Acta Chromatographica
Volume/Issue:
Volume 26: Issue 2
Facile assay method for norfloxacin and ciprofloxacin by sequential injection chromatography
Authors:
R. E. E. Elgorashe Department of Chemistry, College of Science, Sudan University of Science and Technology, Khartoum, Sudan

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A. M. Idris Department of Chemistry, College of Science, King Khalid University, Abha, Saudi Arabia

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M. A. Abdelrahman Department of Chemistry, College of Science, Sudan University of Science and Technology, Khartoum, Sudan
Department of Chemistry, College of Applied Health Sciences, Tarabah, Taif University, Taif, Saudi Arabia

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A. E. M. Saeed Department of Chemistry, College of Science, Sudan University of Science and Technology, Khartoum, Sudan

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Pages:
321–334
Online Publication Date:
01 Jun 2014
Publication Date:
01 Jun 2014
Article Category:
Research Article
DOI:
https://doi.org/10.1556/achrom.26.2014.2.9
Keywords:
sequential injection chromatography; norfloxacin; ciprofloxacin; method validation
Open access

Summary

Sequential injection chromatography (SIC) is a simple, inexpensive, portable, reagent-saving, and environmentally benign separation technique. This paper reports the development of a facile assay method for norfloxacin (NF) and ciprofloxacin (CF) in their formulations (tablets and eye drops) using SIC. The analytes were rapidly chromatographed on a short C18 monolithic column (4.6 × 50 mm) at a flow rate of 30 μL s−1. An isocratic mode was adopted. The optimum mobile phase composition was 90% water, 10% acetonitrile, and 0.3% triethylamine at pH 3.0. Miniaturized fiber optic spectrometric devices were coupled to the SIC system for UV detection at 280 nm. Sufficient separation with a resolution of 1.6 and numbers of theoretical plates of more than 1500 was achieved. Additionally, acceptable peak shapes with peak symmetries of 0.89 and 0.92 for NF and CF, respectively, were obtained. The method was validated and found to be reliable (the recovery was 98.0–100.6%) and precise (the RSDs of intra-/inter-day precision were less than 2.0%). The method is also sensitive. The limits of detection were less than 0.27 μg mL−1. The provided method could be considered an industrial scale since the sample frequency was seven samples h−1 and the total volume of consumed reagents was 11.5 mL.

  • [1]. A.M. Idris 2010 Crit. Rev. Anal. Chem. 40 150.

  • [2]. A.M. Idris 2010 Crit. Rev. Anal. Chem. 40 218.

  • [3]. M.A. Feres P.R. Fortes E.A.G. Zagatto J.L.M. Santos J.L.F.C. Lima 2008 Anal. Chim. Acta 618 1.

  • [4]. J. Ruzicka G.D. Marshall 1990 Anal. Chim. Acta 237 329.

  • [5]. D. Satinsky P. Solich P. Chocholous R. Karlicek 2003 Anal. Chim. Acta 499 205.

  • [6]. V. Gomez M.P. Callao 2007 TrAC, Trends Anal. Chem. 26 767.

  • [7]. A.M. Idris R.E.E. Elgorashe F.N. Assubaie A.O. Alnajjar 2011 Chromatographia 73 431.

  • [8]. A.M. Idris S.A. Naheid M.A.H. Eltayeb R.E.E. Elgorashe H.N. Al-Akra 2011 J. Liq. Chromatogr. Relat. Technol. 34 2256.

  • [9]. A.M. Idris R.E.E. Elgorashe 2011 Microchem. J. 99 174.

  • [10]. A.M. Idris R.E.E. Elgorashe 2011 Chem. Cent. J. 5 28.

  • [11]. A.M. Idris S.A. Naheid R.E.E. Elgorashe A.O. Alanajjar M.A.H. Eltayeb 2012 Anal. Method. 4 2081.

  • [12]. A.M. Idris R.E.E. Elgorashe 2012 J. AOAC Intern. 96 282.

