Positron emission tomography (PET) is a very powerful diagnostic technique routinely used in a variety of medical applications. This review article summarises the developments of using microreactor technology for the radiochemical synthesis of PETagents. The advantages of manufacturing these imaging drugs using microreactors are described, and a review of reactions conducted to date is outlined.
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-
1. Phelps, M. 2000 Proc. Natl. Acad. Sci. U.S.A. 97 9226–9233.
-
2. Nutt, R. 2002 Mol. Imag. Biol. 4 11–26.
-
3. Vallabhajosula, S. 2007 Semin. Nucl. Med. 37 400–419.
-
4. Mishina, M. 2008 J. Nippon Med. Sch. 75 68–76.
-
5. Knuuti, J.; Bengel, F. M. 2008 Heart 94 360–367.
-
6. Cai, L.; Lu, S.; Pike, V. W. 2008 Eur. J. Org. Chem. 2853–2873.
-
7. Elizarov, A. M. 2009 Lab Chip 9 1326–1333.
-
8. Wiles, C.; Watts, P. 2011 Chem. Commun. 47 6512–6535.
-
9. Wiles, C.; Watts, P. 2009 Fut. Med. Chem. 1593–1612.
-
10. Mason, B. P.; Price, K. E.; Steinbacher, J. L.; Bogdan, A. R.; McQuade, D. T. 2007 Chem. Rev. 107 2300–2318.
-
11. Hessel, V.; Renken., A.; Schouten., J. C.; Yoshida., J. Micro Process Engineering: A Comprehensive Handbook Volume 2: Devices, Reactions and Applications; Wiley-VCH: Germany, 2009.
-
12. Wiles, C.; Watts, P. Micro Reaction Technology in Organic Synthesis; CRC Press Inc.: Boca Raton Florida, 2011.
-
13. Ehrfeld, W.; Hessel., V.; Lowe., H. Microreactors: New Technology for Modern Chemistry; Wiley-VCH: Germany, 2000.
-
14. Glasnov, T. N. 2011 J. Flow Chem. 1 46–51.
-
15. Glasnov, T. N. 2011 J. Flow Chem. 1 90–96.
-
16. Glasnov, T. N. 2012 J. Flow Chem. 2 28–36.
-
17. Nguyen, N.-T.; Wu, Z. 2005 J. Micromech. Microeng. 15 R1–R16.
-
18. Hessel, V.; Lowe, H.; Schonfeld, F. 2005 Chem. Eng. Sci. 60 2479–2501.
-
19. Razzaq, T.; Kappe, C. O. 2010 Chem. Asian J. 5 1274–1289.
-
20. Van Den Broek, S. A. M. W.; Nieuwland, P. J.; Koch, K.; Laverman, P.; Brocken, L.; Boerman, O. C.; Rutjes, F. P. J. T. 2011 J. Labelled Compd. Radiopharm. 54 S530.
-
21. Morini, G. L. 2004 Int. J. Them. Sci. 43 631–651.
-
22. Gustafsson, T.; Gilmour, R.; Seeberger, P. H. 2008 Chem. Commun. 3022–3024.
-
23. Baumann, M.; Baxendale, I. R.; Martin, L. J.; Ley, S. V. 2009 Tetrahedron 65 6611–6625.
-
24. Chambers, R. D.; Spink, R. C. H. 1999 Chem. Commun 883–884.
-
25. Chambers, R. D.; Holling, D.; Spink, R. C. H.; Sandford, G. 2001 Lab Chip 1 132–137.
-
26. de Mas, N.; Guenther, A.; Schmidt, M. A.; Jensen, K. F. 2003 Ind. Eng. Chem. Research 42 698–707.
