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  • 1 Ferencvárosi Egészségügyi Szolgálat KKNP Kft. Gasztroenterológia Budapest Mester u. 45. 1095
  • 2 Semmelweis Egyetem, Általános Orvostudományi Kar II. Patológiai Intézet Budapest
  • 3 Sejtdiagnosztika Kft. Budapest
  • 4 Semmelweis Egyetem, Általános Orvostudományi Kar Élettani Intézet Budapest

Bevezetés: A Helicobacter pylori prevalenciája a fejlett országokban csökken, de a jelenség időbeli lefolyása nem kellően ismert. Cél: A szerzők endoszkópos centrumukban a H. pylori-fertőzés-prevalencia időbeli változásának kiértékelését tűzték ki célul. Módszer: A szerzők 1997 és 2012 között vizsgált 4647 beteg adatait dolgozták fel. A Helicobacter pylori-fertőzést módosított Giemsa-festéssel és ureázgyorsteszttel igazolták. A fertőzés prevalenciáját az endoszkópos vizsgálat éve, a diagnózis, a születési kohorszok és a korcsoportok szerint értékelték ki. Eredmények: A fertőzés általános prevalenciája 54,7% volt: 1998-tól 71,3%-ról 2011-re 32,6%-ra csökkent. Az 1920 és 1959 közötti 10 éves születési kohorszokban a fertőzés prevalenciája 62,5% volt, 1960–1969 között 57,4%, 1970 és 1979 között 39%, 1980 és 1989 között 26,7%. A 18–19 éves korcsoportban 21,8%, 20–29 év között 34,9%, 30–39 éveseknél 46,5%, 40–49 éves korban 63,7%, 50–59 éveseknél 63,2%, 60–69 éveseknél 59,2%-os prevalenciát észleltek. A Helicobacter pylori-pozitív nyombélfekélyek aránya az 1998-as 95,9%-ról 2011-ben 59,1%-ra csökkent (p = 0,001). Következtetések: A Helicobacter pylori-fertőzés prevalenciája a vizsgált időszakban jelentősen csökkent: ez az 1960-as évek közepén, az 1970-es években született kohorszoknál kezdődött, másfél évtizeddel megelőzve a baktérium felfedezését. Orv. Hetil., 2013, 154, 900–907.

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