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  • 1 Semmelweis Egyetem Testnevelési és Sporttudományi Kar Budapest Alkotás út 44. 1123

A testedzés komplex, az egész testet átfogó hatásrendszere miatt valamennyi szervünket érinti. A relatív maximális aerob kapacitás (VO2max) nagysága fontos lehetett az emberré fejlődés során is, hiszen a magasabb VO2max eredményesebb táplálékszerzéssel párosulhatott. Azonban úgy tűnik, hogy a magasabb VO2max ma, a XXI. században is jelentősen befolyásolhatja a túlélést, hiszen a magasabb VO2max csökkenti a szív- és keringési, bizonyos rákos és idegrendszeri megbetegedések előfordulását is. Számos vizsgálat eredménye azt sugallja, hogy az átlagnál magasabb VO2max, a fizikai fitnesz elérése, illetve megtartása az egyik leghatékonyabb eszköz a túléléshez a modern civilizált világban is. Orv. Hetil., 2013, 154, 764–768.

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  • Bramble, D. M., Lieberman, D. E.: Endurance running and the evolution of Homo. Nature, 2004, 432, 345–352.

    Lieberman D. E. , 'Endurance running and the evolution of Homo ' (2004 ) 432 Nature : 345 -352.

    • Search Google Scholar
  • Zimmer, C.: Human evolution. Faster than a hyena? Running may make humans special. Science, 2004, 306, 1283.

    Zimmer C. , 'Human evolution. Faster than a hyena? Running may make humans special ' (2004 ) 306 Science : 1283 -.

    • Search Google Scholar
  • Raichlen, D. A., Armstrong, H., Lieberman, D. E.: Calcaneus length determines running economy: implications for endurance running performance in modern humans and Neandertals. J. Hum. Evol., 2011, 60, 299–308.

    Lieberman D. E. , 'Calcaneus length determines running economy: implications for endurance running performance in modern humans and Neandertals ' (2011 ) 60 J. Hum. Evol. : 299 -308.

    • Search Google Scholar
  • Chakravarthy, M. V., Booth, F. W.: Eating, exercise, and “thrifty” genotypes: connecting the dots toward an evolutionary understanding of modern chronic diseases. J. Appl. Physiol., 2004, 96, 3–10.

    Booth F. W. , 'Eating, exercise, and “thrifty” genotypes: connecting the dots toward an evolutionary understanding of modern chronic diseases ' (2004 ) 96 J. Appl. Physiol. : 3 -10.

    • Search Google Scholar
  • Booth, F. W., Lees, S. J.: Fundamental questions about genes, inactivity, and chronic diseases. Physiol. Genomics, 2007, 28, 146–157.

    Lees S. J. , 'Fundamental questions about genes, inactivity, and chronic diseases ' (2007 ) 28 Physiol. Genomics : 146 -157.

    • Search Google Scholar
  • Williams, P. T.: Physical fitness and activity as separate heart disease risk factors: a meta-analysis. Med. Sci. Sports Exerc., 2001, 33, 754–761.

    Williams P. T. , 'Physical fitness and activity as separate heart disease risk factors: a meta-analysis ' (2001 ) 33 Med. Sci. Sports Exerc. : 754 -761.

    • Search Google Scholar
  • Andersen, L. B.: Physical activity and physical fitness as protection against premature disease or death. Scand. J. Med. Sci. Sports, 1995, 5, 318–328.

    Andersen L. B. , 'Physical activity and physical fitness as protection against premature disease or death ' (1995 ) 5 Scand. J. Med. Sci. Sports : 318 -328.

    • Search Google Scholar
  • Blair, S. N., Kohl, H. W. 3rd, Barlow, C. E., et al.: Changes in physical fitness and all-cause mortality. A prospective study of healthy and unhealthy men. JAMA, 1995, 273, 1093–1098.

    Barlow C. E. , 'Changes in physical fitness and all-cause mortality. A prospective study of healthy and unhealthy men ' (1995 ) 273 JAMA : 1093 -1098.

    • Search Google Scholar
  • Totsikas, C., Röhm, J., Kantartzis, K., et al.: Cardiorespiratory fitness determines the reduction in blood pressure and insulin resistance during lifestyle intervention. J. Hypertens., 2011, 29, 1220–1227.