  • [13]. A.M. Idris 2012 J. Liq. Chromatogr. Relat. Technol. 35 2884.

  • [14]. H.B. Lee T.E. Peart M.L. Svoboda 2007 J. Chromatogr. A. 1139 45.

  • [15]. J.S. Bradley M.A. Jackson M.T. Brady H.H. Bernstein C.L. Byington K.M. Edwards M.C. Fisher R.E. Willoughby 2011 Pediatrics 128 1034.

    • Search Google Scholar
    • Export Citation

  • [16]. S. Heeb M.P. Fletcher S.R. Chhabra S.P. Diggle P. Williams M. Camara 2011 Fems. Microbiol. Rev. 35 247.

  • [17]. J.F. Huang Y.Q. Feng X.H. Lin 2009 Chin. Pharm. J. 44 941.

  • [18]. J. Manceau M. Gicquel M. Laurentie P. Sanders 1999 J. Chromatogr. B 726 175.

  • [19]. L. Du H. Wei J. Zhang Q. Zhang 2003 Chin. J. Chromatogr. 21 503.

  • [20]. V.F. Samanidou C.E. Demetriou I.N. Papadoyannis 2003 Anal. Bioanal. Chem. 375 623.

  • [21]. O. Ballesteros V. Sanz-Nebot A. Navalon J.L. Vílchez J. Barbosa 2004 Chromatographia 59 543.

  • [22]. M. Ferdig A. Kaleta W. Buchberger 2005 J. Sep. Sci. 28 1448.

  • [23]. A. Espinosa-Mansilla A.M. Pena D.G. Gomez F. Salinas 2005 J. Chromatogr. B 822 185.

  • [24]. V.F. Samanidou E.A. Christodoulou I.N. Papadoyannis 2005 J. Sep. Sci. 28 2444.

  • [25]. L.A. Shervington M. Abba B. Hussain J. Donnelly 2005 J. Pharm. Biomed. Anal. 39 769.

  • [26]. S.M.B. Maia I.L. Martins D.F.D. Nascimento A.N. Cunha F.E.G. D. Lima F.A.F. Bezerra M.O. Moraes M.E.A. Moraes 2008 Ther. Drug Monit. 30 341.

    • Search Google Scholar
    • Export Citation

  • [27]. J. Sousa G. Alves A. Fortuna A. Pena C. Lino A. Falcao 2011 Biomed. Chromatogr. 25 535.

  • [28]. I.M. Choma 2003 J. Liq. Chromatogr. Relat. Technol. 26 2673.

  • [29]. J. McCourt G. Bordin A.R. Rodriguez 2003 J. Chromatogr. A. 990 259.

  • [30]. M. Ferdig A. Kaleta T.D. ThanhVo W. Buchberger 2004 J. Chromatogr. A 1047 305.

  • [31]. H. Sun P. He Y. Lv X. Zhao S. Liang 2006 Chem. J. Internet 8 5.

  • [32]. Y.M. Liu L. Mei H.Y. Yue Y.M. Shi L.J. Liu 2010 Chromatographia 72 337.

  • [33]. H. Lu X. Wu Z. Xie X. Lin L. Guo C. Yan G. Chen 2005 J. Sep. Sci. 28 2210.

  • [34]. A.A.J. Torriero E. Salinas J. Raba J.J. Silber 2006 Biosens. Bioelectron. 22 109.

  • [35]. M. Thompson S.L.R. Ellison R. Wood 2002 Pure Appl. Chem. 74 835.

  • [36]. S.A. Breda A.F. Jimenez-Kairuz R.H. Manzo M.E. Olivera 2009 Int. J. Pharm. 371 106.

  • [37]. A.M. Idris A.O. Alnajjar 2007 Acta Chromatogr. 19 97.

  • [38]. A.M. Idris 2010 J. Anal. Chem. 65 36.

  • [39]. A.M. Idris 2011 Chem. Cent. J. 5 9.

