View More View Less
  • 1 Pharmacognosy and Phytochemistry Division, University Department of Pharmaceutical Sciences, Utkal University, Bhubaneswar, 751004, Orissa, India
  • | 2 Department of Chemistry, Lafayette College, Easton, PA, 18042-1782, USA
Full access

Summary

A simple, accurate, and rapid high-performance thin-layer chromatographic (HPTLC) method for quantification of the anticancer marker zerumbone in different parts of Zingiber zerumbet Smith has been established and validated. Chromatography was performed on aluminium foil-backed silica gel 60 F254 HPTLC plates with the binary mobile phase ethyl acetate-hexane 1.5:8.5. Ultraviolet detection was performed densitometrically at the maximum absorbance wavelength, 250 nm. Regression analysis data for the calibration plot showed there was a linear relationship between response and concentration in the range 60–260 ng with a regression coefficient of 0.9997. The limits of detection and quantification were 20 and 60 ng, respectively. The instrumental precision and repeatability of the method were found to be 0.80 and 1.08%, respectively. Recovery ranging from 97.85 to 100.12% indicated the excellent accuracy of the method. The developed HPTLC method was successfully used for analysis of the marker in different parts of Z. zerumbet, and the maximum zerumbone content (1.81%) was found in the rhizome.

  • [1]. The Wealth of India-Raw Materials, Vol. 6, Council of Scientific and Industrial Research, New Delhi, India, 1976, p, 105.

  • [2]. A. Chatterjee S.C. Prakashi 2001 The Treatise of Indian Medicinal Plants, Vol 6 National Institute of Science Communication New Delhi, India 170171.

    • Search Google Scholar
    • Export Citation
  • [3]. S. Dev 2006 Prime Ayurvedic Plant Drugs, Ancient-Modern Concordance Anamaya Publisher New Delhi, India 459462.

  • [4]. H.W.D. Matthes B. Luu G. Ourisson 1980 Phytochemistry 19 2643.

  • [5]. J.R. Dai J.H. Cardellina II J.B. McMahon M.R. Boyd 1997 Nat. Prod. Lett. 10 115.

  • [6]. T. Kitayama K. Yamamoto R. Utsumi M. Takatani R.K. Hill Y. Kawai S. Sawada T. Okamoto 2001 Biosci. Biotechnol. Biochem. 65 2193.

  • [7]. A. Murakami D. Takahashi T. Kinoshita K. Koshimizu H.W. Kim A. Yoshihiro Y. Nakamura S. Jiwajinda J. Terao H. Ohigashi 2002 Carcinogenesis 23 795.

    • Search Google Scholar
    • Export Citation
  • [8]. S.M. Nhareet M.H. Nur Shukriyah 2003 Indian J. Pharmacol. 35 181.

  • [9]. T. Masuda A. Jitoe S. Kato N. Nakatani 1991 Phytochemistry 30 2391.

  • [10]. D.S. Jang A.R. Han G. Park G.J. Jhon E.K. Seo 2004 Arch. Pharm. Res. 27 386.

  • [11]. S.Y. Chung D.S. Jang A.R. Han J.O. Jang Y. Kwon E.K. Seo H.J. Lee 2007 Phytother. Res. 21 565.

  • [12]. C. Kirana G.H. McIntosh I.R. Record G.P. Jones 2003 Nutr. Cancer 45 218.

  • [13]. Y. Takada A. Murakami B.B. Aggarwal 2005 Oncogene 24 6957.

  • [14]. G.C. Huang T.Y. Chien L.G. Chen C.C. Wang 2005 Planta Med. 71 219.

  • [15]. C. Charegaonkar 2001 Pulse 7 13.

  • [16]. P.D. Sethi 1996 HPTLC Quantitative Analysis of Pharmaceutical Formulations CBS Publishers and Distributors New Delhi, India 162.

  • [17]. S. Dev 1960 Tetrahedron 8 171.

  • [18]. A. Murakami M. Takahashi S. Jiwajinda K. Koshimizu H. Ohigashi 1999 Biosci. Biotechnol. Biochem. 63 1811.

  • [19]. T.Y. Chien L.G. Chen C.J. Lee F.Y. Lee C.C. Wang 2008 Food Chem. 110 584.

  • [20]. K.K. Rout S. Pradhan S.K. Mishra 2008 J. AOAC Int. 91 1149.

  • [21]. K.K. Rout S. Parida S.K. Mishra 2008 J. AOAC Int. 91 1162.

The author instruction is available in PDF.
Please, download the file from HERE.
 
The Open Access statement together with the description of the Copyright and License Policy are available in PDF.
Please, download the file from HERE.
 