    Kantartzis K. , 'Cardiorespiratory fitness determines the reduction in blood pressure and insulin resistance during lifestyle intervention ' (2011 ) 29 J. Hypertens. : 1220 -1227.

    • Search Google Scholar
  • Laukkanen, J. A., Laaksonen, D., Lakka, T. A., et al.: Determinants of cardiorespiratory fitness in men aged 42 to 60 years with and without cardiovascular disease. Am. J. Cardiol., 2009, 103, 1598–1604.

    Lakka T. A. , 'Determinants of cardiorespiratory fitness in men aged 42 to 60 years with and without cardiovascular disease ' (2009 ) 103 Am. J. Cardiol. : 1598 -1604.

    • Search Google Scholar
  • Brien, S. E., Katzmarzyk, P. T., Craig, C. L., et al.: Physical activity, cardiorespiratory fitness and body mass index as predictors of substantial weight gain and obesity: the Canadian physical activity longitudinal study. Can. J. Public Health, 2007, 98, 121–124.

    Craig C. L. , 'Physical activity, cardiorespiratory fitness and body mass index as predictors of substantial weight gain and obesity: the Canadian physical activity longitudinal study ' (2007 ) 98 Can. J. Public Health : 121 -124.

    • Search Google Scholar
  • Dvorak, R. V., Tchernof, A., Starling, R. D., et al.: Respiratory fitness, free living physical activity, and cardiovascular disease risk in older individuals: a doubly labeled water study. J. Clin. Endocrinol. Metab., 2000, 85, 957–963.

    Starling R. D. , 'Respiratory fitness, free living physical activity, and cardiovascular disease risk in older individuals: a doubly labeled water study ' (2000 ) 85 J. Clin. Endocrinol. Metab. : 957 -963.

    • Search Google Scholar
  • Hussain, S. O., Barbato, J. C., Koch, L. G., et al.: Cardiac function in rats selectively bred for low- and high-capacity running. Am. J. Physiol. Regul. Integr. Comp. Physiol., 2001, 281, R1787–R1791.

    Koch L. G. , 'Cardiac function in rats selectively bred for low- and high-capacity running ' (2001 ) 281 Am. J. Physiol. Regul. Integr. Comp. Physiol. : R1787 -R1791.

    • Search Google Scholar
  • Wisløff, U., Najjar, S. M., Ellingsen, O., et al.: Cardiovascular risk factors emerge after artificial selection for low aerobic capacity. Science, 2005, 307, 418–420.

    Ellingsen O. , 'Cardiovascular risk factors emerge after artificial selection for low aerobic capacity ' (2005 ) 307 Science : 418 -420.

    • Search Google Scholar
  • Koch, L. G., Kemi, O. J., Qi, N., et al.: Intrinsic aerobic capacity sets a divide for aging and longevity. Circ. Res., 2011, 109, 1162–1172.

    Qi N. , 'Intrinsic aerobic capacity sets a divide for aging and longevity ' (2011 ) 109 Circ. Res. : 1162 -1172.

    • Search Google Scholar
  • Koch, L. G., Britton, S. L., Wisløff, U.: A rat model system to study complex disease risks, fitness, aging, and longevity. Trends Cardiovasc. Med., 2012, 22, 29–34.

    Wisløff U. , 'A rat model system to study complex disease risks, fitness, aging, and longevity ' (2012 ) 22 Trends Cardiovasc. Med. : 29 -34.

    • Search Google Scholar
  • Hart, N., Sarga, L., Csende, Z., et al.: Resveratrol enhances exercise training responses in rats selectively bred for high running performance. Food Chem. Toxicol., 2013 Feb 17. pii: S0278-6915(13)00099-9 . doi: 10.1016/j.fct.2013.01.051 . [Epub ahead of print]

  • Atlantis, E., Chow, C. M., Kirby, A., et al.: Worksite intervention effects on physical health: a randomized controlled trial. Health Promot. Int., 2006, 21, 191–200.

    Kirby A. , 'Worksite intervention effects on physical health: a randomized controlled trial ' (2006 ) 21 Health Promot. Int. : 191 -200.

    • Search Google Scholar
  • Umar, A., Dunn, B. K., Greenwald, P.: Future directions in cancer prevention. Nat. Rev. Cancer, 2012, 12, 835–848.

    Greenwald P. , 'Future directions in cancer prevention ' (2012 ) 12 Nat. Rev. Cancer : 835 -848.

