Bevezetés: A heveny szívizominfraktust elszenvedett betegek halálozására vonatkozó hazai adatok hiányosak. Célkitűzés: A szerzők a Magyar Infarctus Regiszterben szereplő 8582 infarktusos beteg (4981 ST-elevációval járó myocardialis infarctus) adatainak elemzésével a kórházi, a 30 napos és az egyéves halálozás vizsgálatát tűzték ki célul. Budapest öt kerületében rögzítették a prehospitális haláleseteket. Módszer: A halálozás kockázati tényezőinek vizsgálatára logisztikus regressziós analízist végeztek, majd ellenőrizték a modell illeszkedését. Eredmények: A kórházi, a 30 napos, illetve az egyéves halálozás az ST-elevációval járó infarktusos betegcsoportban 3,7%, 9,5%, illetve 16,5%, a nem ST-elevációs betegcsoportban 4%, 9,8% és 21,7% volt. A nem ST-elevációval járó infarktus miatt kezelt betegek egyéves halálozása szignifikánsan magasabb volt. A halálozás kockázati tényezőit vizsgálva az életkor, a Killip-stádium, a kórelőzményben szereplő myocardialis infarctus, stroke, valamint a diabetes bizonyult prognosztikus jelentőségűnek. A percutan coronariaintervenció mindkét típusú infarktusban nagyon jelentősen javította a betegek rövid és hosszú távú életkilátásait. Következtetések: A prehospitális halálozás igen jelentős volt, a 30 napon belül bekövetkező események 72,5%-a kórházon kívül történt. Orv. Hetil., 2013, 154, 1297–1302.
Steg, P. G., James, S. K., Atar, D., et al.: ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation. The Task Force on the management of ST-segment elevation acute myocardial infarction of the European Society of Cardiology (ESC). Eur. Heart J., 2012, 33, 2569–2619.
Atar D. , 'ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation. The Task Force on the management of ST-segment elevation acute myocardial infarction of the European Society of Cardiology (ESC) ' (2012 ) 33 Eur. Heart J. : 2569 -2619 .
Józan, P.: Change of the political system and epidemiologic transition in Hungary. [Rendszerváltozás és epidemiológiai korszakváltás Magyarországon.] Orv. Hetil., 2012, 153, 662–677. [Hungarian]
Józan P. , 'Change of the political system and epidemiologic transition in Hungary. [Rendszerváltozás és epidemiológiai korszakváltás Magyarországon.] ' (2012 ) 153 Orv. Hetil. : 662 -677 .
Józan, P.: Cardiovascular mortality (CVM) changes and their impact on epidemiological development. [A cardiovascularis mortalitás (CVM) változásának hatása az epidemiológiai fejlődésre.] Orvosképzés, 2011, 86, 91–94. [Hungarian]
Józan P. , 'Cardiovascular mortality (CVM) changes and their impact on epidemiological development. [A cardiovascularis mortalitás (CVM) változásának hatása az epidemiológiai fejlődésre.] ' (2011 ) 86 Orvosképzés : 91 -94 .
Jánosi, A., Ofner, P., Merkely, B., et al.: Myocardial Infarction Registry – 2010. Experience and first results in Hungary. [Myocardialis Infarctus Regiszter – 2010. Tapasztalatok – első eredmények.] Orv. Hetil., 2011, 152, 1278–1283. [Hungarian]
Merkely B. , 'Myocardial Infarction Registry – 2010. Experience and first results in Hungary. [Myocardialis Infarctus Regiszter – 2010. Tapasztalatok – első eredmények.] ' (2011 ) 152 Orv. Hetil. : 1278 -1283 .
Jánosi, A., Ofner, P., Voith, L.: Clinical presentation and hospital outcome of patients with ST-elevation myocardial infarction – Hungarian Myocardial Infarction Registry data. [ST-elevációval járó myocardialis infarctus miatt kezelt betegek klinikai jellemzői és kórházi prognózisa – Magyarországi Infarctus Regiszter.] Orv. Hetil., 2012, 153, 1465–1468. [Hungarian]
Voith L. , 'Clinical presentation and hospital outcome of patients with ST-elevation myocardial infarction – Hungarian Myocardial Infarction Registry data. [ST-elevációval járó myocardialis infarctus miatt kezelt betegek klinikai jellemzői és kórházi prognózisa – Magyarországi Infarctus Regiszter.] ' (2012 ) 153 Orv. Hetil. : 1465 -1468 .
