JPC - Journal of Planar Chromatography - Modern TLC
Volume/Issue:
Volume 18: Issue 101
Densitometric determination of desloratadine in tablets, and validation of the method
Authors:
Endang SumarlikBernofarm Pharmaceutical Company QC Laboratory Buduran, Sidoarjo, Surabaya 61252 Indonesia

Search for other papers by Endang Sumarlik in
Current site
Google Scholar
PubMedClose
,
Hoshi TampubolonBernofarm Pharmaceutical Company QC Laboratory Buduran, Sidoarjo, Surabaya 61252 Indonesia

Search for other papers by Hoshi Tampubolon in
Current site
Google Scholar
PubMedClose
,
Mochammad YuwonoAirlangga University Assessment Service Unit, Faculty of Pharmacy Jl. Dharmawangsa dalam Surabaya 60286 Indonesia

Search for other papers by Mochammad Yuwono in
Current site
Google Scholar
PubMedClose
, and
Gunawan IndrayantoAirlangga University Assessment Service Unit, Faculty of Pharmacy Jl. Dharmawangsa dalam Surabaya 60286 Indonesia

Search for other papers by Gunawan Indrayanto in
Current site
Google Scholar
PubMedClose
View More View Less
Pages:
19–22
Online Publication Date:
13 Mar 2007
Publication Date:
01 Feb 2005
Article Category:
Research Article
DOI:
https://doi.org/10.1556/jpc.18.2005.1.3
Keywords:
TLC; Densitometry; Tablet; Validation; Desloratadine
Restricted access

A simple and rapid densitometric method has been developed for determination of desloratadine in tablets. After extraction of the samples with 96% ethanol the solutions were spotted on precoated silica gel TLC plates and these were eluted with ethyl acetate- n -butanol-25% aqueous ammonia-methanol, 21 + 5.0 + 4.0 + 5.0 ( v/v ), as mobile phase. Quantitative evaluation was performed by measuring the absorbance reflectance of the desloratadine spots at λ = 279 nm. The TLC-densitometric method is selective, precise, and accurate and can be used for routine analysis of tablets in pharmaceutical industry quality control laboratories.

  • www.fda.gov/cder/foi/label/2002/21165slr0011bl.pdf (March 31, 2004).

  • K. Parfitt , Martindale, The Complete Drug Reference, 32nd edn, Pharmaceutical Press, London, 1999, p. 413.

    Parfitt K. , '', in Martindale, The Complete Drug Reference , (1999 ) -.

  • The United States Pharmacopeia 26 — National Formulary 21, Asian edn, United States Pharmacopeial Convention, Rockville, MD, 2002.

  • British Pharmacopoeia 2002, The Stationary Office, London, 2002.

  • The International Pharmacopoeia, 3rd edn, Vol. 5, World Health Organization, Geneva, 2003.

  • L.Qi.M. Liu and P.Li.H. Wang , J. Pharm. Biomed. Anal. 34 (2004) 1013–1019.

    Wang P.Li.H. , '' (2004 ) 34 J. Pharm. Biomed. Anal. : 1013 -1019 .

  • F.Y. Zhang, X.Y. Chen, D.F. Zhong , and Y.M. Dong , Acta Pharm. Sin. 24 (2003) 715–718.

    Dong Y.M. , '' (2003 ) 24 Acta Pharm. Sin. : 715 -718 .

  • L. Yang, R.P. Clement, B. Reyderman, F. Beaudry, C. Grandmaison, L. Di Donato, R. Masse , and P.J. Rudewic , J. Chromatogr. B. Anal. Technol. Life Sci. 792 (2003) 229–240.

    Rudewic P.J. , '' (2003 ) 792 J. Chromatogr. B. Anal. Technol. Life Sci. : 229 -240 .

  • Camag Bibliography Service, Cumulative CD version 1.09, Camag, Muttenz, 2003.

  • G. Indrayanto, L. Darmawan , and S. Widjaja , J. Planar Chromatogr. 12 (1999) 261–264.

    Widjaja S. , '' (1999 ) 12 J. Planar Chromatogr. : 261 -264 .

  • Farmakope Indonesia, Edisi IV (Indonesian Pharmacopoeia, 4th edn), Departemen Kesehatan Republik Indonesia, Jakarta, 1995, pp. 999–1001.

  • W. Funk, V. Damman , and G. Donnervert , Qualitätssicherung in der Analytischen Chemie, VCH, Weinheim, 1992, pp. 12–36, 161–180.

    Donnervert G. , '', in Qualitätssicherung in der Analytischen Chemie , (1992 ) -.

  • E. Hahn-Dienstrop , Applied Thin Layer Chromatography, Wiley-VCH, Weinheim, 2000, pp. 198–205.

    Hahn-Dienstrop E. , '', in Applied Thin Layer Chromatography , (2000 ) -.

  • S. Kromidas , Validierung in der Analytik, Wiley-VCH, Weinheim, 1999, pp. 56–85, 110–113.

    Kromidas S. , '', in Validierung in der Analytik , (1999 ) -.

  • K. Ferenci-Fodor, Z. Végh , and A. Nagy-Turák , JAOAC Int. 84 (2001) 1265–1276.

    Nagy-Turák A. , '' (2001 ) 84 JAOAC Int. : 1265 -1276 .

  • G. Indrayanto and M. Yuwono , In: J. Cazes (Ed.) Encyclopedia of Chromatography — Online ( www.Dekker.com ), Marcel Dekker, New York, 2003.

    Yuwono M. , '', in Encyclopedia of Chromatography — Online , (2003 ) -.

  • G.P. Carr and J.C. Wahlich , J. Pharm. Biomed. Anal. 8 (1990) 613–618.

    Wahlich J.C. , '' (1990 ) 8 J. Pharm. Biomed. Anal. : 613 -618 .

  • J. Ermer , J. Pharm. Biomed. Anal. 24 (2001) 755–767.

    Ermer J. , '' (2001 ) 24 J. Pharm. Biomed. Anal. : 755 -767 .
  • Collapse
  • Expand
Cover JPC - Journal of Planar Chromatography - Modern TLC
JPC - Journal of Planar Chromatography - Modern TLC
Print ISSN:
0933-4173
Online ISSN:
1789-0993

To see the editorial board, please visit the website of Springer Nature.

Manuscript Submission: HERE

For subscription options, please visit the website of Springer Nature.

Journal of Planar Chromatography - Modern TLC
Language English
Size A4
Year of
Foundation		 1988
Volumes
per Year		 1
Issues
per Year		 6
Founder Akadémiai Kiadó
Founder's
Address		 H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Publisher Akadémiai Kiadó
Springer Nature Switzerland AG
Publisher's
Address		 H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
CH-6330 Cham, Switzerland Gewerbestrasse 11.
Responsible
Publisher		 Chief Executive Officer, Akadémiai Kiadó
ISSN 0933-4173 (Print)
ISSN 1789-0993 (Online)

Monthly Content Usage

Abstract Views Full Text Views PDF Downloads
Dec 2022 10 0 0
Jan 2023 10 0 0
Feb 2023 1 0 0
Mar 2023 0 0 0
Apr 2023 0 0 0
May 2023 2 0 0
Jun 2023 0 0 0