  • [40]. A.M. Idris R.E.E. Elgorashe 2011 Chem. Cent. J. 5 28.

  • [41]. A.M. Idris A.E.E. Ibrahim A.M. Abulkibash T.A. Saleh K.E.E. Ibrahim 2011 Drug Test. Anal. 6 380.

  • [42]. A.M. Idris R.E.E. Elgorashe A.O. Alnajjar 2012 J. Anal. Chem. 67 497.

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Cover Acta Chromatographica
Acta Chromatographica
Online ISSN:
2083-5736

Senior editors

Editor(s)-in-Chief: Sajewicz, Mieczyslaw, University of Silesia, Katowice, Poland

Editors(s)

  • Danica Agbaba, University of Belgrade, Belgrade, Serbia (1953-2024)
  • Łukasz Komsta, Medical University of Lublin, Lublin, Poland
  • Ivana Stanimirova-Daszykowska, University of Silesia, Katowice, Poland
  • Monika Waksmundzka-Hajnos, Medical University of Lublin, Lublin, Poland

Editorial Board

  • Ravi Bhushan, The Indian Institute of Technology, Roorkee, India
  • Jacek Bojarski, Jagiellonian University, Kraków, Poland
  • Bezhan Chankvetadze, State University of Tbilisi, Tbilisi, Georgia
  • Michał Daszykowski, University of Silesia, Katowice, Poland
  • Tadeusz H. Dzido, Medical University of Lublin, Lublin, Poland
  • Attila Felinger, University of Pécs, Pécs, Hungary
  • Kazimierz Glowniak, Medical University of Lublin, Lublin, Poland
  • Bronisław Glód, Siedlce University of Natural Sciences and Humanities, Siedlce, Poland
  • Anna Gumieniczek, Medical University of Lublin, Lublin, Poland
  • Urszula Hubicka, Jagiellonian University, Kraków, Poland
  • Krzysztof Kaczmarski, Rzeszow University of Technology, Rzeszów, Poland
  • Huba Kalász, Semmelweis University, Budapest, Hungary
  • Katarina Karljiković Rajić, University of Belgrade, Belgrade, Serbia
  • Imre Klebovich, Semmelweis University, Budapest, Hungary
  • Angelika Koch, Private Pharmacy, Hamburg, Germany
  • Piotr Kus, Univerity of Silesia, Katowice, Poland
  • Debby Mangelings, Free University of Brussels, Brussels, Belgium
  • Emil Mincsovics, Corvinus University of Budapest, Budapest, Hungary
  • Ágnes M. Móricz, Centre for Agricultural Research, Budapest, Hungary
  • Gertrud Morlock, Giessen University, Giessen, Germany
  • Anna Petruczynik, Medical University of Lublin, Lublin, Poland
  • Robert Skibiński, Medical University of Lublin, Lublin, Poland
  • Bernd Spangenberg, Offenburg University of Applied Sciences, Germany
  • Tomasz Tuzimski, Medical University of Lublin, Lublin, Poland
  • Adam Voelkel, Poznań University of Technology, Poznań, Poland
  • Beata Walczak, University of Silesia, Katowice, Poland
  • Wiesław Wasiak, Adam Mickiewicz University, Poznań, Poland
  • Igor G. Zenkevich, St. Petersburg State University, St. Petersburg, Russian Federation

 

SAJEWICZ, MIECZYSLAW
E-mail:mieczyslaw.sajewicz@us.edu.pl

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Acta Chromatographica
Language English
Size A4
Year of
Foundation		 1988
Volumes
per Year		 1
Issues
per Year		 4
Founder Institute of Chemistry, University of Silesia
Founder's
Address		 PL-40-007 Katowice, Poland, Bankowa 12
Publisher Akadémiai Kiadó
Publisher's
Address		 H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Responsible
Publisher		 Chief Executive Officer, Akadémiai Kiadó
ISSN 2083-5736 (Online)

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