Journal of Flow Chemistry
Volume/Issue:
Volume 7: Issue 1
The development of high-temperature/high-pressure flow chemistry — A tribute to the pioneering studies of Jürgen O. Metzger
Author:
Bernhard Gutmann University of Graz, Heinrichstrasse 28, A-8010 Graz, Austria
Research Center Pharmaceutical Engineering (RCPE), Inffeldgasse 13, 8010 Graz, Austria

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Pages:
1–3
Online Publication Date:
Mar 2017
Publication Date:
01 Mar 2017
Article Category:
Research Article
DOI:
https://doi.org/10.1556/1846.2016.00038
Restricted access
  • 1. (a)

    Microwave Heating as a Tool for Sustainable Chemistry, Leadbeater, N. E., Ed.; CRC Press: Boca Raton, FL, 2011

  • (b)

    Kappe, C. O.; Stadler, A.; Dallinger, D. Microwaves in Organic and Medicinal Chemistry, 2nd ed.; Wiley-VCH: Weinheim, 2012

  • (c)

    Microwaves in Organic Synthesis, de la Hoz, A.; Loupy, A., Eds.; Wiley-VCH: Weinheim, 2012.

  • 2.

    For a review describing the translation of microwave batch to continuous-flow protocols (“microwave-to-flow paradigm”), see: Glasnov, T. N.; Kappe, C. O. Chem. Eur. J. 2011, 17, 11956–11968.

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  • 3. For reviews on flow chemistry under high-T/p conditions, see: (a)

    Hessel, V.; Kralisch, D.; Krtschil, U. Energy Environ. Sci. 2008, 1, 467–478

  • (b)

    Hessel, V.; Kralisch, D.; Kockmann, N.; Noël, T.; Wang, Q. ChemSusChem 2013, 6, 746–789

  • (c)

    Razzaq, T.; Kappe, C. O. Chem. Asian J. 2010, 5, 1274–1289.

  • 4. For recent general reviews on flow chemistry, see: (a)

    Movsisyan, M.; Delbeke, E. I. P.; Berton, J. K. E. T.; Battilocchio, C.; Ley, S. V.; Stevens, C. V. Chem. Soc. Rev. 2016, 45, 4892–4928

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  • (b)

    Wiles C. ; Watts, P. Green Chem. 2014, 16, 55–62

  • (c)

    Ley, S. V.; Fitzpatrick, D. E.; Ingham R. J.; Myers, R. M. Angew. Chem., Int. Ed. 2015, 54, 3449–3464

  • (d)

    Gutmann, B.; Cantillo, D.; Kappe, C. O. Angew. Chem., Int. Ed. 2015, 54, 6688–6728

  • (e)

    Jensen, K. F.; Reizmana, B. J.; Newman, S. G. Lab Chip 2014, 14, 3206–3212

  • (f)

    Anderson, N. G. Org. Process Res. Dev. 2012, 16, 852–869

  • (g)

    Baxendale, I. R.; Brocken, L.; Mallia, C. J. Green Proc. Synth. 2013, 2, 211–230

  • (h)

    Wiles, C.; Watts, P. Green Chem. 2012, 14, 38–54.

  • 5. (a)

    Hessel, V.; Kralisch D.; Kockmann, N.; Noël, T.; Wang, Q. ChemSusChem 2013, 6, 746–789

  • (b)

    Hessel, V.; Kralisch, D.; Kockmann, N. Novel Process Windows; Wiley-VCH: Weinheim, 2014.

  • 6.

    Hessel, V. Chem. Eng. Technol. 2009, 32, 1655–1681.

  • 7.

    For a recent example where high-T/p conditions were applied for the generation of a pharmaceutical ingredient on a multikilogram scale, see: May, S. A.; Johnson, M. D.; Braden, T. M.; Calvin, J. R.; Haeberle, B. D.; Jines, A. R.; Miller, R. D.; Plocharczyk, E. F.; Rener, G. A.; Richey, R. N.; Schmid, C. R.; Vaid, R. K.; Yu, H. Org. Process Res. Dev. 2012, 16, 982–1002.

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  • 8.

    Köll, P.; Metzger, J. Angew. Chem., Int. Ed. Engl. 1978, 17, 754–755.

  • 9.

    Metzger, J.; Köll, P. Angew. Chem., Int. Ed. Engl. 1979, 18, 70–71.

  • 10.

    Köll, P.; Steinweg, E.; Lackmann, U.; Metzger, J. Tetrahedron Lett. 1979, 3, 223–224.

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    Köll, P.; Steinweg, E.; Meyer, B.; Metzger, J. Liebigs Ann. Chem. 1982, 6, 1039–1051

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    Köll, P.; Steinweg, E.; Meyer, B.; Metzger, J. Liebigs Ann. Chem. 1982, 6, 1063–1067.

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    Metzger, J.; Köll, P. Angew. Chem., Int. Ed. Engl. 1979, 18, 71.

  • 13.

    Metzger, J.; Hartmanns, J.; Köll, P. Tetrahedron Lett. 1981, 22, 1891–1894.

  • 14. (a)

    Metzger, J. Angew. Chem., Int. Ed. Engl. 1983, 22, 889

  • (b)

    Hartmanns, J.; Klenke K.; Metzger, J. O. Chem. Ber. 1986, 119, 488–499

  • (c)

    Metzger, J. O. J. Prakt. Chem. (Leipzig) 1990, 332, 767–781.

  • 15. (a)

    Metzger, J. O.; Klenke, K. Chem. Ber. 1990, 123, 875–879

  • (b)

    Klenke, K.; Metzger, J. O.; Lübben, S. Angew. Chem., Int. Ed. Engl. 1988, 27, 1168–1170.

  • 16.

    Metzger, J. O.; Köll, P. Makromol. Chem. 1983, 184, 63–69.

  • 17. (a)

    Malwitz, D.; Metzger, J. O. Angew. Chem., Int. Ed. Enql. 1986, 25, 762–763

  • (b)

    Malwitz, D.; Metzger, J. O. Chem. Ber. 1986, 119, 3558–3575.

  • 18.

    Fekete, M. ; Glasnov, T. N. In Flow Chemistry. Vol. 1; Darvas, F.; Hessel, V.; Dorman, G. Eds.; De Gruyter: Berlin, 2014; Ch. 4, pp. 95–140.

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Cover Journal of Flow Chemistry
Journal of Flow Chemistry A Journal of the Flow Chemistry Society
Print ISSN:
2062-249X
Online ISSN:
2063-0212

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Journal of Flow Chemistry
Language English
Size A4
Year of
Foundation		 2011
Volumes
per Year		 1
Issues
per Year		 4
Founder Áramlásos Kémiai Tudományos Társaság
Founder's
Address		 H-1031 Budapest, Hungary Záhony utca 7.
Publisher Akadémiai Kiadó
Springer Nature Switzerland AG
Publisher's
Address		 H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
CH-6330 Cham, Switzerland Gewerbestrasse 11
Responsible
Publisher		 Chief Executive Officer, Akadémiai Kiadó
ISSN 2062-249X (Print)
ISSN 2063-0212 (Online)

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