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  • 1 Juárez University of Durango State, Avenida Universidad S/N, 34000 Durango, Mexico
  • 2 Juárez University of Durango State, Avenida Universidad S/N, 34000 Durango, Mexico
  • 3 Secretary of Health, Durango, Mexico
  • 4 Secretary of Health, Toma de Zacatecas 129, 34000 Durango, Mexico
  • 5 Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado, Predio Canoas S/N, 34079 Durango, Mexico
  • 6 Juárez University of Durango State, Avenida Cuauhtémoc 223, 34000 Durango, Mexico
  • 7 Charité Medical School, Hindenburgdamm 27, D-12203 Berlin, Germany

Through a cross-sectional study design, 150 women attending public health centers with a history of stillbirths were examined for anti-Toxoplasma gondii IgG and IgM antibodies in Durango City, Mexico. Bivariate and multivariate analyses were used to assess the association of T. gondii seropositivity with the characteristics of the women with stillbirth history.

Of the 150 women (mean age: 32.09 ± 9.16 years) studied, 14 (9.3%) had anti-T. gondii IgG antibodies and six (42.9%) of them were also positive for anti-T. gondii IgM antibodies. Multivariate analysis showed that T. gondii seropositivity was associated with high frequency (4–7 days a week) of eating meat (OR = 5.52; 95% CI: 1.48–20.59; P = 0.01), history of lymphadenopathy (OR = 4.52; 95% CI: 1.14–17.82; P = 0.03), and history of surgery (OR = 8.68; 95% CI: 1.04–72.15; P = 0.04).

This is the first study on the seroepidemiology of T. gondii infection in women with a history of stillbirths in Mexico. The association of T. gondii exposure with a history of surgery warrants for further research. Risk factors for T. gondii infection found in the present survey may help to design optimal educational programs to avoid T. gondii infection.

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