Authors:
Mohammad Alshehri King Saud University, Riyadh, Saudi Arabia

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Abdulaziz Altalhi King Saud University, Riyadh, Saudi Arabia

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Hadi J. Alqahtani Ministry of Interior, Riyadh, Saudi Arabia

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Meteab A. Almoither Prince Sultan Military Medical City, Riyadh, Saudi Arabia

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Saad A. Alhazzani King Khalid Hospital and Prince Sultan Center, Al Kharj, Saudi Arabia

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Mohammad Maish Almohammadi Prince Sultan Military Medical City, Riyadh, Saudi Arabia

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Omar Kujan Al-Farabi College for Dentistry and Nursing, Riyadh, Saudi Arabia

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Open access

Objective

The aim was to assess the effect of scaling and root planing (SRP) with and without adjunct use of an essential-oil-basedmouthwash (EOBM) on whole salivary immunoglobulin G (IgG) levels in patients with periodontal inflammation.

Methods

Fifty patients with periodontal inflammation were included. Treatment wise, these patients were randomly divided into two groups. In group 1, patients underwent SRP and were instructed to rinse with 10 mL of an EOBM twice daily for 30 days, whereas those in group 2 underwent SRP and were instructed to rinse with 10 mL of water twice daily for 30 days. Whole saliva samples were collected at baseline and after 40 days of treatment. P-values < 0.05 were considered statistically significant.

Results

At baseline, whole salivary IgG levels were comparable among patients in groups 1 (60.5 ± 5.5 mg/dL) and 2 (57.3 ± 2.4 mg/dL). After 40 days of follow-up, there is a significant decrease in whole salivary IgG levels among patients in group 1 (7.2 ± 2.4 mg/dL) as compared to those in group 2 (26.6 ± 4.6 mg/dL) (P < 0.001).

Conclusions

SRP, when performed with adjunct use of an EOBM, is more effective in reducing whole salivary IgG levels as compared to when SRP is performed without adjunct use of an EOBM.

  • 1.

    Alshehri M , Alshail F, Aldosary M, Alamri A: Comparison of an essential-oil-based oral rinse and chlorhexidine as adjuncts to scaling and root planing in the treatment of periodontal inflammation. Interv Med Appl Sci 7, 7884 (2015)

    • Search Google Scholar
    • Export Citation
  • 2.

    Fine H , Furgang D , Lieb R, Korik I, Vincent W, Barnett L: Effects of sublethal exposure to an antiseptic mouthrinse on representative plaque bacteria. J Clin Periodontol 23, 444451 (1996)

    • Search Google Scholar
    • Export Citation
  • 3.

    Javed F , Al-Kheraif A, Al Amri D, Alshehri M, Vohra F, Al-Askar M, Malmstrom H, Romanos E: Periodontal status and whole salivary cytokine profile among smokers and never-smokers with and without prediabetes. J Periodontol 86, 890898 (2015)

    • Search Google Scholar
    • Export Citation
  • 4.

    Javed F , Ahmed B, Saeed A, Mehmood A, Bain C: Whole salivary interleukin-6 and matrix metalloproteinase-8 levels in patients with chronic periodontitis with and without prediabetes. J Periodontol 85, E130135 (2014)

    • Search Google Scholar
    • Export Citation
  • 5.

    Duncan I , Armstro Fisher S, Urbaniak J, Abramovich R, Whiting H, Page R: Transfer of immunoglobulin G across the isolated perfused human placental lobule. Reprod Fertil Dev 7, 15471550 (1995)

    • Search Google Scholar
    • Export Citation
  • 6.

    Seidel M , Schulze B, Kiess W, Vogtmann C, Borte M: Determination of secretory Iga and albumin in saliva of newborn infants. Biol Neonate 78, 186190 (2000)

    • Search Google Scholar
    • Export Citation
  • 7.

    Engström E , Georg e M, Larsson P, Lally T, Taichman S, Norhagen E: Oral and systemic immunoglobulin G-subclass antibodies to actinobacillus actinomycetemcomitans leukotoxin. Oral Microbiol Immunol 14, 104108 (1999)

    • Search Google Scholar
    • Export Citation
  • 8.

    Javed F , Sundin U, Altamash M, Klinge B, Engström E: Selfperceived oral health and salivary proteins in children with type 1 diabetes. J Oral Rehabil 36, 3944 (2009)

    • Search Google Scholar
    • Export Citation
  • 9.

    Javed F , Klingspor L, Sundin U, Altamash M, Klinge B, Engström E: Periodontal conditions, oral Candida albicans and salivary proteins in type 2 diabetic subjects with emphasis on gender. BMC Oral Health 9, 12 (2009)

    • Search Google Scholar
    • Export Citation
  • 10.

    Alshehri A , Al-Kheraif A, Aldoary M, Vohra F, Malmstrom H, Romanos E, Javed F: Self-perceived oral health and whole salivary Igg levels in habitual Gutka-chewers and non-chewers. Niger J Clin Pract (2015) [Accepted]

    • Search Google Scholar
    • Export Citation
  • 11.

