European Journal of Microbiology and Immunology
Volume/Issue:
Volume 4: Issue 4
Lack of association between Toxoplasma gondii infection and occupational exposure to animals
Authors: Cosme Alvarado-Esquivel 1 , Sandy Pacheco-Vega 1 , Jesús Hernández-Tinoco 3 , Diana Saldaña-Simental 1 , Luis Sánchez-Anguiano 2 , Misael Salcedo-Jáquez 1 , Agar Ramos-Nevárez 3 , Oliver Liesenfeld, José Márquez-Conde 1 , Sandra Cerrillo-Soto 3 , Lucio Martínez-Ramírez 3 , and Carlos Guido-Arreola 3
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  • 1 Juárez University of Durango State Biomedical Research Laboratory, Faculty of Medicine and Nutrition Avenida Universidad S/N 34000 Durango Mexico
  • 2 Juárez University of Durango State Institute for Scientific Research “Dr. Roberto Rivera-Damm” Avenida Universidad S/N 34000 Durango Mexico
  • 3 Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado Clínica de Medicina Familiar Predio Canoas S/N 34079 Durango Mexico
  • 4 Charité Medical School Institute for Microbiology and Hygiene, Campus Benjamin Franklin Hindenburgdamm 27 D-12203 Berlin Germany
  • 5 Roche Molecular Systems Medical and Scientific Affairs Pleasanton CA 94588 USA
DOI:
https://doi.org/10.1556/eujmi-d-14-00024
Page Count:
184–192
Publication Date:
01 Dec 2014
Online Publication Date:
16 Dec 2014
Article Category:
Research Article
Open access

The association of infection with Toxoplasma gondii and occupational exposure to animals has been scantly determined. We performed a case-control study with 200 subjects from Durango Province, Mexico, occupationally exposed to animals and 200 age- and gender-matched subjects without this occupation. Sera from all participants were analyzed for anti-T. gondii IgG and IgM antibodies using enzyme-linked immunoassays. The association of seroprevalence with sociodemographic, work, clinical, and behavioral characteristics in cases was determined.Cases and controls had similar frequencies of anti-T. gondii IgG antibodies (12/200: 6.0% and 11/200: 5.5%, respectively) (OR = 3.0; 95% CI: 0.12–73.64; P = 1.0). The frequency of sera with high (>150 IU/ml) levels of anti-T. gondii IgG antibodies was comparable among cases and controls (P = 0.61). Seroprevalence of anti-T. gondii IgM antibodies was similar in cases (4, 2.0%) than in controls (4, 2.0%) (P = 1.0). Multivariate analysis showed that seropositivity was associated with eating while working (OR = 7.14; 95% CI: 1.91–26.72; P = 0.003) and consumption of duck meat (OR = 5.43; 95% CI: 1.43–20.54; P = 0.01).No association between seropositivity to T. gondii and occupational exposure to animals was found. However, risk factors for infection found should be taken into account to reduce the exposure to T. gondii.

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Cover European Journal of Microbiology and Immunology
European Journal of Microbiology and Immunology
Online ISSN:
2062-8633
Keywords:
Toxoplasma gondii ; infection; seroprevalence; occupational exposure; animals; epidemiology; Mexico

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