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  • 1 Department of Transplantation and Surgery, Semmelweis University, Budapest, Hungary
  • 2 Department of Neurology, Semmelweis University, Budapest, Hungary
  • 3 National Center for Epidemiology, Budapest, Hungary
  • 4 Department of Transplantation and Surgery, Semmelweis University, Baross utca 23, H-1082, Budapest, Hungary
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The complications caused by the rarely viral infections are more frequently treated in ICU (intensive care unit). The world paid attention to the WNV (West Nile virus) infections only in 1999, when 62 meningoencephalitis were registered in New York State. Six cases of WNV occur annually in Hungary. The authors present the first transplanted Hungarian patient with WNV encephalitis. The patient was hospitalized with epigastric pain, diarrhea, continuous fever, and decreasing amount of urine. The first checkup of infectious diseases was without any result. Although using of empirical antimicrobal therapy, the multiorgan failure patient remained febrile. On the basis of clinical signs, meningitis or encephalitis was suspected despite negative results of repeated cultures. On the 8th day, WNV infection was confirmed by serological examinations. With intravenous immunoglobulin therapy used within confines of supportive treatment, the patient became afebrile. After 21 days in ICU with good graft function, the patient was moved to the ward and he left the hospital after two more weeks. Until now, no prophylactic or etiological treatment has been developed for WNV. The early treatment is done with immunoglobulin or interferon; otherwise therapy has only supportive function. The disease caused by virus is more aggressive in transplanted patients and could be caused death.

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  • Medicine (miscellaneous) SJR Quartile Score (2018): Q3
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Language: English

Founded in 2008
Publication: One volume of four issues annually
Publication Programme: 2020. Vol. 12.

Publishing Model: Open Access with no author fee

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Editor(s)-in-Chief: Ágoston Szél

Vice Editor(s)-in-Chief: János Gál

Vice Editor(s)-in-Chief: Kálmán Hüttl

Vice Editor(s)-in-Chief: Béla Merkely

Chair of the Editorial Board: Balázs Hauser

Editorial Board

  • Miklós Antal (University of Debrecen, Hungary)
  • Enrico Calzia (Universitätsklinikum Ulm, Germany)
  • Zoltán Csanádi (University of Debrecen, Hungary)
  • Attila Doros (Semmelweis University, Hungary)
  • Edit Dósa (Semmelweis University, Hungary)
  • Dariusz Dudek (Jagiellonian University, Poland)
  • Susumu Eguchi (Nagasaki University, Japan)
  • László Entz (Semmelweis University, Hungary)
  • Nagy A. Habib (Imperial College London, UK)
  • Balázs Hauser (Semmelweis University, Hungary)
  • Miklós D. Kertai (Duke University, USA)
  • András Komócsi (University of Pécs, Hungary)
  • Karl-Heinz Kuck (Asklepios Klinik St. Georg, Germany)
  • Pal Maurovich-Horvat (Semmelweis University, Hungary)
  • Péter Metzger (Danube Hospital/SMZ-Ost, Austria)
  • László Miskolczi (University of Miami, USA)
  • Balázs Nemes (University of Debrecen, Hungary)
  • Attila Oláh (Petz Aladár County and Teaching Hospital, Hungary)
  • Wojciech G. Polak (Erasmus Medical Center, The Netherlands)
  • Robert Reisch (Clinic Hirslanden Zurich, Switzerland)
  • Bernhard Riedel (Vanderbilt University Medical Center, USA)
  • David Royston (Harefield Hospital, UK)
  • Thomas A. Sos (New York Presbyterian Hospital, USA)
  • Wolfgang Trubel (Privatklinik Doebling, Austria)

Semmelweis University. Institute of Human Morphology and Developmental Biology
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