Acta Chromatographica
Volume/Issue:
Volume 27: Issue 4
UPLC/Q-TOF-MS Analysis for Identification of Hydrophilic Phenolics and Lipophilic Diterpenoids from Radix Salviae Miltiorrhizae
Authors:
S.T. Yang Guangdong Pharmaceutical University, Guangzhou, P.R. China

Search for other papers by S.T. Yang in
Current site
Google Scholar
PubMed Close
,
X. Wu Guangdong Pharmaceutical University, Guangzhou, P.R. China

Search for other papers by X. Wu in
Current site
Google Scholar
PubMed Close
,
W. Rui Guangdong Pharmaceutical University, Guangzhou, P.R. China

Search for other papers by W. Rui in
Current site
Google Scholar
PubMed Close
,
J. Guo Guangdong TCM Key Laboratory for Metabolic Diseases, Guangzhou, P.R. China

Search for other papers by J. Guo in
Current site
Google Scholar
PubMed Close
, and
Y.F. Feng Guangdong Pharmaceutical University, Guangzhou, P.R. China

Search for other papers by Y.F. Feng in
Current site
Google Scholar
PubMed Close
Pages:
711–728
Online Publication Date:
Dec 2015
Publication Date:
01 Dec 2015
Article Category:
Research Article
DOI:
https://doi.org/10.1556/achrom.27.2015.4.9
Keywords:
UPLC/Q-TOF-MS; phenolics; diterpenoids; fragmentation patterns; Radix; Salviae Miltiorrhizae
Open access

A rapid method has been used for simultaneous identification of both hydrophilic and lipophilic compounds from Radix Salviae Miltiorrhizae (RSM, the root of Salvia miltiorrhiza BGE.) by ultra-performance liquid chromatography/quadrupole time-offlight mass spectrometry (UPLC/Q-TOF-MS). A total of 58 compounds extracted by methanol were detected and tentatively identified within 20 min, including hydrophilic phenolics, lipophilic diterpenoids, a verbascose, and several organic acids. These compounds were separated on an Acquity UPLC BEH C18 column and identified based on tandem mass spectrometry (MS/MS) fragmentation patterns under the positive and negative ion modes, respectively. Among them, micranthin B and 9-oxo-10E,12Zoctadecadienoic acid were reported in RSM for the first time. Their fragmentation patterns in electrospray ionization (ESI)—MS/MS spectra were first investigated by matching their accurate molecular masses. This contribution presented one of the first reports on the analysis of hydrophilic phenolics and lipophilic diterpenoids from Radix Salviae Miltiorrhizae using UPLC/Q-TOF-MS. The results demonstrated that UPLC/Q-TOF-MS method could be applied to rapidly and expediently describe and provide comprehensive chemical information for simultaneous analysis of two different polar components in RSM.

  • [1]

    S.I. Jang , S.I. Jeong, K.J. Kim, et al., Planta Med., 69, 1057–1059 (1059)

  • [2]

    X. Ji , B.K. Tan, Y.C. Zhu, et al., Life Sci., 73, 1413–1426 (1426)

  • [3]

    J. Liu , H.M. Shen, and C.N. Ong, Cancer Lett., 153, 85–93 (93)

  • [4]

    S. Wasser , J.M. Ho, H.K. Ang, et al., J. Hepatol., 29, 760–771 (771)

  • [5]

    S.Y. Ryu , C.O. Lee, and S.U. Choi, Planta Med., 63, 339–342 (342)

  • [6]

    W.L. Wu , W.L. Chang, and C.F. Chen, Am. J. Chin. Med., 19, 207–216 (216)

  • [7]

    Y.G. Li , L. Song, M. Liu, et al., J. Chromatogr. A, 1216, 1941–1953 (2009)

  • [8]

    H.J. Sung , S.M. Choi, Y. Yoon, et al., Exp. Mol. Med., 31, 174–178 (178)

  • [9]

    F.N. Qu , L.W. Qi, Y.J. Wei, et al., Biol. Pharm. Bull., 31, 501–506 (506)

  • [10]

    P. Hu , G.A. Luo, Z.Z. Zhao, et al., Chem. Pharm. Bull., 53, 705–709 (709)

  • [11]

    P. Hu , G.A. Luo, Z.Z. Zhao, et al., Chem. Pharm. Bull., 53, 481–486 (486)

  • [12]

    P. Hu , Q.L. Liang, G.A. Luo, et al., Chem. Pharm. Bull., 53, 677–683 (683)

  • [13]

    G.X. Zhong , P. Li, L.J. Zeng, et al., +J. Agric. Food Chem., 57, 6879–6887 (6887)

  • [14]

    D. Guillarme , D.T. Nguyen, S. Rudaz, et al., J. Chromatogr. A, 1149, 20–29 (2007)

  • [15]

    Y. Wang , S. He, X. Cheng, et al., J. Pharm. Biomed. Anal., 80, 24–33 (33)

  • [16]

    Z.X. Liao , B.B. Zhang, L.S. Ding, et al., Acta Chromatogr., 25, 171–180 (180)