Thygesen, K., Alpert, J. S., White, H. D., on behalf of the Joint ESC/ACC/AHA/WHF Task Force for the Redefinition of Myocardial Infarction: Universal Definition of Myocardial Infarction. J. Am. Coll. Cardiol., 2007, 50, 2173–2195.
White H. D. , 'Universal Definition of Myocardial Infarction ' (2007 ) 50 J. Am. Coll. Cardiol. : 2173 -2195 .
Hosmer, D. W., Lemeshow, S.: Applied logistic regression (2nd edition). John Wiley & Sons, New York, 2000.
Lemeshow S. , '', in Applied logistic regression , (2000 ) -.
Tunstall-Pedoe, H., Kuulasmaa, K., Mähönen, M., et al.: Contribution of trends in survival and coronary-event rates to changes in coronary heart disease mortality: 10-year results from 37 WHO MONICA project populations. Monitoring trends and determinants in cardiovascular disease. Lancet, 1999, 353, 1547–1557.
Mähönen M. , 'Contribution of trends in survival and coronary-event rates to changes in coronary heart disease mortality: 10-year results from 37 WHO MONICA project populations. Monitoring trends and determinants in cardiovascular disease ' (1999 ) 353 Lancet : 1547 -1557 .
Hannan, E. L., Cozzens, K., King, S. B. 3rd, et al.: The New York State cardiac registries: history, contributions, limitations, and lessons for future efforts to assess and publicly report healthcare outcomes. J. Am. Coll. Cardiol., 2012, 59, 2309–2316.
King S. B. , 'The New York State cardiac registries: history, contributions, limitations, and lessons for future efforts to assess and publicly report healthcare outcomes ' (2012 ) 59 J. Am. Coll. Cardiol. : 2309 -2316 .
Belicza, E., Jánosi, A.: Study of incidence and treatment of acute myocardial infarction by evaluating the financing database 2004–2009. [A heveny szívinfarktus előfordulásának és ellátásának vizsgálata a finanszírozási adatbázis elemzésével: 2004–2009.] Orv. Hetil., 2012, 153, 102–112. [Hungarian]
Jánosi A. , 'Study of incidence and treatment of acute myocardial infarction by evaluating the financing database 2004–2009. [A heveny szívinfarktus előfordulásának és ellátásának vizsgálata a finanszírozási adatbázis elemzésével: 2004–2009.] ' (2012 ) 153 Orv. Hetil. : 102 -112 .
Turin, T. C., Kita, Y., Rumana, N., et al.: Registration and surveillance of acute myocardial infarction in Japan: monitoring an entire community by Takashima AMI Registry: System and Design. Circ. J., 2007, 71, 1617–1621.
Rumana N. , 'Registration and surveillance of acute myocardial infarction in Japan: monitoring an entire community by Takashima AMI Registry: System and Design ' (2007 ) 71 Circ. J. : 1617 -1621 .
Fox, K. A., Eagle, K. A., Gore, J. M., et al.: The Global Registry of Acute Coronary Events, 1999 to 2009 – GRACE. Heart, 2010, 96, 1095–1101.
Gore J. M. , 'The Global Registry of Acute Coronary Events, 1999 to 2009 – GRACE ' (2010 ) 96 Heart : 1095 -1101 .
Jernberg, T., Attebring, M. F., Hambraeus, K., et al.: The Swedish web-system for enhancement and development of evidence-based care in heart disease evaluated according to recommended therapies (SWEDEHEART). Heart, 2010, 96, 1617–1621.
Hambraeus K. , 'The Swedish web-system for enhancement and development of evidence-based care in heart disease evaluated according to recommended therapies (SWEDEHEART) ' (2010 ) 96 Heart : 1617 -1621 .
Peterson, E. D., Roe, M. T., Chen, A. Y., et al.: The NCDR ACTION Registry–GWTG: transforming contemporary acute myocardial infarction clinical care. Heart, 2010, 96, 1798–1802.
