Authors:
Dávid Ágoston Kovács University of Debrecen, Debrecen, Hungary

Search for other papers by Dávid Ágoston Kovács in
Current site
Google Scholar
PubMed
Close
,
László Szabó University of Debrecen, Debrecen, Hungary

Search for other papers by László Szabó in
Current site
Google Scholar
PubMed
Close
,
Katalin Jenei University of Debrecen, Debrecen, Hungary

Search for other papers by Katalin Jenei in
Current site
Google Scholar
PubMed
Close
,
Roland Fedor University of Debrecen, Debrecen, Hungary

Search for other papers by Roland Fedor in
Current site
Google Scholar
PubMed
Close
,
Gergely Zádori University of Debrecen, Debrecen, Hungary

Search for other papers by Gergely Zádori in
Current site
Google Scholar
PubMed
Close
,
Lajos Zsom University of Debrecen, Debrecen, Hungary

Search for other papers by Lajos Zsom in
Current site
Google Scholar
PubMed
Close
,
Krisztina Kabai University of Debrecen, Debrecen, Hungary

Search for other papers by Krisztina Kabai in
Current site
Google Scholar
PubMed
Close
,
Anita Záhonyi University of Debrecen, Debrecen, Hungary

Search for other papers by Anita Záhonyi in
Current site
Google Scholar
PubMed
Close
,
László Asztalos University of Debrecen, Debrecen, Hungary

Search for other papers by László Asztalos in
Current site
Google Scholar
PubMed
Close
, and
Balázs Nemes University of Debrecen, Debrecen, Hungary

Search for other papers by Balázs Nemes in
Current site
Google Scholar
PubMed
Close
Open access

Women with renal disease, besides many dysfunctions, face increasing infertility and high-risk pregnancy due to uremia and changes of the hormonal functions. After renal transplantation, sexual dysfunction improves, providing the possibility of successful pregnancy for women of childbearing age. However, kidney transplanted patients are high-risk pregnant patients with increased maternal and fetal risks, and the graft also may be compromised during pregnancy; most studies report on several successive deliveries due to multidisciplinary team management. In clinical practice, the graft is rarely affected during the period of gestation. Fetal development disorders are also rare although preterm delivery and intrauterine growth retardation are common. For now, several studies and clinical investigations proved that, under multidisciplinary control, kidney transplanted female patients are also possible to have safe pregnancy and successful delivery. There are conflicting data in the literature about the prevention of complications and the timing of pregnancy. Herein, we would like to present some experience of our centre. A total of 847 kidney transplantations have been performed between June 1993 and December 2013 with 163 childbearing aged females (18–45 years) in our center. We report on three kidney transplanted patients who have given birth to healthy newborns. In our practice, severe complications have not been observed.

  • 1.

    Kahan D , Ponticelli C (2001): Principles and practice of renal transplantation. Martin Dunitz, United Kingdom, pp. 721766

  • 2.

    Fuchs M , Wu D, Ebcioglu Z: Pregnancy in renal transplant recipients. Semin Perinatol 31(6), 339347 (2007)

  • 3.

    McKay B , Josephson A: Pregnancy after kidney transplantation. Clin J Am Soc Nephrol 3 Suppl 2, S117125 (2008)

  • 4.

    Rahamimov R , Ben-Haroush A, Wittenberg C, Mor E, Lustig S, Gafter U, Hod M, Bar J: Pregnancy in renal transplant recipients: long-term effect on patient and graft survival. A single-center experience. Transplantation 81(5), 660664 (2006)

    • Search Google Scholar
    • Export Citation
  • 5.

    Chu H , Liu L, Chiang J, Wang H, Lai C: Sirolimus used during pregnancy in a living related renal transplant recipient: A case report. Transplant Proc 40(7), 24462448 (2008)

    • Search Google Scholar
    • Export Citation
  • 6.

    Mark B , McCrea V, Chiang J, Wang H, Lai C: Hydronephrosis in a pregnant renal transplant patient. Transplant Proc 41(9), 39623963 (2009)

    • Search Google Scholar
    • Export Citation
  • 7.

    McKay B , Josephson A: Pregnancy in recipients of solid organs, effects on mother and child. N Engl J Med 354, 1281 (2006)

  • 8.

    Alkhunaizi A , Melamed N, Hladunewich A: Pregnancy in advanced chronic kidney disease and end-stage renal disease. Curr Opin Nephrol Hypertens 24(3), 252259 (2015)

    • Search Google Scholar
    • Export Citation
  • 9.

    Richman K , Gohh R: Pregnancy after renal transplantation: a review of registry and single-center practices and outcomes. Nephrol Dial Transplant 27(9), 34283434 (2012)

    • Search Google Scholar
    • Export Citation
  • 10.

    del Mar Colon M , Hibbard U: Obstetric considerations in the management of pregnancy in kidney transplant recipients. Adv Chronic Kidney Dis 14, 168177 (2007)

    • Search Google Scholar
    • Export Citation
  • 11.

