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Kenneth Blum PhD
Kenneth Blum PhD
Department of Psychiatry and McKnight Brain Institute, University of Florida, College of Medicine, PO Box 103424, Gainesville, Florida, 32610-3424, USA
Department of Clinical Medicine, Malibu Beach Recovery Center, Malibu Beach, CA, USA
Department of Clinical Neurology, PATH Foundation NY, New York, NY, USA
Community Mental Health Institute, Human Global Center for Clinical & Translational Science, University of Vermont, Burlington, VT, USA
Dominion Diagnostics, Inc., North Kingstown, RI, USA
Department of Personalized Medicine, IGENE, LLC, Austin, TX, USA
Department of Psychiatry, University of Vermont, College of Medicine, Burlington, VT, USA
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Department of Clinical Medicine, Malibu Beach Recovery Center, Malibu Beach, CA, USA
Department of Clinical Neurology, PATH Foundation NY, New York, NY, USA
Community Mental Health Institute, Human Global Center for Clinical & Translational Science, University of Vermont, Burlington, VT, USA
Dominion Diagnostics, Inc., North Kingstown, RI, USA
Department of Personalized Medicine, IGENE, LLC, Austin, TX, USA
Department of Psychiatry, University of Vermont, College of Medicine, Burlington, VT, USA
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Marcelo Febo
Marcelo Febo
Department of Psychiatry and McKnight Brain Institute, University of Florida, College of Medicine, PO Box 103424, Gainesville, Florida, 32610-3424, USA
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Thomas McLaughlin
Thomas McLaughlin
Center for Psychiatric Medicine, North Andover, MA, USA
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Frans J. Cronjé
Frans J. Cronjé
University of Stellenbosch, Cape Town, South Africa
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David Han
David Han
Department of Management Science and Statistics, University of Texas at San Antonio, San Antonio, Texas, USA
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Mark S. Gold
Mark S. Gold
Department of Psychiatry and McKnight Brain Institute, University of Florida, College of Medicine, PO Box 103424, Gainesville, Florida, 32610-3424, USA
Department of Clinical Medicine, Malibu Beach Recovery Center, Malibu Beach, CA, USA
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Department of Clinical Medicine, Malibu Beach Recovery Center, Malibu Beach, CA, USA
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Abstract
Background
Following the first association between the dopamine D2 receptor gene polymorphism and severe alcoholism, there has been an explosion of research reports in the psychiatric and behavioral addiction literature and neurogenetics. With this increased knowledge, the field has been rife with controversy. Moreover, with the advent of Whole Genome-Wide Studies (GWAS) and Whole Exome Sequencing (WES), along with Functional Genome Convergence, the multiple-candidate gene approach still has merit and is considered by many as the most prudent approach. However, it is the combination of these two approaches that will ultimately define real, genetic allelic relationships, in terms of both risk and etiology. Since 1996, our laboratory has coined the umbrella term Reward Deficiency Syndrome (RDS) to explain the common neurochemical and genetic mechanisms involved with both substance and non-substance, addictive behaviors.
Methods
This is a selective review of peer-reviewed papers primary listed in Pubmed and Medline.
Results
A review of the available evidence indicates the importance of dopaminergic pathways and resting-state, functional connectivity of brain reward circuits.
Discussion
Importantly, the proposal is that the real phenotype is RDS and impairments in the brain's reward cascade, either genetically or environmentally (epigenetically) induced, influence both substance and non-substance, addictive behaviors. Understanding shared common mechanisms will ultimately lead to better diagnosis, treatment and prevention of relapse. While, at this juncture, we cannot as yet state that we have “hatched the behavioral addiction egg”, we are beginning to ask the correct questions and through an intense global effort will hopefully find a way of “redeeming joy” and permitting homo sapiens live a life, free of addiction and pain.
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Dr. Zsolt Demetrovics
Institute of Psychology, ELTE Eötvös Loránd University
Address: Izabella u. 46. H-1064 Budapest, Hungary
Phone: +36-1-461-2681
E-mail: jba@ppk.elte.hu
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| 2023 | |
|---|---|
| Web of Science | |
| Journal Impact Factor | 6.6 |
| Rank by Impact Factor | Q1 (Psychiatry) |
| Journal Citation Indicator | 1.59 |
| Scopus | |
| CiteScore | 12.3 |
| CiteScore rank | Q1 (Clinical Psychology) |
| SNIP | 1.604 |
| Scimago | |
| SJR index | 2.188 |
| SJR Q rank | Q1 |
| Journal of Behavioral Addictions | |
|---|---|
| Publication Model | Gold Open Access |
| Submission Fee | none |
| Article Processing Charge | 990 EUR/article Effective from 1st Feb 2025: 1400 EUR/article |
| Regional discounts on country of the funding agency | World Bank Lower-middle-income economies: 50% World Bank Low-income economies: 100% |