Chen A. Y. , 'The NCDR ACTION Registry–GWTG: transforming contemporary acute myocardial infarction clinical care ' (2010 ) 96 Heart : 1798 -1802 .
Radovanovic, D., Erne, P.: AMIS Plus: Swiss registry of acute coronary syndrome. Heart, 2010, 96, 917–921.
Erne P. , 'AMIS Plus: Swiss registry of acute coronary syndrome ' (2010 ) 96 Heart : 917 -921 .
Mohanan, P. P., Mathew, R., Harikrishnan, S. J., et al.: Presentation, management, and outcomes of 25 748 acute coronary syndrome admissions in Kerala, India: results from the Kerala ACS Registry. Eur. Heart J., 2013, 34, 121–129.
Harikrishnan S. J. , 'Presentation, management, and outcomes of 25 748 acute coronary syndrome admissions in Kerala, India: results from the Kerala ACS Registry ' (2013 ) 34 Eur. Heart J. : 121 -129 .
Zahn, R., Schiele, R., Schneider, S., et al.: Primary angioplasty versus no reperfusion therapy in patients with acute myocardial infarction and a pre-hospital delay of >12-24 hours: results from the pooled data of the maximal individual therapy in acute myocardial infarction (MITRA) registry and the myocardial infarction registry (MIR). J. Invasive Cardiol., 2001, 13 (5), 367–372.
Schneider S. , 'Primary angioplasty versus no reperfusion therapy in patients with acute myocardial infarction and a pre-hospital delay of >12-24 hours: results from the pooled data of the maximal individual therapy in acute myocardial infarction (MITRA) registry and the myocardial infarction registry (MIR) ' (2001 ) 13 J. Invasive Cardiol. : 367 -372 .
Kim, C. S., Choi, J. S., Bae, E. H., et al.: Association of metabolic syndrome and renal insufficiency with clinical outcome in acute myocardial infarction. Metabolism, 2013, 62, 669–676.
Bae E. H. , 'Association of metabolic syndrome and renal insufficiency with clinical outcome in acute myocardial infarction ' (2013 ) 62 Metabolism : 669 -676 .
Kalla, K., Christ, G., Karnik, R., et al.: Implementation of guidelines improves the standard of care: the Viennese registry on reperfusion strategies in ST-elevation myocardial infarction (Vienna STEMI registry). Circulation, 2006, 113, 2398–2405.
Karnik R. , 'Implementation of guidelines improves the standard of care: the Viennese registry on reperfusion strategies in ST-elevation myocardial infarction (Vienna STEMI registry) ' (2006 ) 113 Circulation : 2398 -2405 .
Herrett, E., Smeeth, L., Walker, L., et al.: The Myocardial Ischaemia National Audit Project (MINAP). Heart, 2010, 96, 1264–1267.
Walker L. , 'The Myocardial Ischaemia National Audit Project (MINAP) ' (2010 ) 96 Heart : 1264 -1267 .
Dziewierz, A., Siudak, Z., Dykla, D., et al.: Management and mortality in patients with non-ST-segment elevation vs. ST segment elevation myocardial infarction. Data from the Malopolska Registry of Acute Coronary Syndromes. Kardiol. Pol., 2009, 67, 115–120.
Dykla D. , 'Management and mortality in patients with non-ST-segment elevation vs. ST segment elevation myocardial infarction. Data from the Malopolska Registry of Acute Coronary Syndromes ' (2009 ) 67 Kardiol. Pol. : 115 -120 .
Steg, P. G., Greenlaw, N., Tardif, J. C., et al.: Women and men with stable coronary artery disease have similar clinical outcomes: insights from the international prospective CLARIFY registry. Eur. Heart J., 2012, 33, 2831–2840.
Tardif J. C. , 'Women and men with stable coronary artery disease have similar clinical outcomes: insights from the international prospective CLARIFY registry ' (2012 ) 33 Eur. Heart J. : 2831 -2840 .
Widimsky, P., Wijns, W., Fajedet, J., et al.: Reperfusion therapy for ST elevation acute myocardial infarction in Europe: description of the current situation in 30 countries. Eur. Heart J., 2010, 31, 943–957.