-
27 Elander, N.; Jones, J. R.; Lu, S. Y.; Stone-Elander, S. 2000 Chem. Soc. Rev. 29 239–249.
-
28 Stone-Elander, S.; Elander, N. 2002 J. Labelled Compd. Radiopharm. 45 715–746.
-
29 Lazarova, N.; Simeon, F. G.; Musachio, J. L.; Lu, S. Y.; Pike, V. W. 2007 J. Labelled Compd. Radiopharm. 50 463–465.
-
30 Wiles, C.; Watts, P. 2011 Beilstein J. Org. Chem. 7 1360–1371.
-
31 Lu, S.; Watts, P.; Chin, F. T.; Hong, J.; Musachio, J. L.; Briard, E.; Pike, V. W. 2004 Lab Chip 4 523–525.
-
32 Steel, C. J.; O'Brien, A. T.; Luthra, S. K.; Brady, F. 2007 J. Labelled Compd. Radiopharm. 50 308–311.
-
33 Gillies, J. M.; Prenant, C.; Chimon, G. N.; Smethurst, G. J.; Perrie, W.; Hamblett, I.; Dekker, B. A.; Zweit, J. 2006 Appl. Rad. Isot. 64 325–332.
-
34 Gillies, J. M.; Prenant, C.; Chimon, G. N.; Smethurst, G. J.; Perrie, W.; Dekker, B. A.; Zweit, J. 2006 Appl. Rad. Isot. 64 333–338.
-
35 Wester, H. J.; Schoultz, B. W.; Hultsch, C.; Henriksen, G. 2009 Eur. J. Nucl. Med. Mol. Imaging 36 653–658.
-
36 Cheng-Lee, C.; Sui, G.; Elizarov, A.; Shu, C. J.; Shin, Y. S.; Dooley, A. N.; Huang, J.; Daridon, A.; Wyatt, P.; Stout, D.; Kolb, H. C.; Witte, O. N.; Satyamurthy, N.; Heath, J. R.; Phelps, M. E.; Quake, S. R.; Tseng, H. R. 2005 Science 310 1793–1796.
-
37 Lu, S.; Pike, V. W. 2010 J. Fluorine Chem. 131 1032–1038.
-
38 Chun, J.-H.; Lu, S.; Lee, Y.-S.; Pike, V. W. 2010 J. Org. Chem. 75 3332–3338.
-
39 Lu, S.; Giamis, A. M.; Pike, V. W. 2009 Curr. Radiopharm. 2 49–55.
-
40 Jivan, S.; Ruth, T. J.; Matteo, J. C.; O'Neil, J. P. 2007 J. Labelled Compd. Radiopharm. 50 S171.
-
41 Zeng, W.; Giamis, A. M.; Matteo, J. C.; Townsend, D.; Yu, M. J. 2007 J. Labelled Compd. Radiopharm. 50 S182.
-
42 Giamis, A. M.; Price, R.; Matteo, J. C. 2008 J. Nucl. Med. 49 46P.
-
43 Pascali, G.; Nannavecchia, G.; Pitzianti, S.; Salvadori, P. A. 2011 Nucl. Med. Bio. 38 637–644.
-
44 Cleij, M. C.; Clark, J. C.; Baron, J.-C.; Aigbirhio, F. I. 2007 J. Labelled Compd. Radiopharm. 50 19–24.
-
45 Miller, P. W.; Long, N. J.; de Mello, A. J.; Vilar, R.; Audrain, H.; Bender, D.; Passchier, J.; Gee, A. 2007 Angew. Chem. Int. Ed. 46 2875–2878.
-
46 Kealey, S.; Plisson, C.; Collier, T. L.; Long, N. J.; Husbands, S. M.; Martarello, L.; Gee, A. D. 2011 Org. Biomol. Chem. 9 3313–3319.
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| Journal of Flow Chemistry | |
|---|---|
| Language | English |
| Size | A4 |
| Year of Foundation |
2011 |
| Volumes per Year |
1 |
| Issues per Year |
4 |
| Founder | Áramlásos Kémiai Tudományos Társaság |
| Founder's Address |
H-1031 Budapest, Hungary Záhony utca 7. |
| Publisher | Akadémiai Kiadó Springer Nature Switzerland AG |
| Publisher's Address |
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245. CH-6330 Cham, Switzerland Gewerbestrasse 11 |
| Responsible Publisher |
Chief Executive Officer, Akadémiai Kiadó |
| ISSN | 2062-249X (Print) |
| ISSN | 2063-0212 (Online) |
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