    • Search Google Scholar
  • Sawada, S. S., Muto, T., Tanaka, H., et al.: Cardiorespiratory fitness and cancer mortality in Japanese men: a prospective study. Med. Sci. Sports Exerc., 2003, 35, 1546–1550.

    Tanaka H. , 'Cardiorespiratory fitness and cancer mortality in Japanese men: a prospective study ' (2003 ) 35 Med. Sci. Sports Exerc. : 1546 -1550.

    • Search Google Scholar
  • Bernstein, L.: Exercise and breast cancer prevention. Curr. Oncol. Rep., 2009, 11, 490–496.

    Bernstein L. , 'Exercise and breast cancer prevention ' (2009 ) 11 Curr. Oncol. Rep. : 490 -496.

    • Search Google Scholar
  • Charkoudian, N., Joyner, M. J.: Physiologic considerations for exercise performance in women. Clin. Chest Med., 2004, 25, 247–255.

    Joyner M. J. , 'Physiologic considerations for exercise performance in women ' (2004 ) 25 Clin. Chest Med. : 247 -255.

    • Search Google Scholar
  • Liu, Y., Hu, F., Li, D., et al.: Does physical activity reduce the risk of prostate cancer? A systematic review and meta-analysis. Eur. Urol., 2011, 60, 1029–1044.

    Li D. , 'Does physical activity reduce the risk of prostate cancer? A systematic review and meta-analysis ' (2011 ) 60 Eur. Urol. : 1029 -1044.

    • Search Google Scholar
  • Sea, J., Poon, K. S., McVary, K. T.: Review of exercise and the risk of benign prostatic hyperplasia. Phys. Sportsmed., 2009, 37, 75–83.

    McVary K. T. , 'Review of exercise and the risk of benign prostatic hyperplasia ' (2009 ) 37 Phys. Sportsmed. : 75 -83.

    • Search Google Scholar
  • Rebillard, A., Lefeuvre-Orfila, L., Gueritat, J., et al.: Prostate cancer and physical activity: Adaptive response to oxidative stress. Free Radic. Biol. Med., 2013, 60, 115–124.

    Gueritat J. , 'Prostate cancer and physical activity: Adaptive response to oxidative stress ' (2013 ) 60 Free Radic. Biol. Med. : 115 -124.

    • Search Google Scholar
  • Antonelli, J. A., Jones, L. W., Bañez, L. L., et al.: Exercise and prostate cancer risk in a cohort of veterans undergoing prostate needle biopsy. J. Urol., 2009, 182, 2226–2231.

    Bañez L. L. , 'Exercise and prostate cancer risk in a cohort of veterans undergoing prostate needle biopsy ' (2009 ) 182 J. Urol. : 2226 -2231.

    • Search Google Scholar
  • Esser, K. A., Harpole, C. E., Prins, G. S., et al.: Physical activity reduces prostate carcinogenesis in a transgenic model. Prostate, 2009, 69, 1372–1377.

    Prins G. S. , 'Physical activity reduces prostate carcinogenesis in a transgenic model ' (2009 ) 69 Prostate : 1372 -1377.

    • Search Google Scholar
  • Radak, Z., Taylor, A. W., Sasvari, M., et al.: Telomerase activity is not altered by regular strenuous exercise in skeletal muscle or by sarcoma in liver of rats. Redox Rep., 2001, 6, 99–103.

    Sasvari M. , 'Telomerase activity is not altered by regular strenuous exercise in skeletal muscle or by sarcoma in liver of rats ' (2001 ) 6 Redox Rep. : 99 -103.

    • Search Google Scholar
  • Radak, Z., Gaal, D., Taylor, A. W., et al.: Attenuation of the development of murine solid leukemia tumor by physical exercise. Antioxid. Redox Signal., 2002, 4, 213–219.

    Taylor A. W. , 'Attenuation of the development of murine solid leukemia tumor by physical exercise ' (2002 ) 4 Antioxid. Redox Signal. : 213 -219.

    • Search Google Scholar
  • Boyle, T., Keegel, T., Bull, F., et al.: Physical activity and risks of proximal and distal colon cancers: a systematic review and meta-analysis. J. Natl. Cancer Inst., 2012, 104, 1548–1561.