    Umans G : Medications during pregnancy: Antihypertensives and immunosuppressives. Adv Chronic Kidney Dis 14, 191198 (2007)

  • 12.

    Podymow T , August P: Hypertension in pregnancy. Adv Chronic Kidney Dis 14, 178190 (2007)

  • 13.

    Yassaee F , Moshiri F: Pregnancy outcome in kidney transplant patients. Urol J (Tehran) 4, 1417 (2007)

  • 14.

    Kwek L , Tey V, Yang L, Kanagalingam D, Kee T: Renal and obstetric outcomes in pregnancy after kidney transplantation: twelveyear experience in a Singapore transplant center. J Obstet Gynaecol Res 41(9), 13371344 (2015)

    • Search Google Scholar
    • Export Citation
  • 15.

    Cornella C , Riboni F, Praticò L, Conca R, Fenoglio R, Lazzarich E, Surico N, Paternoster M: Pregnancy and renal transplantation: a case report of the risk of antibody induction against partner antigens. Transplant Proc 41(9), 39643966 (2009)

    • Search Google Scholar
    • Export Citation
  • 16.

    Ben Haj Hassine A , Siala H, Basly M, Harzallah K, Chibani M, Rachdi R: Pregnancy in kidney transplanted women: what are the optimal conditions for a better pregnancy outcome? Tunis Med 92(8–9), 523526 (2014)

    • Search Google Scholar
    • Export Citation
  • 17.

    McKay B , Josephson A, Armenti T, August P, Coscia A, Davis L, Davison M, Easterling T, Friedman E, Hou S, Karlix J, Lake D, Lindheimer M, Matas J, Moritz J, Riely A, Ross F, Scott R, Wagoner E, Wrenshall L, Adams L, Bumgardner L, Fine N, Goral S, Krams M, Martinez M, Tolkoff-Rubin N, Pavlakis M, Scantlebury V; Women’s Health Committee of the American Society of Transplantation: Reproduction and transplantation: Report on the AST consuses conference on reproductive issues and transplantation. Am J Transplant 5(7), 15921599 (2005)

    • Search Google Scholar
    • Export Citation
  • 18.

    Ghazizadeh S , Lessan-Pezeshki M, Khatami M, Mahdavi M, Razeghi E, SeifiS, Ahmadi F, Maziar S, Azmandian J, Abbasi M: Unwanted pregnancy among kidney transplant recipients in Iran. Transplant Proc 37(7), 30853086 (2005)

    • Search Google Scholar
    • Export Citation
  • 19.

    Taskin S , Pabuccu G, Kanmaz G, Kahraman K, Kurtay G: Perinatal outcomes of idiopathic polyhydramnios. Interv Med Appl Sci 5(1), 2125 (2013), Epub 2013 Mar 19

    • Search Google Scholar
    • Export Citation
  • 20.

    Farzadnia M , Ayatollahi H, Hasan-Zade M, Rahimi R: A comparative study of vascular cell adhesion molecule-1 and high-sensitive C-reactive protein in normal and preeclamptic pregnancies. Interv Med Appl Sci 5(1), 2630 (2013)

    • Search Google Scholar
    • Export Citation
  • 21.

    Gerlei Z , Wettstein D, Rigó J, Asztalos L, Langer M: Childbirth after organ transplantation in Hungary. Transplant Proc 43(4), 12231224 (2011)

    • Search Google Scholar
    • Export Citation
  • Collapse
  • Expand

2019  
Scimago
H-index
11
Scimago
Journal Rank
0,220
Scimago
Quartile Score
Medicine (miscellaneous) Q3
Scopus
Cite Score
155/133=1,2
Scopus
Cite Score Rank
General Medicine 199/529 (Q2)
Scopus
SNIP
0,343
Scopus
Cites
206
Scopus
Documents
23

 

Interventional Medicine and Applied Science
Language English
Size  
Year of
Foundation
2009
Publication
Programme
changed title
Volumes
per Year
 
Issues
per Year
 
Founder Akadémiai Kiadó
Founder's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Publisher Akadémiai Kiadó
Publisher's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Responsible
Publisher
Chief Executive Officer, Akadémiai Kiadó
ISSN 2061-1617 (Print)
ISSN 2061-5094 (Online)

Monthly Content Usage

Abstract Views Full Text Views PDF Downloads
Dec 2023 0 32 1
Jan 2024 0 34 3
Feb 2024 0 11 2
Mar 2024 0 10 1
Apr 2024 0 31 0
May 2024 0 10 3
Jun 2024 0 0 0