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  • 1 Universitas Indonesia, Jakarta, Indonesia
  • 2 Faculty of Veterinary, Institute Pertanian Bogor, Bogor, Indonesia
Open access

Objective

This study aims to evaluate the effect of soybean milk containing a combination of anti-Streptococcus mutans IgY and chitosan to the colonization of S. mutans in the saliva and to the IgY persistency in the saliva.

Materials and Methods

Experimental malnourished Sprague-Dawley rats were fed with soybean milk that is enriched with anti-S. mutans IgY and chitosan. After 15 days of feeding, we evaluated the S. mutans in dental biofilm, in addition to the persistency level of anti-S. mutans IgY.

Results

The rats that received soybean milk supplemented with anti-S. mutans IgY had the lowest number of S. mutans colonies (p < 0.05). Anti-S. mutans IgY was detected in saliva after 15 days of feeding.

Conclusions

Soybean milk supplemented with anti-S. mutans IgY and chitosan could significantly reduce S. mutans biofilm, and the supplemented anti-S. mutans IgY persisted in these rats’ saliva following the feeding period.

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