Fajedet J. , 'Reperfusion therapy for ST elevation acute myocardial infarction in Europe: description of the current situation in 30 countries ' (2010 ) 31 Eur. Heart J. : 943 -957 .
Cambou, J. P., Simon, T., Mulak, G., et al.: The French registry of Acute ST elevation or non-ST-elevation myocardial infarction (FAST-MI): study design and baseline characteristics. Arch. Mal. Coeur Vaiss., 2007, 100, 524–534.
Mulak G. , 'The French registry of Acute ST elevation or non-ST-elevation myocardial infarction (FAST-MI): study design and baseline characteristics ' (2007 ) 100 Arch. Mal. Coeur Vaiss. : 524 -534 .
Smolina, K., Wright, F. L., Rayner, M., et al.: Incidence and 30-day case fatality for acute myocardial infarction in England in 2010: national-linked database study. Eur. J. Public Health, 2012, 22, 848–853.
Rayner M. , 'Incidence and 30-day case fatality for acute myocardial infarction in England in 2010: national-linked database study ' (2012 ) 22 Eur. J. Public Health : 848 -853 .
Jernberg, T., Johanson, P., Held, C., et al.: Association between adoption of evidence-based treatment and survival for patients with ST-elevation myocardial infarction. JAMA, 2011, 305, 1677–1684.
Held C. , 'Association between adoption of evidence-based treatment and survival for patients with ST-elevation myocardial infarction ' (2011 ) 305 JAMA : 1677 -1684 .
Montalescot, G., Dallongeville, J., Van Belle, E., et al.: STEMI and NSTEMI: are they so different? 1 year outcomes in acute myocardial infarction as defined by the ESC/ACC definition (the OPERA registry). Eur. Heart J., 2007, 28, 1409–1417.
Belle E. , 'STEMI and NSTEMI: are they so different? 1 year outcomes in acute myocardial infarction as defined by the ESC/ACC definition (the OPERA registry) ' (2007 ) 28 Eur. Heart J. : 1409 -1417 .
McManus, D. D., Gore, J., Yarzebski, J., et al.: Recent trends in the incidence, treatment, and outcomes of patients with STEMI and NSTEMI. Am. J. Med., 2011, 124, 40–47.
Yarzebski J. , 'Recent trends in the incidence, treatment, and outcomes of patients with STEMI and NSTEMI ' (2011 ) 124 Am. J. Med. : 40 -47 .
Roe, M. T., Chen, A. Y., Thomas, L., et al.: Predicting long-term mortality in older patients after non-ST-segment elevation myocardial infarction: the CRUSADE long-term mortality model and risk score. Am. Heart J., 2011, 162, 875–883.
Thomas L. , 'Predicting long-term mortality in older patients after non-ST-segment elevation myocardial infarction: the CRUSADE long-term mortality model and risk score ' (2011 ) 162 Am. Heart J. : 875 -883 .
Bramlage, P., Messer, C., Bitterlich, N., et al.: The effect of optimal medical therapy on 1-year mortality after acute myocardial infarction. Heart, 2010, 96, 604–609.
Bitterlich N. , 'The effect of optimal medical therapy on 1-year mortality after acute myocardial infarction ' (2010 ) 96 Heart : 604 -609 .
Canto, J. G., Kiefe, C. I., Rogers, W. J., et al.: Atherosclerotic risk factors and their association with hospital mortality among patients with first myocardial infarction (from the National Registry of Myocardial Infarction). Am. J. Cardiol., 2012, 110, 1256–1261.
Rogers W. J. , 'Atherosclerotic risk factors and their association with hospital mortality among patients with first myocardial infarction (from the National Registry of Myocardial Infarction) ' (2012 ) 110 Am. J. Cardiol. : 1256 -1261 .
Chambless, L., Keil, U., Dobson, A., et al.: Population versus clinical view of case fatality from acute coronary heart disease: results from the WHO MONICA Project 1985–1990. Multinational monitoring of trends and determinants in cardiovascular disease. Circulation, 1997, 96, 3849–3859.
Dobson A. , 'Population versus clinical view of case fatality from acute coronary heart disease: results from the WHO MONICA Project 1985–1990. Multinational monitoring of trends and determinants in cardiovascular disease ' (1997 ) 96 Circulation : 3849 -3859 .