    Bull F. , 'Physical activity and risks of proximal and distal colon cancers: a systematic review and meta-analysis ' (2012 ) 104 J. Natl. Cancer Inst. : 1548 -1561.

    • Search Google Scholar
  • Conney, A. H., Lou, Y. R., Nghiem, P., et al.: Inhibition of UVB-induced nonmelanoma skin cancer: a path from tea to caffeine to exercise to decreased tissue fat. Top. Curr. Chem., 2013, 329, 61–72.

    Nghiem P. , 'Inhibition of UVB-induced nonmelanoma skin cancer: a path from tea to caffeine to exercise to decreased tissue fat ' (2013 ) 329 Top. Curr. Chem. : 61 -72.

    • Search Google Scholar
  • Radak, Z., Hart, N., Sarga, L., et al.: Exercise plays a preventive role against Alzheimer’s disease. J. Alzheimers Dis., 2010, 20, 777–783.

    Sarga L. , 'Exercise plays a preventive role against Alzheimer’s disease ' (2010 ) 20 J. Alzheimers Dis. : 777 -783.

    • Search Google Scholar
  • Radak, Z., Kumagai, S., Taylor, A. W., et al.: Effects of exercise on brain function: role of free radicals. Appl. Physiol. Nutr. Metab., 2007, 32, 942–946.

    Taylor A. W. , 'Effects of exercise on brain function: role of free radicals ' (2007 ) 32 Appl. Physiol. Nutr. Metab. : 942 -946.

    • Search Google Scholar
  • Erickson, K. I., Voss, M. W., Prakash, R. S., et al.: Exercise training increases size of hippocampus and improves memory. Proc. Natl. Acad. Sci. USA, 2011, 108, 3017–3022.

    Prakash R. S. , 'Exercise training increases size of hippocampus and improves memory ' (2011 ) 108 Proc. Natl. Acad. Sci. USA : 3017 -3022.

    • Search Google Scholar
  • Fotuhi, M., Do, D., Jack, C.: Modifiable factors that alter the size of the hippocampus with ageing. Nat. Rev. Neurol., 2012, 8, 189–202.

    Jack C. , 'Modifiable factors that alter the size of the hippocampus with ageing ' (2012 ) 8 Nat. Rev. Neurol. : 189 -202.

    • Search Google Scholar
  • Rothman, S. M., Griffioen, K. J., Wan, R., et al.: Brain-derived neurotrophic factor as a regulator of systemic and brain energy metabolism and cardiovascular health. Ann. N. Y. Acad. Sci., 2012, 1264, 49–63.

    Wan R. , 'Brain-derived neurotrophic factor as a regulator of systemic and brain energy metabolism and cardiovascular health ' (2012 ) 1264 Ann. N. Y. Acad. Sci. : 49 -63.

    • Search Google Scholar
  • Madduri, S., Papaloïzos, M., Gander, B.: Synergistic effect of GDNF and NGF on axonal branching and elongation in vitro. Neurosci. Res., 2009, 65, 88–97.

    Gander B. , 'Synergistic effect of GDNF and NGF on axonal branching and elongation in vitro ' (2009 ) 65 Neurosci. Res. : 88 -97.

    • Search Google Scholar
  • Doyle, L. M., Roberts, B. L.: Exercise enhances axonal growth and functional recovery in the regenerating spinal cord. Neuroscience, 2006, 141, 321–327.

    Roberts B. L. , 'Exercise enhances axonal growth and functional recovery in the regenerating spinal cord ' (2006 ) 141 Neuroscience : 321 -327.

    • Search Google Scholar
  • Butterfield, D. A., Howard, B. J., Yatin, S., et al.: Free radical oxidation of brain proteins in accelerated senescence and its modulation by N-tert-butyl-alpha-phenylnitrone. Proc. Natl. Acad. Sci. USA, 1997, 94, 674–678.

    Yatin S. , 'Free radical oxidation of brain proteins in accelerated senescence and its modulation by N-tert-butyl-alpha-phenylnitrone ' (1997 ) 94 Proc. Natl. Acad. Sci. USA : 674 -678.

    • Search Google Scholar
  • Radak, Z., Kaneko, T., Tahara, S., et al.: Regular exercise improves cognitive function and decreases oxidative damage in rat brain. Neurochem. Int., 2001, 38, 17–23.