| Further Discounts | Corresponding authors, affiliated to an EISZ member institution subscribing to the journal package of Akadémiai Kiadó: 100%. |
| Subscription Information | Gold Open Access |
| Journal of Behavioral Addictions | |
|---|---|
| Language | English |
| Size | A4 |
| Year of Foundation |
2011 |
| Volumes per Year |
1 |
| Issues per Year |
4 |
| Founder | Eötvös Loránd Tudományegyetem |
| Founder's Address |
H-1053 Budapest, Hungary Egyetem tér 1-3. |
| Publisher | Akadémiai Kiadó |
| Publisher's Address |
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245. |
| Responsible Publisher |
Chief Executive Officer, Akadémiai Kiadó |
| ISSN | 2062-5871 (Print) |
| ISSN | 2063-5303 (Online) |
Senior editors
Editor(s)-in-Chief: Zsolt DEMETROVICS
Assistant Editor(s):
Csilla ÁGOSTON
Dana KATZ
Associate Editors
- Stephanie ANTONS (Universitat Duisburg-Essen, Germany)
- Joel BILLIEUX (University of Lausanne, Switzerland)
- Beáta BŐTHE (University of Montreal, Canada)
- Matthias BRAND (University of Duisburg-Essen, Germany)
- Daniel KING (Flinders University, Australia)
- Gyöngyi KÖKÖNYEI (ELTE Eötvös Loránd University, Hungary)
- Ludwig KRAUS (IFT Institute for Therapy Research, Germany)
- Marc N. POTENZA (Yale University, USA)
- Hans-Jurgen RUMPF (University of Lübeck, Germany)
- Ruth J. VAN HOLST (Amsterdam UMC, The Netherlands)
Editorial Board
- Sophia ACHAB (Faculty of Medicine, University of Geneva, Switzerland)
- Alex BALDACCHINO (St Andrews University, United Kingdom)
- Judit BALÁZS (ELTE Eötvös Loránd University, Hungary)
- Maria BELLRINGER (Auckland University of Technology, Auckland, New Zealand)
- Henrietta BOWDEN-JONES (Imperial College, United Kingdom)
- Damien BREVERS (University of Luxembourg, Luxembourg)
- Julius BURKAUSKAS (Lithuanian University of Health Sciences, Lithuania)
- Gerhard BÜHRINGER (Technische Universität Dresden, Germany)
- Silvia CASALE (University of Florence, Florence, Italy)
- Luke CLARK (University of British Columbia, Vancouver, B.C., Canada)
- Jeffrey L. DEREVENSKY (McGill University, Canada)
- Geert DOM (University of Antwerp, Belgium)
- Nicki DOWLING (Deakin University, Geelong, Australia)
- Hamed EKHTIARI (University of Minnesota, United States)
- Jon ELHAI (University of Toledo, Toledo, Ohio, USA)
- Ana ESTEVEZ (University of Deusto, Spain)
- Fernando FERNANDEZ-ARANDA (Bellvitge University Hospital, Barcelona, Spain)
- Naomi FINEBERG (University of Hertfordshire, United Kingdom)
- Sally GAINSBURY (The University of Sydney, Camperdown, NSW, Australia)
- Belle GAVRIEL-FRIED (The Bob Shapell School of Social Work, Tel Aviv University, Israel)
- Biljana GJONESKA (Macedonian Academy of Sciences and Arts, Republic of North Macedonia)
- Marie GRALL-BRONNEC (University Hospital of Nantes, France)
- Jon E. GRANT (University of Minnesota, USA)
- Mark GRIFFITHS (Nottingham Trent University, United Kingdom)
- Joshua GRUBBS (University of New Mexico, Albuquerque, NM, USA)
- Anneke GOUDRIAAN (University of Amsterdam, The Netherlands)
- Susumu HIGUCHI (National Hospital Organization Kurihama Medical and Addiction Center, Japan)
- David HODGINS (University of Calgary, Canada)
- Eric HOLLANDER (Albert Einstein College of Medicine, USA)
- Zsolt HORVÁTH (Eötvös Loránd University, Hungary)
- Susana JIMÉNEZ-MURCIA (Clinical Psychology Unit, Bellvitge University Hospital, Barcelona, Spain)
- Yasser KHAZAAL (Geneva University Hospital, Switzerland)
- Orsolya KIRÁLY (Eötvös Loránd University, Hungary)
- Chih-Hung KO (Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Taiwan)
- Shane KRAUS (University of Nevada, Las Vegas, NV, USA)
- Hae Kook LEE (The Catholic University of Korea, Republic of Korea)
- Bernadette KUN (Eötvös Loránd University, Hungary)
- Katerina LUKAVSKA (Charles University, Prague, Czech Republic)
- Giovanni MARTINOTTI (‘Gabriele d’Annunzio’ University of Chieti-Pescara, Italy)
- Gemma MESTRE-BACH (Universidad Internacional de la Rioja, La Rioja, Spain)
- Astrid MÜLLER (Hannover Medical School, Germany)
- Daniel Thor OLASON (University of Iceland, Iceland)
- Ståle PALLESEN (University of Bergen, Norway)
- Afarin RAHIMI-MOVAGHAR (Teheran University of Medical Sciences, Iran)
- József RÁCZ (Hungarian Academy of Sciences, Hungary)
- Michael SCHAUB (University of Zurich, Switzerland)
- Marcantanio M. SPADA (London South Bank University, United Kingdom)
- Daniel SPRITZER (Study Group on Technological Addictions, Brazil)
- Dan J. STEIN (University of Cape Town, South Africa)
- Sherry H. STEWART (Dalhousie University, Canada)
- Attila SZABÓ (Eötvös Loránd University, Hungary)
- Hermano TAVARES (Instituto de Psiquiatria do Hospital das Clínicas da Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil)
- Wim VAN DEN BRINK (University of Amsterdam, The Netherlands)
- Alexander E. VOISKOUNSKY (Moscow State University, Russia)
- Aviv M. WEINSTEIN (Ariel University, Israel)
- Anise WU (University of Macau, Macao, China)
- Ágnes ZSILA (ELTE Eötvös Loránd University, Hungary)
Monthly Content Usage
| Abstract Views | Full Text Views | PDF Downloads | |
|---|---|---|---|
| Aug 2024 | 0 | 62 | 25 |
| Sep 2024 | 0 | 77 | 18 |
| Oct 2024 | 0 | 238 | 11 |
| Nov 2024 | 0 | 129 | 27 |
| Dec 2024 | 0 | 80 | 18 |
| Jan 2025 | 0 | 36 | 8 |
| Feb 2025 | 0 | 0 | 0 |
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