Germany
  • Anna Petruczynik, Medical University of Lublin, Lublin, Poland
  • Robert Skibiński, Medical University of Lublin, Lublin, Poland
  • Bernd Spangenberg, Offenburg University of Applied Sciences, Germany
  • Tomasz Tuzimski, Medical University of Lublin, Lublin, Poland
  • Yvan Vander Heyden, Free University of Brussels, Brussels, Belgium
  • Adam Voelkel, Poznań University of Technology, Poznań, Poland
  • Brata Walczak, University of Silesia, Katowice, Poland
  • Wiesław Wasiak, Adam Mickiewicz University, Poznań, Poland
  • Igor G. Zenkevich, St. Petersburg State University, St. Petersburg, Russian Federation

 

KOWALSKA, TERESA (1946-2023)
E-mail: kowalska@us.edu.pl

SAJEWICZ, MIECZYSLAW
E-mail:msajewic@us.edu.pl

Indexing and Abstracting Services:

  • Science Citation Index
  • Sci Search
  • Research Alert
  • Chemistry Citation Index and Current Content/Physical
  • Chemical and Earth Sciences
  • SCOPUS
  • GoogleScholar
  • Index Copernicus
  • CABI
  • CABELLS Journalytics

2023  
Web of Science  
Journal Impact Factor 1.7
Rank by Impact Factor Q3 (Chemistry, Analytical)
Journal Citation Indicator 0.43
Scopus  
CiteScore 4.0
CiteScore rank Q2 (General Chemistry)
SNIP 0.706
Scimago  
SJR index 0.344
SJR Q rank Q3

Acta Chromatographica
Publication Model Online only
Gold Open Access
Submission Fee none
Article Processing Charge 400 EUR/article
Regional discounts on country of the funding agency World Bank Lower-middle-income economies: 50%
World Bank Low-income economies: 100%
Further Discounts Editorial Board / Advisory Board members: 50%
Corresponding authors, affiliated to an EISZ member institution subscribing to the journal package of Akadémiai Kiadó: 100%
Subscription Information Gold Open Access
Purchase per Title  

Acta Chromatographica
Language English
Size A4
Year of
Foundation		 1988
Volumes
per Year		 1
Issues
per Year		 4
Founder Institute of Chemistry, University of Silesia
Founder's
Address		 PL-40-007 Katowice, Poland, Bankowa 12
Publisher Akadémiai Kiadó
Publisher's
Address		 H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Responsible
Publisher		 Chief Executive Officer, Akadémiai Kiadó
ISSN 2083-5736 (Online)

Monthly Content Usage

Abstract Views Full Text Views PDF Downloads
Apr 2024 0 19 5
May 2024 0 19 8
Jun 2024 0 28 4
Jul 2024 0 14 15
Aug 2024 0 23 12
Sep 2024 0 29 9
Oct 2024 0 0 0