Acta Chromatographica
Volume/Issue:
Volume 27: Issue 3
Isolation and Purification of Isochlorogenic Acid A from Lonicera japonica Thunb Using High-Speed Counter-Current Chromatography
Authors:
X. X. Yu Sun Yat-sen University, No. 132 East Waihuan Rd., Guangzhou Higher Education Mega Center, Guangzhou 510006, China
Guangdong Technology Research Center for Advanced Chinese Medicine, Guangzhou 510006, China

Search for other papers by X. X. Yu in
Current site
Google Scholar
PubMed Close
,
J. W. Wu Sun Yat-sen University, No. 132 East Waihuan Rd., Guangzhou Higher Education Mega Center, Guangzhou 510006, China
Guangdong Technology Research Center for Advanced Chinese Medicine, Guangzhou 510006, China

Search for other papers by J. W. Wu in
Current site
Google Scholar
PubMed Close
,
Z. K. Liang Sun Yat-sen University, No. 132 East Waihuan Rd., Guangzhou Higher Education Mega Center, Guangzhou 510006, China
Guangdong Technology Research Center for Advanced Chinese Medicine, Guangzhou 510006, China

Search for other papers by Z. K. Liang in
Current site
Google Scholar
PubMed Close
,
M. Q. Zhao Sun Yat-sen University, No. 132 East Waihuan Rd., Guangzhou Higher Education Mega Center, Guangzhou 510006, China
Guangdong Technology Research Center for Advanced Chinese Medicine, Guangzhou 510006, China

Search for other papers by M. Q. Zhao in
Current site
Google Scholar
PubMed Close
, and
X. J. Xu Sun Yat-sen University, No. 132 East Waihuan Rd., Guangzhou Higher Education Mega Center, Guangzhou 510006, China
Guangdong Technology Research Center for Advanced Chinese Medicine, Guangzhou 510006, China

Search for other papers by X. J. Xu in
Current site
Google Scholar
PubMed Close
Pages:
541–549
Online Publication Date:
Sep 2015
Publication Date:
01 Sep 2015
Article Category:
Research Article
DOI:
https://doi.org/10.1556/achrom.27.2015.3.10
Keywords:
Lonicera japonica Thunb; isochlorogenic acid A; HSCCC
Open access

A high-speed counter-current chromatography (HSCCC) method was established for the isolation and purification of isochlorogenic acid A from Lonicera japonica Thunb. The two-phase solvent system was composed of n-hexane:ethyl acetate: isopropanol:water (2:3:2:5, v/v/v/v). From 150 mg of the ethyl acetate fraction of L. japonica Thunb, 19.65 mg of isochlorogenic acid A was obtained in a one-step HSCCC separation, with a purity of 99.1%, as determined by high-performance liquid chromatography (HPLC). The structure was further identified by ultraviolet (UV), mass spectrometry (MS) and nuclear magnetic resonance (NMR).

  • [1]

    China Pharmacopoeia Committee, Pharmacopoeia of the People's Republic of China, First Division (2010 edition), China Chemical Industry Press, Beijing, China, 2009, p. 205

    • Search Google Scholar
    • Export Citation
  • [2]

    X.F. Shang , H. Pan, M.X. Li, and X.L. Miao, J. Ethnopharmacol., 138, 1 (2011)

  • [3]

    S.Y. Zhu , Value Eng., 29, 284 (2011)

  • [4]

    X. Huang , S.L. Li, P. Li, H.J. Li, X.Y. Cai, and Y. Song, Acta. Pharm. Sin., 40, 285 (2005)

  • [5]

    B.X. Xie and Z.D. Sun, Modern Food Sci. Technol., 23, 93 (2007)

  • [6]

    Y. Ito , J. Chromatogr. A, 1065, 145 (2005)

  • [7]

    X.K. OuYang , M.C. Jin, and C.H. He, Sep. Purif. Technol., 56, 319 (2007)

  • [8]

    B. He , S.Y. Yang, and Y. Zhang, Chin. Pharm. J., 47, 1280 (2012)

  • [9]

    Y.M. Li , T.Z. Wang, and Z.X. Wang, Chin. J. Chin. Mater. Med., 26, 45 (2011)

  • [10]

    R.W. Teng , Z.H. Zhou, Z.D. Wang, and C.R. Wang, Chin. J. Magn. Reson., 19, 167 (2002)

  • Collapse
  • Expand
Cover Acta Chromatographica
Acta Chromatographica
Online ISSN:
2083-5736
Submit Your Manuscript

 

The author instructions are available in PDF.
Please, download the file from HERE.

