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  • 1 Semmelweis Egyetem, Általános Orvostudományi Kar II. Belgyógyászati Klinika Budapest Szentkirályi u. 46. 1088
  • 2 Magyar Tudományos Akadémia–Semmelweis Egyetem Molekuláris Medicina Kutatócsoport Budapest

A pancreas divisum a hasnyálmirigy leggyakoribb fejlődési rendellenessége, amelyhez a vezetékrendszer három fő eltérése társulhat: a klasszikus formában a fővezetékek teljesen elkülönülnek egymástól (I-es típus); a II-es típusban a dorsalis pancreasvezeték is lehet a domináns vezető; az inkomplett formában pedig (III-as típus) másodlagos csatornán keresztül kapcsolat alakulhat ki a fővezetékek között. A pancreas divisum három klinikai állapot kialakulásához vezethet: 1. akut recidíváló pancreatitis vagy 2. a dorsalis telepben jelentkező idült pancreatitis alakulhat ki, valamint 3. pancreatogen obstruktív hasi fájdalom jelentkezhet. A diagnózis felállításában jelenleg az endoszkópos retrográd cholangiopancreatographiáé a döntő szerep, de újabban a mágneses rezonancia cholangiopancreatographia az elsődlegesen választandó noninvazív módszerré lépett elő. A pancreas divisum tünetmentes formája önmagában nem igényel orvosi beavatkozást, de az enyhe visszatérő akut pancreatitises betegeket kezelni kell. A sebészi vagy az endoszkópos beavatkozások a járulékos papilla relatív szűkülete miatt kialakult obstrukció megszüntetésére irányulnak. Orv. Hetil., 2011, 152, 1764–1771.

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