    Tahara S. , 'Regular exercise improves cognitive function and decreases oxidative damage in rat brain ' (2001 ) 38 Neurochem. Int. : 17 -23.

    • Search Google Scholar
  • Koltai, E., Zhao, Z., Lacza, Z., et al.: Combined exercise and insulin-like growth factor-1 supplementation induces neurogenesis in old rats, but do not attenuate age-associated DNA damage. Rejuvenation Res., 2011, 14, 585–596.

    Lacza Z. , 'Combined exercise and insulin-like growth factor-1 supplementation induces neurogenesis in old rats, but do not attenuate age-associated DNA damage ' (2011 ) 14 Rejuvenation Res. : 585 -596.

    • Search Google Scholar
  • Radak, Z., Zhao, Z., Goto, S., et al.: Age-associated neurodegeneration and oxidative damage to lipids, proteins and DNA. Mol. Aspects Med., 2011, 32, 305–315.

    Goto S. , 'Age-associated neurodegeneration and oxidative damage to lipids, proteins and DNA ' (2011 ) 32 Mol. Aspects Med. : 305 -315.

    • Search Google Scholar
  • Maesako, M., Uemura, K., Kubota, M., et al.: Exercise is more effective than diet control in preventing high fat diet-induced beta-amyloid deposition and memory deficit in amyloid precursor protein transgenic mice. J. Biol. Chem., 2012, 287, 23024–23033.

    Kubota M. , 'Exercise is more effective than diet control in preventing high fat diet-induced beta-amyloid deposition and memory deficit in amyloid precursor protein transgenic mice ' (2012 ) 287 J. Biol. Chem. : 23024 -23033.

    • Search Google Scholar
  • Tang, K., Xia, F. C., Wagner, P. D., et al.: Exercise-induced VEGF transcriptional activation in brain, lung and skeletal muscle. Respir. Physiol. Neurobiol., 2010, 170, 16–22.

    Wagner P. D. , 'Exercise-induced VEGF transcriptional activation in brain, lung and skeletal muscle ' (2010 ) 170 Respir. Physiol. Neurobiol. : 16 -22.

    • Search Google Scholar
  • Lou, S. J., Liu, J. Y., Chang, H., et al.: Hippocampal neurogenesis and gene expression depend on exercise intensity in juvenile rats. Brain Res., 2008, 1210, 48–55.

    Chang H. , 'Hippocampal neurogenesis and gene expression depend on exercise intensity in juvenile rats ' (2008 ) 1210 Brain Res. : 48 -55.

    • Search Google Scholar
  • Bullitt, E., Rahman, F. N., Smith, J. K., et al.: The effect of exercise on the cerebral vasculature of healthy aged subjects as visualized by MR angiography. AJNR Am. J. Neuroradiol., 2009, 30, 1857–1863.

    Smith J. K. , 'The effect of exercise on the cerebral vasculature of healthy aged subjects as visualized by MR angiography ' (2009 ) 30 AJNR Am. J. Neuroradiol. : 1857 -1863.

    • Search Google Scholar
  • Colcombe, S. J., Erickson, K. I., Scalf, P. E., et al.: Aerobic exercise training increases brain volume in aging humans. J. Gerontol. A. Biol. Sci. Med. Sci., 2006, 61, 1166–1170.

    Scalf P. E. , 'Aerobic exercise training increases brain volume in aging humans ' (2006 ) 61 J. Gerontol. A. Biol. Sci. Med. Sci. : 1166 -1170.

    • Search Google Scholar
  • Holzschneider, K., Wolbers, T., Röder, B., et al.: Cardiovascular fitness modulates brain activation associated with spatial learning. Neuroimage, 2012, 59, 3003–3014.

    Röder B. , 'Cardiovascular fitness modulates brain activation associated with spatial learning ' (2012 ) 59 Neuroimage : 3003 -3014.

    • Search Google Scholar
  • Radak, Z., Zhao, Z., Koltai, E., et al.: Oxygen consumption and usage during physical exercise: The balance between oxidative stress and ROS-dependent adaptive signaling. Antioxid. Redox Signal., 2013, 18, 1208–1246.

    Koltai E. , 'Oxygen consumption and usage during physical exercise: The balance between oxidative stress and ROS-dependent adaptive signaling ' (2013 ) 18 Antioxid. Redox Signal. : 1208 -1246.

    • Search Google Scholar

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