 

 

Senior editors

Editor(s)-in-Chief: Kowalska, Teresa (1946-2023)

Editor(s)-in-Chief: Sajewicz, Mieczyslaw, University of Silesia, Katowice, Poland

Editors(s)

  • Danica Agbaba, University of Belgrade, Belgrade, Serbia
  • Łukasz Komsta, Medical University of Lublin, Lublin, Poland
  • Ivana Stanimirova-Daszykowska, University of Silesia, Katowice, Poland
  • Monika Waksmundzka-Hajnos, Medical University of Lublin, Lublin, Poland

Editorial Board

  • Ravi Bhushan, The Indian Institute of Technology, Roorkee, India
  • Jacek Bojarski, Jagiellonian University, Kraków, Poland
  • Bezhan Chankvetadze, State University of Tbilisi, Tbilisi, Georgia
  • Michał Daszykowski, University of Silesia, Katowice, Poland
  • Tadeusz H. Dzido, Medical University of Lublin, Lublin, Poland
  • Attila Felinger, University of Pécs, Pécs, Hungary
  • Kazimierz Glowniak, Medical University of Lublin, Lublin, Poland
  • Bronisław Glód, Siedlce University of Natural Sciences and Humanities, Siedlce, Poland
  • Anna Gumieniczek, Medical University of Lublin, Lublin, Poland
  • Urszula Hubicka, Jagiellonian University, Kraków, Poland
  • Krzysztof Kaczmarski, Rzeszow University of Technology, Rzeszów, Poland
  • Huba Kalász, Semmelweis University, Budapest, Hungary
  • Katarina Karljiković Rajić, University of Belgrade, Belgrade, Serbia
  • Imre Klebovich, Semmelweis University, Budapest, Hungary
  • Angelika Koch, Private Pharmacy, Hamburg, Germany
  • Piotr Kus, Univerity of Silesia, Katowice, Poland
  • Debby Mangelings, Free University of Brussels, Brussels, Belgium
  • Emil Mincsovics, Corvinus University of Budapest, Budapest, Hungary
  • Ágnes M. Móricz, Centre for Agricultural Research, Budapest, Hungary
  • Gertrud Morlock, Giessen University, Giessen, Germany
  • Anna Petruczynik, Medical University of Lublin, Lublin, Poland
  • Robert Skibiński, Medical University of Lublin, Lublin, Poland
  • Bernd Spangenberg, Offenburg University of Applied Sciences, Germany
  • Tomasz Tuzimski, Medical University of Lublin, Lublin, Poland
  • Yvan Vander Heyden, Free University of Brussels, Brussels, Belgium
  • Adam Voelkel, Poznań University of Technology, Poznań, Poland
  • Brata Walczak, University of Silesia, Katowice, Poland
  • Wiesław Wasiak, Adam Mickiewicz University, Poznań, Poland
  • Igor G. Zenkevich, St. Petersburg State University, St. Petersburg, Russian Federation

 

KOWALSKA, TERESA (1946-2023)
E-mail: kowalska@us.edu.pl

SAJEWICZ, MIECZYSLAW
E-mail:msajewic@us.edu.pl

Indexing and Abstracting Services:

  • Science Citation Index
  • Sci Search
  • Research Alert
  • Chemistry Citation Index and Current Content/Physical
  • Chemical and Earth Sciences
  • SCOPUS
  • GoogleScholar
  • Index Copernicus
  • CABI
  • CABELLS Journalytics

2023  
Web of Science  
Journal Impact Factor 1.7
Rank by Impact Factor Q3 (Chemistry, Analytical)
Journal Citation Indicator 0.43
Scopus  
CiteScore 4.0
CiteScore rank Q2 (General Chemistry)
SNIP 0.706
Scimago  
SJR index 0.344
SJR Q rank Q3

Acta Chromatographica
Publication Model Online only
Gold Open Access
Submission Fee none
Article Processing Charge 400 EUR/article
Regional discounts on country of the funding agency World Bank Lower-middle-income economies: 50%
World Bank Low-income economies: 100%
Further Discounts Editorial Board / Advisory Board members: 50%
Corresponding authors, affiliated to an EISZ member institution subscribing to the journal package of Akadémiai Kiadó: 100%
Subscription Information Gold Open Access
Purchase per Title  

Acta Chromatographica
Language English
Size A4
Year of
Foundation		 1988
Volumes
per Year		 1
Issues
per Year		 4
Founder Institute of Chemistry, University of Silesia
Founder's
Address		 PL-40-007 Katowice, Poland, Bankowa 12
Publisher Akadémiai Kiadó
Publisher's
Address		 H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Responsible
Publisher		 Chief Executive Officer, Akadémiai Kiadó
ISSN 2083-5736 (Online)

Monthly Content Usage

Abstract Views Full Text Views PDF Downloads
Apr 2024 0 18 6
May 2024 0 23 3
Jun 2024 0 19 2
Jul 2024 0 15 1
Aug 2024 0 33 10
Sep 2024 0 11 0
Oct 2024 0 0 0