A hypertonia hazánkban is az egyik leggyakoribb krónikus betegség és az egyik legfontosabb cardiovascularis kockázati tényező. A vérnyomás célértékre történő kezelésével jelentősen csökkenthető a coronariabetegség, a stroke, a krónikus vesebetegség kialakulásának a kockázata, illetve a mortalitás. A vérnyomáskontroll különösen a nagy kockázatú betegségekben játszik alapvető szerepet. A hypertonia kezelésében az életmódkezelésen kívül a gyógyszeres terápia játszik meghatározó szerepet. A gyógyszer választásánál fontos, hogy a választott antihipertenzívum-kombináció – igazolt hatása mellett – metabolikusan semleges legyen és cardiovascularis protektív hatással is rendelkezzen. A ramipril/amlodipin fix kombináció e szempontoknak megfelel, és mindezeken túlmenően a betegadherencia szempontjából is kedvező. Orv. Hetil., 2013, 154, 1658–1664.
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