  • Collapse
  • Expand
Cover Acta Chromatographica
Acta Chromatographica
Online ISSN:
2083-5736

Senior editors

Editor(s)-in-Chief: Sajewicz, Mieczyslaw, University of Silesia, Katowice, Poland

Editors(s)

  • Danica Agbaba, University of Belgrade, Belgrade, Serbia (1953-2024)
  • Łukasz Komsta, Medical University of Lublin, Lublin, Poland
  • Ivana Stanimirova-Daszykowska, University of Silesia, Katowice, Poland
  • Monika Waksmundzka-Hajnos, Medical University of Lublin, Lublin, Poland

Editorial Board

  • Ravi Bhushan, The Indian Institute of Technology, Roorkee, India
  • Jacek Bojarski, Jagiellonian University, Kraków, Poland
  • Bezhan Chankvetadze, State University of Tbilisi, Tbilisi, Georgia
  • Michał Daszykowski, University of Silesia, Katowice, Poland
  • Tadeusz H. Dzido, Medical University of Lublin, Lublin, Poland
  • Attila Felinger, University of Pécs, Pécs, Hungary
  • Kazimierz Glowniak, Medical University of Lublin, Lublin, Poland
  • Bronisław Glód, Siedlce University of Natural Sciences and Humanities, Siedlce, Poland
  • Anna Gumieniczek, Medical University of Lublin, Lublin, Poland
  • Urszula Hubicka, Jagiellonian University, Kraków, Poland
  • Krzysztof Kaczmarski, Rzeszow University of Technology, Rzeszów, Poland
  • Huba Kalász, Semmelweis University, Budapest, Hungary
  • Katarina Karljiković Rajić, University of Belgrade, Belgrade, Serbia
  • Imre Klebovich, Semmelweis University, Budapest, Hungary
  • Angelika Koch, Private Pharmacy, Hamburg, Germany
  • Piotr Kus, Univerity of Silesia, Katowice, Poland
  • Debby Mangelings, Free University of Brussels, Brussels, Belgium
  • Emil Mincsovics, Corvinus University of Budapest, Budapest, Hungary
  • Ágnes M. Móricz, Centre for Agricultural Research, Budapest, Hungary
  • Gertrud Morlock, Giessen University, Giessen, Germany
  • Anna Petruczynik, Medical University of Lublin, Lublin, Poland
  • Robert Skibiński, Medical University of Lublin, Lublin, Poland
  • Bernd Spangenberg, Offenburg University of Applied Sciences, Germany
  • Tomasz Tuzimski, Medical University of Lublin, Lublin, Poland
  • Adam Voelkel, Poznań University of Technology, Poznań, Poland
  • Beata Walczak, University of Silesia, Katowice, Poland
  • Wiesław Wasiak, Adam Mickiewicz University, Poznań, Poland
  • Igor G. Zenkevich, St. Petersburg State University, St. Petersburg, Russian Federation

 

SAJEWICZ, MIECZYSLAW
E-mail:mieczyslaw.sajewicz@us.edu.pl

Indexing and Abstracting Services:

  • Science Citation Index
  • SCOPUS
  • DOAJ
  • Sci Search
  • Research Alert
  • Chemistry Citation Index and Current Content/Physical
  • Chemical and Earth Sciences
  • GoogleScholar
  • Index Copernicus
  • CABI
  • CABELLS Journalytics

2023  
Web of Science  
Journal Impact Factor 1.7
Rank by Impact Factor Q3 (Chemistry, Analytical)
Journal Citation Indicator 0.43
Scopus  
CiteScore 4.0
CiteScore rank Q2 (General Chemistry)
SNIP 0.706
Scimago  
SJR index 0.344
SJR Q rank Q3

Acta Chromatographica
Publication Model Online only
Gold Open Access
Submission Fee none
Article Processing Charge 700 EUR/article
Regional discounts on country of the funding agency World Bank Lower-middle-income economies: 50%
World Bank Low-income economies: 100%
Further Discounts Editorial Board / Advisory Board members: 50%
Corresponding authors, affiliated to an EISZ member institution subscribing to the journal package of Akadémiai Kiadó: 100%
Subscription Information Gold Open Access
Purchase per Title  

Acta Chromatographica
Language English
Size A4
Year of
Foundation		 1988
Volumes
per Year		 1
Issues
per Year		 4
Founder Institute of Chemistry, University of Silesia
Founder's
Address		 PL-40-007 Katowice, Poland, Bankowa 12
Publisher Akadémiai Kiadó
Publisher's
Address		 H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Responsible
Publisher		 Chief Executive Officer, Akadémiai Kiadó
ISSN 2083-5736 (Online)

Monthly Content Usage

Abstract Views Full Text Views PDF Downloads
Oct 2024 0 119 28
Nov 2024 0 91 14
Dec 2024 0 98 19
Jan 2025 0 69 26
Feb 2025 0 82 19
Mar 2025 0 110 25
Apr 2025 0 0 0