 

Senior editors

Editor(s)-in-Chief: Kowalska, Teresa

Editor(s)-in-Chief: Sajewicz, Mieczyslaw

Editors(s) Danica Agbaba (University of Belgrade, Belgrade, Serbia);
Ivana Stanimirova-Daszykowska (University of Silesia, Katowice, Poland),
Monika Waksmundzka-Hajnos (Medical University of Lublin, Lublin, Poland)

Editorial Board

R. Bhushan (The Indian Institute of Technology, Roorkee, India)
J. Bojarski (Jagiellonian University, Kraków, Poland)
B. Chankvetadze (State University of Tbilisi, Tbilisi, Georgia)
M. Daszykowski (University of Silesia, Katowice, Poland)
T.H. Dzido (Medical University of Lublin, Lublin, Poland)
A. Felinger (University of Pécs, Pécs, Hungary)
K. Glowniak (Medical University of Lublin, Lublin, Poland)
B. Glód (Siedlce University of Natural Sciences and Humanities, Siedlce, Poland)
K. Kaczmarski (Rzeszow University of Technology, Rzeszów, Poland)
H. Kalász (Semmelweis University, Budapest, Hungary)
I. Klebovich (Semmelweis University, Budapest, Hungary)
A. Koch (Private Pharmacy, Hamburg, Germany)
Ł. Komsta (Medical University of Lublin, Lublin, Poland)
P. Kus (Univerity of Silesia, Katowice, Poland)
D. Mangelings (Free University of Brussels, Brussels, Belgium)
E. Mincsovics (Corvinus University of Budapest, Budapest, Hungary)
G. Morlock (Giessen University, Giessen, Germany)
J. Sherma (Lafayette College, Easton, PA, USA)
R. Skibiński (Medical University of Lublin, Lublin, Poland)
B. Spangenberg (Offenburg University of Applied Sciences, Germany)
T. Tuzimski (Medical University of Lublin, Lublin, Poland)
Y. Vander Heyden (Free University of Brussels, Brussels, Belgium)
A. Voelkel (Poznań University of Technology, Poznań, Poland)
B. Walczak (University of Silesia, Katowice, Poland)
W. Wasiak (Adam Mickiewicz University, Poznań, Poland)

KOWALSKA, TERESA
E-mail: kowalska@us.edu.pl

SAJEWICZ, MIECZYSLAW
E-mail:msajewic@us.edu.pl

Indexing and Abstracting Services:

  • Science Citation Index
  • Sci Search
  • Research Alert
  • Chemistry Citation Index and Current Content/Physical
  • Chemical and Earth Sciences
  • SCOPUS
  • GoogleScholar
  • Index Copernicus
  • CABI
2020
 
Total Cites
650
WoS
Journal
Impact Factor
1,639
Rank by
Chemistry, Analytical 71/83 (Q4)
Impact Factor
 
Impact Factor
1,412
without
Journal Self Cites
5 Year
1,301
Impact Factor
Journal
0,34
Citation Indicator
 
Rank by Journal
Chemistry, Analytical 75/93 (Q4)
Citation Indicator
 
Citable
45
Items
Total
43
Articles
Total
2
Reviews
Scimago
28
H-index
Scimago
0,316
Journal Rank
Scimago
Chemistry (miscellaneous) Q3
Quartile Score
 
Scopus
393/181=2,2
Scite Score
 
Scopus
General Chemistry 215/398 (Q3)
Scite Score Rank
 
Scopus
0,560
SNIP
 
Days from
58
sumbission
 
to acceptance
 
Days from
68
acceptance
 
to publication
 
Acceptance
51%
Rate

2019  
Total Cites
WoS
495
Impact Factor 1,418
Impact Factor
without
Journal Self Cites
1,374
5 Year
Impact Factor
0,936
Immediacy
Index
0,460
Citable
Items
50
Total
Articles
50
Total
Reviews
0
Cited
Half-Life
6,2
Citing
Half-Life
8,3
Eigenfactor
Score
0,00048
Article Influence
Score
0,164
% Articles
in
Citable Items
100,00
Normalized
Eigenfactor
0,05895
Average
IF
Percentile
20,349
Scimago
H-index
26
Scimago
Journal Rank
0,255
Scopus
Scite Score
226/167=1,4
Scopus
Scite Score Rank
Chemistry (miscellaneous) 240/398 (Q3)
Scopus
SNIP
0,494
Acceptance
Rate
41%

 

Acta Chromatographica
Publication Model Online only
Gold Open Access
Submission Fee none
Article Processing Charge 400 EUR/article
Regional discounts on country of the funding agency World Bank Lower-middle-income economies: 50%
World Bank Low-income economies: 100%
Further Discounts Editorial Board / Advisory Board members: 50%
Corresponding authors, affiliated to an EISZ member institution subscribing to the journal package of Akadémiai Kiadó: 100%
Subscription Information Gold Open Access
Purchase per Title  

Acta Chromatographica
Language English
Size A4
Year of
Foundation
1992
Publication
Programme
2021 Volume 33
Volumes
per Year
1
Issues
per Year
4
Founder Institute of Chemistry, University of Silesia
Founder's
Address
PL-40-007 Katowice, Poland, Bankowa 12
Publisher Akadémiai Kiadó
Publisher's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Responsible
Publisher
Chief Executive Officer, Akadémiai Kiadó
ISSN 2083-5736 (Online)

Monthly Content Usage

Abstract Views Full Text Views PDF Downloads
May 2021 5 0 0
Jun 2021 8 0 0
Jul 2021 8 2 5
Aug 2021 0 3 1
Sep 2021 0 3 2
Oct 2021 0 3 3
Nov 2021 0 0 0