Authors:
Anne-Catherine BédardUniversité de Montréal, CP 6128 Station Downtown, Montréal, Québec, H3C 3J7, Canada

Search for other papers by Anne-Catherine Bédard in
Current site
Google Scholar
PubMed
Close
,
Jeffrey SantandreaUniversité de Montréal, CP 6128 Station Downtown, Montréal, Québec, H3C 3J7, Canada

Search for other papers by Jeffrey Santandrea in
Current site
Google Scholar
PubMed
Close
, and
Shawn K. CollinsUniversité de Montréal, CP 6128 Station Downtown, Montréal, Québec, H3C 3J7, Canada

Search for other papers by Shawn K. Collins in
Current site
Google Scholar
PubMed
Close
Restricted access

The continuous-flow synthesis of a series of 11- to 26-membered macrocycles via copper-catalyzed azide-alkyne cycloaddition is reported. The approach employs homogeneous catalysis to promote formation of triazole-containing macrocycles in good to excellent yields (65–90%) at relatively high concentration (30–50 mM) using a phase separation strategy.

Supplementary Materials

    • Supplementary Material
  • Collapse
  • Expand
  • Top

To see the editorial board, please visit the website of Springer Nature.

Manuscript Submission: HERE

For subscription options, please visit the website of Springer Nature.

Journal of Flow Chemistry
Language English
Size A4
Year of
Foundation
2011
Volumes
per Year
1
Issues
per Year
4
Founder Áramlásos Kémiai Tudományos Társaság
Founder's
Address
H-1031 Budapest, Hungary Záhony utca 7.
Publisher Akadémiai Kiadó
Springer Nature Switzerland AG
Publisher's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
CH-6330 Cham, Switzerland Gewerbestrasse 11
Responsible
Publisher
Chief Executive Officer, Akadémiai Kiadó
ISSN 2062-249X (Print)
ISSN 2063-0212 (Online)

Monthly Content Usage

Abstract Views Full Text Views PDF Downloads
Apr 2022 4 0 0
May 2022 10 0 0
Jun 2022 2 0 0
Jul 2022 4 0 0
Aug 2022 17 0 0
Sep 2022 6 0 0
Oct 2022 0 0 0