    Kwok S , Clark AB , Musgrave D, Potter F, Dalton G, Day J, George A, Metcalf K, Ngeh J, Nicolson A, Owusu-Agyei P, Shekhar R, Walsh K, Warburton A, Bachmann O, Myint PK; Anglia Stroke Clinical Network Evaluation Study (ASCNES) Group: The soar stroke score predicts hospital length of stay in acute stroke: An external validation study. Int J Clin Pract 69, 659665 (2015)

    • Search Google Scholar
    • Export Citation
  • 12.

    Friedant J , Gouse M, Boehme K, Siegler E, Albright C, Monlezun J, George J, Beasley M, Martin-Schild S: A simple prediction score for developing a hospital-acquired infection after acute ischemic stroke. J Stroke Cerebrovasc Dis 24, 680686 (2015)

    • Search Google Scholar
    • Export Citation
  • 13.

    Javed F , Thafeed Alghamdi S, Mikami T, Mehmood A, Bashir Ahmed H, Samaranayake P, Tenenbaum C: Effect of glycemic control on self-perceived oral health, periodontal parameters and alveolar bone loss among patients with prediabetes. J Periodontol 85, 234241 (2014)

    • Search Google Scholar
    • Export Citation
  • 14.

    Alshehri M , Alshail F, Alqahtani H, Aloriny S, Alsharif A, Kujan O: Short-term effects of scaling and root planing with or without adjunctive use of an essential-oil-based mouthwash in the treatment of periodontal inflammation in smokers. Interv Med Appl Sci 7, 114117 (2015)

    • Search Google Scholar
    • Export Citation
  • 15.

    Tsourounakis I , Palaiologou-Gallis A, Stoute D, Maney P, Lallier E: Effect of essential oil and chlorhexidine mouthwashes on gingival fibroblast survival and migration. J Periodontol 84, 12111220 (2013)

    • Search Google Scholar
    • Export Citation
  • 16.

    Dennison K , Mere dith M, Shillitoe J, Caffesse G: The antiviral spectrum of listerine antiseptic. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 79, 442448 (1995)

    • Search Google Scholar
    • Export Citation
  • 17.

    Ouhayoun P : Pene trating the plaque biofilm: Impact of essential oil mouthwash. J Clin Periodontol 30 Suppl 5, 1012 (2003)

  • 18.

    Pan P , Barnett ML , Coelho J, Brogdon C, Finnegan B: Determination of the in situ bactericidal activity of an essential oil mouthrinse using a vital stain method. J Clin Periodontol 27, 256261 (2000)

    • Search Google Scholar
    • Export Citation
  • 19.

    Youngwanichsetha S , Phumdoung S: Factors related to prediabetes among postpartum Thai women with a history of gestational diabetes mellitus. Nurs Health Sci 15, 449453 (2013)

    • Search Google Scholar
    • Export Citation
  • 20.

    Satman I , Omer B, Tutuncu Y, Kalaca S, Gedik S, Dinccag N, Karsidag K, Genc S, Telci A, Canbaz B, Turker F, Yilmaz T, Cakir B, Tuomilehto J; TURDEP-II Study Group: Twelve-year trends in the prevalence and risk factors of diabetes and prediabetes in Turkish adults. Eur J Epidemiol 28, 169180 (2013)

    • Search Google Scholar
    • Export Citation
  • 21.

    Javed F , Ahmed HB , Mehmood A, Bain C, Romanos E: Effect of nonsurgical periodontal therapy (with or without oral doxycycline delivery) on glycemic status and clinical periodontal parameters in patients with prediabetes: A short-term longitudinal randomized case-control study. Clin Oral Investig 18, 19631968 (2014)

    • Search Google Scholar
    • Export Citation
  • 22.

    Javed F , Al-Kheraif A, Rahman I, Millan-Luongo T, Feng C, Yunker M, Malmstrom H, Romanos E: Comparison of clinical and radiographic periodontal status among habitual waterpipe smokers and cigarette smokers. J Periodontol (2015) Aug 22, doi: 10.1902/Jop.2015.150235 [Epub Ahead of Print]

    • Search Google Scholar
    • Export Citation
  • 23.

    Javed F , Al-Kheraif A, Al Amri D, Mikami T, Vohra F, Warnakulasuriya S, Romanos E: Periodontal parameters and whole salivary cytokine profiles among habitual gutka chewers and non-chewers. J Periodontol 86, 689695 (2015)

    • Search Google Scholar
    • Export Citation
  • 24.

    Javed F , Chotai M, Mehmood A, Almas K: Oral mucosal disorders associated with habitual gutka usage: A review. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 109, 857864 (2010)

    • Search Google Scholar
    • Export Citation
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2019  
Scimago
H-index
11
Scimago
Journal Rank
0,220
Scimago
Quartile Score
Medicine (miscellaneous) Q3
Scopus
Cite Score
155/133=1,2
Scopus
Cite Score Rank
General Medicine 199/529 (Q2)
Scopus
SNIP
0,343
Scopus
Cites
206
Scopus
Documents
23

 

Interventional Medicine and Applied Science
Language English
Size  
Year of
Foundation
2009
Publication
Programme
changed title
Volumes
per Year
 
Issues
per Year
 
Founder Akadémiai Kiadó
Founder's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Publisher Akadémiai Kiadó
Publisher's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Responsible
Publisher
Chief Executive Officer, Akadémiai Kiadó
ISSN 2061-1617 (Print)
ISSN 2061-5094 (Online)

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